Sökning: id:"swepub:oai:lup.lub.lu.se:9303396b-ea1b-4e32-9470-542c00ccfcd5" >
The Wisdom in Teeth...
The Wisdom in Teeth : Neuronal Differentiation of Dental Pulp Cells
-
- Sramkó, Bendegúz (författare)
- Semmelweis University
-
- Földes, Anna (författare)
- Semmelweis University
-
- Kádár, Kristóf (författare)
- Semmelweis University
-
visa fler...
-
- Varga, Gábor (författare)
- Semmelweis University
-
- Zsembery, Ákos (författare)
- Semmelweis University
-
- Pircs, Karolina (författare)
- Lund University,Lunds universitet,Molekylär neurogenetik,Forskargrupper vid Lunds universitet,LU profilområde: Proaktivt åldrande,Lunds universitets profilområden,Molecular Neurogenetics,Lund University Research Groups,LU Profile Area: Proactive Ageing,Lund University Profile areas,Semmelweis University
-
visa färre...
-
(creator_code:org_t)
- Mary Ann Liebert Inc, 2023
- 2023
- Engelska 13 s.
-
Ingår i: Cellular Reprogramming. - : Mary Ann Liebert Inc. - 2152-4971 .- 2152-4998. ; 25:1, s. 32-44
- Relaterad länk:
-
http://dx.doi.org/10... (free)
-
visa fler...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Mesenchymal stem/stromal cells (MSCs) are found in almost all postnatal organs. Under appropriate environmental cues, multipotency enables MSCs to serve as progenitors for several lineage-specific, differentiated cell types. In vitro expansion and differentiation of MSCs give the opportunity to obtain hardly available somatic cells, such as neurons. The neurogenic potential of MSCs makes them a promising, autologous source to restore damaged tissue and as such, they have received much attention in the field of regenerative medicine. Several stem cell pool candidates have been studied thus far, but only a few of them showed neurogenic differentiation potential. Due to their embryonic ontology, stem cells residing in the stroma of the dental pulp chamber are an exciting source for in vitro neural cell differentiation. In this study, we review the key properties of dental pulp stem cells (DPSCs), with a particular focus on their neurogenic potential. Moreover, we summarize the various presently available methods used for neural differentiation of human DPSCs also emphasizing the difficulties in reproducibly high production of such cells. We postulate that because DPSCs are stem cells with very close ontology to neurogenic lineages, they may serve as excellent targets for neuronal differentiation in vitro and even for direct reprogramming.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
Nyckelord
- dental pulp stem cells
- mesenchymal stem cells
- neural crest
- neural differentiation
- reprogramming
Publikations- och innehållstyp
- for (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas