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Prevalence of and r...
Prevalence of and risk factors for chronic kidney disease of unknown aetiology in India : Secondary data analysis of three population-based cross-sectional studies
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- O'Callaghan-Gordo, Cristina (författare)
- London School of Hygiene and Tropical Medicine,CIBER Epidemiology and Public Health (CIBERESP),Pompeu Fabra University,Centre for Research in Environmental Epidemiology
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- Shivashankar, Roopa (författare)
- Public Health Foundation of India,Centre for Chronic Disease Control, India
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- Anand, Shuchi (författare)
- Stanford University
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- Ghosh, Shreeparna (författare)
- Public Health Foundation of India
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- Glaser, Jason (författare)
- La Isla Network,London School of Hygiene and Tropical Medicine
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- Gupta, Ruby (författare)
- Public Health Foundation of India
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- Jakobsson, Kristina (författare)
- Gothenburg University,Göteborgs universitet,University of Gothenburg,Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för arbets-och miljömedicin,Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine
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- Kondal, Dimple (författare)
- Centre for Chronic Disease Control, India,Public Health Foundation of India
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- Krishnan, Anand (författare)
- All India Institute of Medical Sciences
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- Mohan, Sailesh (författare)
- Public Health Foundation of India
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- Mohan, Viswanathan (författare)
- Madras Diabetes Research Foundation
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- Nitsch, Dorothea (författare)
- London School of Hygiene and Tropical Medicine
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- Praveen, P. A. (författare)
- All India Institute of Medical Sciences,Centre for Chronic Disease Control, India
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- Tandon, Nikhil (författare)
- All India Institute of Medical Sciences
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- Narayan, K. M.Venkat (författare)
- Emory University
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- Pearce, Neil (författare)
- London School of Hygiene and Tropical Medicine
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- Caplin, Ben (författare)
- University College London
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- Prabhakaran, Dorairaj (författare)
- Public Health Foundation of India,Centre for Chronic Disease Control, India
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(creator_code:org_t)
- 2019-03-07
- 2019
- Engelska.
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Ingår i: BMJ Open. - : BMJ. - 2044-6055. ; 9:3
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http://dx.doi.org/10... (free)
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https://bmjopen.bmj....
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Objectives To assess whether chronic kidney disease of unknown aetiology (CKDu) is present in India and to identify risk factors for it using population-based data and standardised methods. Design Secondary data analysis of three population-based cross-sectional studies conducted between 2010 and 2014. Setting Urban and rural areas of Northern India (states of Delhi and Haryana) and Southern India (states of Tamil Nadu and Andhra Pradesh). Participants 12 500 individuals without diabetes, hypertension or heavy proteinuria. Outcome measures Mean estimated glomerular filtration rate (eGFR) and prevalence of eGFR below 60 mL/min per 1.73 m 2 (eGFR <60) in individuals without diabetes, hypertension or heavy proteinuria (proxy definition of CKDu). Results The mean eGFR was 105.0±17.8 mL/min per 1.73 m 2. The prevalence of eGFR <60 was 1.6% (95% CI=1.4 to 1.7), but this figure varied markedly between areas, being highest in rural areas of Southern Indian (4.8% (3.8 to 5.8)). In Northern India, older age was the only risk factor associated with lower mean eGFR and eGFR <60 (regression coefficient (95% CI)=a '0.94 (0.97 to 0.91); OR (95% CI)=1.10 (1.08 to 1.11)). In Southern India, risk factors for lower mean eGFR and eGFR <60, respectively, were residence in a rural area (a '7.78 (-8.69 to -6.86); 4.95 (2.61 to 9.39)), older age (a '0.90 (-0.93 to -0.86); 1.06 (1.04 to 1.08)) and less education (a '0.94 (-1.32 to -0.56); 0.67 (0.50 to 0.90) for each 5 years at school). Conclusions CKDu is present in India and is not confined to Central America and Sri Lanka. Identified risk factors are consistent with risk factors previously reported for CKDu in Central America and Sri Lanka.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- chronic renal failure
- epidemiology
- nephrology
- public health
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O'Callaghan-Gord ...
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Shivashankar, Ro ...
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Anand, Shuchi
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Ghosh, Shreeparn ...
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Glaser, Jason
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Gupta, Ruby
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Jakobsson, Krist ...
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Kondal, Dimple
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Krishnan, Anand
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Mohan, Sailesh
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Mohan, Viswanath ...
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Nitsch, Dorothea
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Praveen, P. A.
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Tandon, Nikhil
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Narayan, K. M.Ve ...
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Pearce, Neil
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Caplin, Ben
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Prabhakaran, Dor ...
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