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Patch testing with ...
Patch testing with methyldibromo glutaronitrile, a multicentre study within the EECDRG
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- Gruvberger, Birgitta (författare)
- Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine
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Andersen, KE (författare)
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Brandao, FM (författare)
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Bruynzeel, DP (författare)
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- Bruze, Magnus (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups
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Frosch, PJ (författare)
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Goossens, A (författare)
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Lahti, A (författare)
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- Lindberg, M (författare)
- Karolinska Institutet
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Menne, T (författare)
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Orton, D (författare)
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Seidenari, S (författare)
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(creator_code:org_t)
- Wiley, 2005
- 2005
- Engelska.
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 52:1, s. 14-18
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Contact allergy to and allergic contact dermatitis from methyldibromo glutaronitrile (MDBGN) have frequently been reported. As there has been no agreement on which MDBGN test preparation to use, a study was initiated to help determine the optimal patch test preparation for MDBGN. 2661 consecutively patch tested patients at 11 test clinics representing 9 European countries participated. Petrolatum preparations with MDBGN at 1.0%, 0.5%, 0.3% and 0.1% were inserted in the standard series. Contact allergy rates were noted in the range 4.4-1.1% following decreasing test concentrations. Reactions not fulfilling all criteria to be classified as allergic reactions could represent either weak allergic or irritant reactions, and such reactions were noted in the range 8.2-0.5% with decreasing concentrations. A significant number of these reactions represented weak allergic reactions, as allergic reactions were obtained to higher patch test concentrations in the same individual. Morphologically irritant reactions were noted only for the highest test concentrations. In summary, the contact allergy rates and frequencies of doubtful and irritant reactions vary with the patch test concentration. The final decision on patch test concentration for MDBGN should not only rely on these factors but also include information on patch test concentrations required to diagnose individual cases with allergic contact dermatitis from MDBGN as well as results of repeated open application tests.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Nyckelord
- Tektamer 38
- preservative
- methyldibromo glutaronitrile
- Euxyl K400
- series
- European standard test
- contact allergy
- CAS 35691-65-7
- dermatitis
- allergic contact
- 4-dicyanobutane
- 2-dibromo-2
- 1
- adverse reactions
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Gruvberger, Birg ...
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Andersen, KE
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Brandao, FM
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Bruynzeel, DP
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Bruze, Magnus
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Frosch, PJ
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visa fler...
-
Goossens, A
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Lahti, A
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Lindberg, M
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Menne, T
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Orton, D
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Seidenari, S
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Dermatologi och ...
- Artiklar i publikationen
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Contact Dermatit ...
- Av lärosätet
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Lunds universitet
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Karolinska Institutet