Sökning: id:"swepub:oai:lup.lub.lu.se:de009b8c-ab2d-4114-bd1b-eef9cfb77651" >
ESO Guideline on co...
ESO Guideline on covert cerebral small vessel disease
-
- Wardlaw, Joanna M. (författare)
- University of Edinburgh
-
- Debette, Stephanie (författare)
- University of Bordeaux,Centre Hospitalier Universitaire de Bordeaux
-
- Jokinen, Hanna (författare)
- Helsinki University Central Hospital
-
visa fler...
-
- De Leeuw, Frank Erik (författare)
- Radboud University Medical Center
-
- Pantoni, Leonardo (författare)
- Luigi Sacco University Hospital
-
- Chabriat, Hugues (författare)
- Paris Diderot University
-
- Staals, Julie (författare)
- Maastricht University Medical Centre
-
- Doubal, Fergus (författare)
- University of Edinburgh
-
- Rudilosso, Salvatore (författare)
- Hospital Clínic of Barcelona
-
- Eppinger, Sebastian (författare)
- Medical University of Graz
-
- Schilling, Sabrina (författare)
- University of Bordeaux
-
- Ornello, Raffaele (författare)
- University of L'Aquila
-
- Enzinger, Christian (författare)
- Medical University of Graz
-
- Cordonnier, Charlotte (författare)
- University of Lille
-
- Taylor-Rowan, Martin (författare)
- Glasgow Royal Infirmary
-
- Lindgren, Arne G. (författare)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Klinisk strokeforskning,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Stroke Research Group,Lund University Research Groups
-
visa färre...
-
(creator_code:org_t)
- 2021-05-11
- 2021
- Engelska.
-
Ingår i: European Stroke Journal. - : SAGE Publications. - 2396-9873 .- 2396-9881. ; 6:2
- Relaterad länk:
-
http://dx.doi.org/10... (free)
-
visa fler...
-
https://journals.sag...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- ‘Covert’ cerebral small vessel disease (ccSVD) is common on neuroimaging in persons without overt neurological manifestations, and increases the risk of future stroke, cognitive impairment, dependency, and death. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist with clinical decisions about management of ccSVD, specifically white matter hyperintensities and lacunes, to prevent adverse clinical outcomes. The guidelines were developed according to ESO standard operating procedures and Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology. We prioritised the clinical outcomes of stroke, cognitive decline or dementia, dependency, death, mobility and mood disorders, and interventions of blood pressure lowering, antiplatelet drugs, lipid lowering, lifestyle modifications, glucose lowering and conventional treatments for dementia. We systematically reviewed the literature, assessed the evidence, formulated evidence-based recommendations where feasible, and expert consensus statements. We found little direct evidence, mostly of low quality. We recommend patients with ccSVD and hypertension to have their blood pressure well controlled; lower blood pressure targets may reduce ccSVD progression. We do not recommend antiplatelet drugs such as aspirin in ccSVD. We found little evidence on lipid lowering in ccSVD. Smoking cessation is a health priority. We recommend regular exercise which may benefit cognition, and a healthy diet, good sleep habits, avoiding obesity and stress for general health reasons. In ccSVD, we found no evidence for glucose control in the absence of diabetes or for conventional Alzheimer dementia treatments. Randomised controlled trials with clinical endpoints are a priority for ccSVD.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- cerebral small vessel disease
- covert
- dementia
- lacunes
- leukoaraiosis
- outcome
- prevention
- recommendations
- silent brain infarcts
- stroke
- White matter hyperintensities
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Wardlaw, Joanna ...
-
Debette, Stephan ...
-
Jokinen, Hanna
-
De Leeuw, Frank ...
-
Pantoni, Leonard ...
-
Chabriat, Hugues
-
visa fler...
-
Staals, Julie
-
Doubal, Fergus
-
Rudilosso, Salva ...
-
Eppinger, Sebast ...
-
Schilling, Sabri ...
-
Ornello, Raffael ...
-
Enzinger, Christ ...
-
Cordonnier, Char ...
-
Taylor-Rowan, Ma ...
-
Lindgren, Arne G ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Neurologi
- Artiklar i publikationen
-
European Stroke ...
- Av lärosätet
-
Lunds universitet