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Changes in cortical...
Changes in cortical dopamine D1 receptor binding associated with cognitive training
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- McNab, F (författare)
- Karolinska Institutet
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- Varrone, A (författare)
- Karolinska Institutet
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- Farde, L (författare)
- Karolinska Institutet
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- Jucaite, A (författare)
- Karolinska Institutet
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Bystritsky, P (författare)
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- Forssberg, H (författare)
- Karolinska Institutet
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- Klingberg, T (författare)
- Karolinska Institutet
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(creator_code:org_t)
- American Association for the Advancement of Science (AAAS), 2009
- 2009
- Engelska.
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Ingår i: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 323:5915, s. 800-802
- Relaterad länk:
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http://kipublication...
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https://doi.org/10.1...
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Abstract
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- Working memory is a key function for human cognition, dependent on adequate dopamine neurotransmission. Here we show that the training of working memory, which improves working memory capacity, is associated with changes in the density of cortical dopamine D1 receptors. Fourteen hours of training over 5 weeks was associated with changes in both prefrontal and parietal D1 binding potential. This plasticity of the dopamine D1 receptor system demonstrates a reciprocal interplay between mental activity and brain biochemistry in vivo.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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