Specific dsDNA recognition by a mimic of the DNA binding domain of the c-Myc/Max transcription factor

• We here report on the synthesis of the first mimic of the DNA binding domain of the c-Myc/Max-bHLH-ZIP transcription factor able to selectively recognize its cognate E-box sequence 5′-CACGTG-3′ through the major groove of the double-stranded DNA.

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