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Stroke in the Middl...
Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region-Results from the Safe Implementation of Treatments in Stroke (SITS)-Middle-East and North African (MENA)
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Al Rukn, S (author)
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- Mazya, MV (author)
- Karolinska Institutet
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Hentati, F (author)
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Ben Sassi, S (author)
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Nabli, F (author)
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Said, Z (author)
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Faouzi, B (author)
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Hashim, H (author)
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Abd-Allah, F (author)
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Mansouri, B (author)
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Kesraoui, S (author)
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Gebeily, S (author)
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Abdulrahman, H (author)
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Akhtar, N (author)
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- Ahmed, N (author)
- Karolinska Institutet
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- Wahlgren, N (author)
- Karolinska Institutet
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Aref, H (author)
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Almekhlafi, M (author)
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- Moreira, T (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2019-03-12
- 2019
- English.
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In: International journal of stroke : official journal of the International Stroke Society. - : SAGE Publications. - 1747-4949. ; 14:7, s. 715-722
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https://doi.org/10.1...
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Abstract
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- Stroke incidence and mortality are reported to have increased in the Middle-East and North African (MENA) countries during the last decade. This was a prospective observational study to examine the baseline characteristics of stroke patients in the MENA region and to compare the MENA vs. the non-MENA stroke cohort in the Safe Implementation of Treatments in Stroke (SITS) International Registry. Results Of the 13,822 patients with ischemic and hemorrhagic stroke enrolled in the SITS-All Patients Protocol between June 2014 and May 2016, 5897 patients (43%) were recruited in MENA. The median onset-to-door time was 5 h (IQR: 2:20–13:00), National Institutes of Health Stroke Scale (NIHSS) score was 8 (4–13) and age was 65 years (56–76). Hypertension (66%) and diabetes (38%) were the prevailing risk factors; large artery stenosis > 50% (25.3%) and lacunar strokes (24.1%) were the most common ischemic stroke etiologies. In comparison, non-MENA countries displayed an onset-to-door time of 5:50 h (2:00–18:45), a median of NIHSS 6 (3–14), and a median age of 66 (56–76), with other large vessel disease and cardiac embolism as the main ischemic stroke etiologies. Hemorrhagic strokes (10%) were less common compared to non-MENA countries (13.9%). In MENA, only a low proportion of patients (21%) was admitted to stroke units. Conclusions MENA patients are slightly younger, have a higher prevalence of diabetes and slightly more severe ischemic strokes, commonly of atherosclerotic or microvascular etiology. Admission into stroke units and long-term follow-up need to be improved. It is suspected that cardiac embolism and atrial fibrillation are currently underdiagnosed in MENA countries.
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- By the author/editor
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Al Rukn, S
-
Mazya, MV
-
Hentati, F
-
Ben Sassi, S
-
Nabli, F
-
Said, Z
-
show more...
-
Faouzi, B
-
Hashim, H
-
Abd-Allah, F
-
Mansouri, B
-
Kesraoui, S
-
Gebeily, S
-
Abdulrahman, H
-
Akhtar, N
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Ahmed, N
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Wahlgren, N
-
Aref, H
-
Almekhlafi, M
-
Moreira, T
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show less...
- Articles in the publication
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International jo ...
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International Jo ...
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Karolinska Institutet