Sökning: id:"swepub:oai:prod.swepub.kib.ki.se:145567043" >
Exposure to Medical...
Exposure to Medical Radiation during Fetal Life, Childhood and Adolescence and Risk of Brain Tumor in Young Age: Results from The MOBI-Kids Case-Control Study
-
Pasqual, E (författare)
-
Castano-Vinyals, G (författare)
-
Thierry-Chef, I (författare)
-
visa fler...
-
Kojimahara, N (författare)
-
Sim, MR (författare)
-
Kundi, M (författare)
-
Krewski, D (författare)
-
Momoli, F (författare)
-
Lacour, B (författare)
-
Remen, T (författare)
-
Radon, K (författare)
-
Weinmann, T (författare)
-
Petridou, E (författare)
-
Moschovi, M (författare)
-
Dikshit, R (författare)
-
Sadetski, S (författare)
-
Maule, M (författare)
-
Farinotti, M (författare)
-
Ha, M (författare)
-
Mannetje, A (författare)
-
Alguacil, J (författare)
-
Aragones, N (författare)
-
Vermeulen, R (författare)
-
Kromhout, H (författare)
-
Cardis, E (författare)
-
visa färre...
- 2020-03-20
- 2020
- Engelska.
-
Ingår i: Neuroepidemiology. - : S. Karger AG. - 1423-0208 .- 0251-5350. ; 54:4, s. 343-355
- Relaterad länk:
-
http://repositori.up...
-
visa fler...
-
http://kipublication...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- <b><i>Background:</i></b> We explored the association between ionizing radiation (IR) from pre-natal and post-natal radio-diagnostic procedures and brain cancer risk within the MOBI-kids study. <b><i>Methods:</i></b> MOBI-kids is an international (Australia, Austria, Canada, France, Germany, Greece, India, Israel, Italy, Japan, Korea, New Zealand, Spain, The Netherlands) case-control study including 899 brain tumor (645 neuroepithelial) cases aged 10–24 years and 1,910 sex-, age-, country-matched controls. Medical radiological history was collected through personal interview. We estimated brain IR dose for each procedure, building a look-up table by age and time period. Lifetime cumulative doses were calculated using 2 and 5 years lags from the diagnostic date. Risk was estimated using conditional logistic regression. Neurological, psychological and genetic conditions were evaluated as potential confounders. The main analyses focused on neuroepithelial tumors. <b><i>Results:</i></b> Overall, doses were very low, with a skewed distribution (median 0.02 mGy, maximum 217 mGy). ORs for post-natal exposure were generally below 1. ORs were increased in the highest dose categories both for post and pre-natal exposures: 1.63 (95% CI 0.44–6.00) and 1.55 (0.57–4.23), respectively, based on very small numbers of cases. The change in risk estimates after adjustment for medical conditions was modest. <b><i>Conclusions:</i></b> There was little evidence for an association between IR from radio-diagnostic procedures and brain tumor risk in children and adolescents. Though doses were very low, our results suggest a higher risk for pre-natal and early life exposure, in line with current evidence.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Pasqual, E
-
Castano-Vinyals, ...
-
Thierry-Chef, I
-
Kojimahara, N
-
Sim, MR
-
Kundi, M
-
visa fler...
-
Krewski, D
-
Momoli, F
-
Lacour, B
-
Remen, T
-
Radon, K
-
Weinmann, T
-
Petridou, E
-
Moschovi, M
-
Dikshit, R
-
Sadetski, S
-
Maule, M
-
Farinotti, M
-
Ha, M
-
Mannetje, A
-
Alguacil, J
-
Aragones, N
-
Vermeulen, R
-
Kromhout, H
-
Cardis, E
-
visa färre...
- Artiklar i publikationen
-
Neuroepidemiolog ...
- Av lärosätet
-
Karolinska Institutet