Sökning: id:"swepub:oai:prod.swepub.kib.ki.se:152198545" >
Postnatal growth re...
Postnatal growth restriction and neurodevelopment at 5 years of age: a European extremely preterm birth cohort study
-
El Rafei, R (författare)
-
Maier, RF (författare)
-
Jarreau, PH (författare)
-
visa fler...
-
- Norman, M (författare)
- Karolinska Institutet
-
Barros, H (författare)
-
Van Reempts, P (författare)
-
Van Heijst, A (författare)
-
Pedersen, P (författare)
-
Cuttini, M (författare)
-
Johnson, S (författare)
-
Costa, R (författare)
-
Zemlin, M (författare)
-
Draper, ES (författare)
-
Zeitlin, J (författare)
-
visa färre...
-
(creator_code:org_t)
- 2023-03-03
- 2023
- Engelska.
-
Ingår i: Archives of disease in childhood. Fetal and neonatal edition. - : BMJ. - 1468-2052 .- 1359-2998. ; 108:5, s. F492-F498
- Relaterad länk:
-
http://kipublication...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- To investigate whether extrauterine growth restriction (EUGR) during the neonatal hospitalisation by sex among extremely preterm (EPT) infants is associated with cerebral palsy (CP) and cognitive and motor abilities at 5 years of age.Study designPopulation-based cohort of births <28 weeks of gestation with data from obstetric and neonatal records and parental questionnaires and clinical assessments at 5 years of age.Setting11 European countries.Patients957 EPT infants born in 2011–2012.Main outcomesEUGR at discharge from the neonatal unit was defined as (1) the difference between Z-scores at birth and discharge with <−2 SD as severe, −2 to −1 SD as moderate using Fenton’s growth charts (Fenton) and (2) average weight-gain velocity using Patel’s formula in grams (g) per kilogram per day (Patel) with <11.2 g (first quartile) as severe, 11.2–12.5 g (median) as moderate. Five-year outcomes were: a CP diagnosis, intelligence quotient (IQ) using the Wechsler Preschool and Primary Scales of Intelligence tests and motor function using the Movement Assessment Battery for Children, second edition.Results40.1% and 33.9% children were classified as having moderate and severe EUGR, respectively, by Fenton and 23.8% and 26.3% by Patel. Among children without CP, those with severe EUGR had lower IQ than children without EUGR (−3.9 points, 95% Confidence Interval (CI)=−7.2 to −0.6 for Fenton and −5.0 points, 95% CI=−8.2 to −1.8 for Patel), with no interaction by sex. No significant associations were observed between motor function and CP.ConclusionsSevere EUGR among EPT infants was associated with decreased IQ at 5 years of age.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
El Rafei, R
-
Maier, RF
-
Jarreau, PH
-
Norman, M
-
Barros, H
-
Van Reempts, P
-
visa fler...
-
Van Heijst, A
-
Pedersen, P
-
Cuttini, M
-
Johnson, S
-
Costa, R
-
Zemlin, M
-
Draper, ES
-
Zeitlin, J
-
visa färre...
- Artiklar i publikationen
-
Archives of dise ...
- Av lärosätet
-
Karolinska Institutet