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Terahertz radar observes powder dynamics for pharmaceutical manufacturing

Bonmann, Marlene, 1988 (author)
Chalmers tekniska högskola,Chalmers University of Technology
Moradikouchi, Anis, 1990 (author)
Chalmers tekniska högskola,Chalmers University of Technology
Bryllert, Tomas, 1974 (author)
Chalmers tekniska högskola,Chalmers University of Technology
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Sparén, Anders (author)
AstraZeneca R&D Mölndal
Folestad, Staffan, 1954 (author)
Chalmers tekniska högskola,Chalmers University of Technology
Johansson, Jonas (author)
AstraZeneca R&D Mölndal
Stake, Jan, 1971 (author)
Chalmers tekniska högskola,Chalmers University of Technology
Rodilla, Helena, 1982 (author)
Chalmers tekniska högskola,Chalmers University of Technology
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 (creator_code:org_t)
2024
2024
English.
In: IEEE Sensors Journal. - 1558-1748 .- 1530-437X. ; 24:13, s. 20512-20522
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The optical opaqueness of powders has precluded the observation of powder flow dynamics in processing tubes, with important implications, for example, in the pharmaceutical industry, where non-destructive monitoring during the manufacturing process is essential to ensure the quality of the final product and the effectiveness of the process. Taking advantage of the high penetration of terahertz electromagnetic waves in powders and its wavelength-to-particle size ratio, we demonstrate that a submillimeter-wave pulse-Doppler radar can overcome the present challenges and characterize powder flow dynamics in pharmaceutical manufacturing processes. Mimicking typical vessel shapes in pharmaceutical operations, we were able to characterize falling powder streams in a tube with a sample volume resolution of a few cubic centimeters and a range resolution of about 5 mm. We successfully monitored particle velocity, particle distribution within the tube, and mass flow rate in real-time. This remote sensing method, based on advanced terahertz electronics, opens up the possibility to study and monitor powder dynamics in a wide range of applications.

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Elektroteknik och elektronik -- Annan elektroteknik och elektronik (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Electrical Engineering, Electronic Engineering, Information Engineering -- Other Electrical Engineering, Electronic Engineering, Information Engineering (hsv//eng)

Keyword

Pharmaceuticals
Sensors
Radar
Remote sensing
Radars
Doppler radar
Frequency-modulated continuous-wave (FMCW)
Radar cross-sections
Doppler radar
Streams
Powders
THz sensors
Terahertz systems
Electron tubes
Submillimeter waves

Publication and Content Type

art (subject category)
ref (subject category)

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