Non-invasive EEG source localization using particle swarm optimization: A clinical experiment

• One of the most important steps of pre-surgical diagnosis in patients with medically intractable epilepsy is to find the precise location of the epileptogenic foci. An Electroencephalography (EEG) is a non-invasive standard tool used at epilepsy surgery center for pre-surgical diagnosis. In this paper a modified particle swarm optimization (MPSO) method is applied to a real EEG data, i.e., a somatosensory evoked potentials (SEPs) measured from a healthy subject, to solve the EEG source localization problem. A high resolution 1 mm hexahedra finite element volume conductor model of the subject's head was generated using T1-weighted magnetic resonance imaging data. An exhaustive search pattern and the MPSO method were then applied to the peak of the averaged SEPs data. The non-invasive EEG source analysis methods localized the somatosensory cortex area where our clinical expert expected the received SEPs. The proposed inverse problem solver found the global minima with acceptable accuracy and reasonable number of iterations.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Medicinteknik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Medical Engineering (hsv//eng)

Nyckelord

High resolution

Global minima

Epileptogenic foci

Somatosensory cortex

Modified particle swarm optimization

EEG source localization

Somatosensory evoked potentials

Epilepsy surgery

Finite Element

Source analysis method

Number of iterations

T1-weighted magnetic resonance imaging

Exhaustive search

Healthy subjects

Standard tools

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