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Targeting the deliv...
Targeting the delivery of dietary plant bioactives to those who would benefit most: from science to practical applications
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- de Roos, Baukje (författare)
- University of Aberdeen
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- Aura, Anna-Marja (författare)
- Teknologian Tutkimuskeskus (VTT),Technical Research Centre of Finland (VTT)
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- Bronze, Maria (författare)
- Instituto de Biologia Experimental e Tecnologica
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- Cassidy, Aedin (författare)
- University of East Anglia
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Garcia Conesa, Maria-Teresa (författare)
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- Gibney, Eileen R. (författare)
- University College Dublin, National University Of Ireland
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- Greyling, Arno (författare)
- Unilever
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Kaput, Jim (författare)
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- Kerem, Zohar (författare)
- The Hebrew University Of Jerusalem
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Knezevic, Nada (författare)
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- Kroon, Paul (författare)
- Quadram Institute
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- Landberg, Rikard, 1981 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Manach, Claudine (författare)
- Université Clermont Auvergne,Clermont Auvergne University
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- Milenkovic, Dragan (författare)
- Université Clermont Auvergne,Clermont Auvergne University
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- Rodriguez-Mateos, Ana (författare)
- King's College London
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Tomas-Barberan, Francisco A. (författare)
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- van de Wiele, Tom (författare)
- Universiteit Gent,Ghent university
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- Morand, Christine (författare)
- Université Clermont Auvergne,Clermont Auvergne University
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(creator_code:org_t)
- 2019-10-22
- 2019
- Engelska.
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Ingår i: European Journal of Nutrition. - : Springer Science and Business Media LLC. - 1436-6207 .- 1436-6215. ; 58:53 (suppl. 2), s. 65-73
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Abstract
Ämnesord
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- Background A healthy diet and optimal lifestyle choices are amongst the most important actions for the prevention of cardiometabolic diseases. Despite this, it appears difficult to convince consumers to select more nutritious foods. Furthermore, the development and production of healthier foods do not always lead to economic profits for the agro-food sector. Most dietary recommendations for the general population represent a "one-size-fits-all approach" which does not necessarily ensure that everyone has adequate exposure to health-promoting constituents of foods. Indeed, we now know that individuals show a high variability in responses when exposed to specific nutrients, foods, or diets. Purpose This review aims to highlight our current understanding of inter-individual variability in response to dietary bioactives, based on the integration of findings of the COST Action POSITIVe. We also evaluate opportunities for translation of scientific knowledge on inter-individual variability in response to dietary bioactives, once it becomes available, into practical applications for stakeholders, such as the agro-food industry. The potential impact from such applications will form an important impetus for the food industry to develop and market new high quality and healthy foods for specific groups of consumers in the future. This may contribute to a decrease in the burden of diet-related chronic diseases. Key messages Individual differences in ADME (Absorption, Digestion, Metabolism and Excretion) is believed to underpin much of the inter-individual variation in responses. Recent developments in the area of food metabolome databases and fast improvements in innovative metabotyping technologies hold great promise for improved profiling of dietary intake, exposure to individual ingredients, foods and dietary patterns, as well as our ability to identify individual responsiveness. The food industry needs well-defined population clusters or targets in order to be able to design "personalized products". There are indeed excellent industrial opportunities for foods that modulate gut microbiota, and thereby enable the delivery of food bioactive metabolites. It is currently not clear whether knowledge on individual nutrient needs, based on genetic or metagenomic data, would affect long-term dietary and health behaviours. Data to support the development of dietary recommendations may need to be generated by new n-of-1-based study designs in the future.
Ämnesord
- SAMHÄLLSVETENSKAP -- Annan samhällsvetenskap -- Tvärvetenskapliga studier inom samhällsvetenskap (hsv//swe)
- SOCIAL SCIENCES -- Other Social Sciences -- Social Sciences Interdisciplinary (hsv//eng)
- LANTBRUKSVETENSKAPER -- Lantbruksvetenskap, skogsbruk och fiske -- Livsmedelsvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Agriculture, Forestry and Fisheries -- Food Science (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Nyckelord
- Healthy diet
- Food industry
- Inter-individual variability in responses
- Cardiometabolic diseases
- Stakeholders
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Till lärosätets databas
- Av författaren/redakt...
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de Roos, Baukje
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Aura, Anna-Marja
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Bronze, Maria
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Cassidy, Aedin
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Garcia Conesa, M ...
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Gibney, Eileen R ...
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visa fler...
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Greyling, Arno
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Kaput, Jim
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Kerem, Zohar
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Knezevic, Nada
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Kroon, Paul
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Landberg, Rikard ...
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Manach, Claudine
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Milenkovic, Drag ...
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Rodriguez-Mateos ...
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Tomas-Barberan, ...
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van de Wiele, To ...
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Morand, Christin ...
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visa färre...
- Om ämnet
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- SAMHÄLLSVETENSKAP
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SAMHÄLLSVETENSKA ...
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och Annan samhällsve ...
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och Tvärvetenskaplig ...
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- LANTBRUKSVETENSKAPER
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LANTBRUKSVETENSK ...
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och Lantbruksvetensk ...
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och Livsmedelsvetens ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Näringslära
- Artiklar i publikationen
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European Journal ...
- Av lärosätet
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Chalmers tekniska högskola