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Synthesis and chara...
Synthesis and characterization of glycol chitosan coated selenium nanoparticles acts synergistically to alleviate oxidative stress and increase ginsenoside content in Panax ginseng
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- Abid, Suleman (författare)
- Kyung Hee University
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- Kaliraj, Lalitha (författare)
- Kyung Hee University
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- Rahimi, Shadi, 1982 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Kim, Yeon Ju (författare)
- Kyung Hee University
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- Yang, Deok Chun (författare)
- Kyung Hee University
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- Kang, Se Chan (författare)
- Kyung Hee University
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- Balusamy, Sri Renukadevi (författare)
- Sejong University
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(creator_code:org_t)
- Elsevier BV, 2021
- 2021
- Engelska.
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Ingår i: Carbohydrate Polymers. - : Elsevier BV. - 0144-8617. ; 267
- Relaterad länk:
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https://doi.org/10.1...
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https://research.cha...
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Abstract
Ämnesord
Stäng
- The objective of the present study is synthesis of glycol chitosan coated selenium nanoparticles (GC-Se NPs) and evaluation of oxidative stress and ginsenoside accumulation in P. ginseng C. A. Meyer. We synthesized (Se NPs and GC-Se NPs) and characterized using various spectroscopic analyses. The highest concentration (20 mg L−1) of GC-Se NPs induced moderate ROS (O2[rad]− and H2O2) accumulation and upregulation of PgSOD and PgCAT showing good biocompatibility and less toxicity at the highest concentration. Furthermore, ginsenoside biosynthetic pathway genes (PgHMGR, PgSS, PgSE, PgDDS) also showed significant upregulation upon 20 mg L−1 GC-Se NPs treatment. At 20 mg L−1 GC-Se NPs treatment, ginsenoside accumulated upto 217.47 mg/mL and 169.86 mg/mL mainly due to the increased proportion of Rb1 and Re ginsenosides. Altogether, our results suggested that ecofriendly conjugation of GC with Se NPs could be used as a bio fortifier to enhance the ginsenoside profile and to increase the quality of ginseng roots.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Industriell bioteknik -- Bioteknisk apparatteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Industrial Biotechnology -- Bioengineering Equipment (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Miljöbioteknik -- Vattenbehandling (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Environmental Biotechnology -- Water Treatment (hsv//eng)
Nyckelord
- Glycol chitosan nanoparticles
- Selenium nanoparticles
- Antioxidant enzymes
- Chitosan
- Ginsenoside
- Oxidative stress
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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