A comparison between the transfer function of ABP to ICP and compensatory reserve index in TBI

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• BACKGROUND: The transfer functions which map the arterial blood pressure to the intracranial pressure and the compensatory reserve index have been investigated by various groups to evaluate the brain compliance of patients with traumatic brain injury. The focus of this study has been to assess the capability of both the above mentioned methods to monitor the intracranial compliance in patients suffering from brain swelling. MATERIALS AND METHODS: Clinical data was collected from sixteen traumatic brain injury patients and split into 4 min segments. For each segment, both the magnitude of the empirical transfer function at the fundamental cardiac frequency and the compensatory reserve index were extracted. FINDINGS: The mean values of the compensatory reserve index and the magnitude of the transfer function which scored higher than 0.7 and 0.1 respectively were recorded for all patients suffering from brain swelling. By comparing the histogram of the magnitude of the transfer function at the fundamental cardiac frequency with the histogram of the compensatory reserve index for all patients, a positive correlation between the mean values and a negative correlation among their variances were observed. The linear correlation between the mean values was estimated at r = 0.82 (p

Ämnesord

NATURVETENSKAP  -- Data- och informationsvetenskap (hsv//swe)

NATURAL SCIENCES  -- Computer and Information Sciences (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

Nyckelord

blood pressure

aged

middle aged

signal processing

intracranial pressure

Time Factors

comparative study

brain circulation

article

Computer-Assisted

time

physiology

Humans

Young Adult

pathophysiology

hospitalization

brain injury

Cerebrovascular Circulation

human

male

Brain Injuries

Signal Processing

Severity of Illness Index

adolescent

female

adult

Adolescent

Adult

Aged

Blood Pressure

physiology

Brain Injuries

physiopathology

Cerebrovascular Circulation

Female

Humans

Intracranial Pressure

Male

Middle Aged

Severity of Illness Index

Signal Processing

Computer-Assisted

Time Factors

Young Adult

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