Sökning: id:"swepub:oai:research.chalmers.se:fec1a53c-5979-4b24-9b64-f30689d46799" >
Establishing a plat...
Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism
-
- Chen, Yun, 1978 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
-
Daviet, L. (författare)
-
Schalk, M. (författare)
-
visa fler...
-
- Siewers, Verena, 1976 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
-
- Nielsen, Jens B, 1962 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
-
visa färre...
-
(creator_code:org_t)
- Elsevier BV, 2013
- 2013
- Engelska.
-
Ingår i: Metabolic Engineering. - : Elsevier BV. - 1096-7176 .- 1096-7184. ; 15:1, s. 48-54
- Relaterad länk:
-
http://dx.doi.org/10...
-
visa fler...
-
https://doi.org/10.1...
-
https://research.cha...
-
visa färre...
Abstract
Ämnesord
Stäng
- Production of fuels and chemicals by industrial biotechnology requires efficient, safe and flexible cell factory platforms that can be used for production of a wide range of compounds. Here we developed a platform yeast cell factory for efficient provision of acetyl-CoA that serves as precursor metabolite for a wide range of industrially interesting products. We demonstrate that the platform cell factory can be used to improve the production of alpha-santalene, a plant sesquiterpene that can be used as a perfume by four-fold. This strain would be a useful tool to produce a wide range of acetyl-CoA-derived products.
Ämnesord
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
Nyckelord
- Acetyl-CoA
- Saccharomyces cerevisiae
- saccharomyces-cerevisiae
- pyruvate-decarboxylase
- expression
- Cell factory
- growth-rate
- precursor
- synthetase
- alpha-Santalene
- sequence
- glucose
- transcription
- fermentation
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas