Sökning: id:"swepub:oai:researchportal.hkr.se/admin:publications/433f05b7-e454-48a8-b121-0cd1e5dec964" >
High risk of develo...
High risk of developing dementia in Parkinson's disease : a Swedish registry-based study
-
- Åström, Daniel Oudin (författare)
- H. Lundbeck A/S
-
- Simonsen, Jacob (författare)
- H. Lundbeck A/S
-
- Raket, Lars Lau (författare)
- Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,H. Lundbeck A/S
-
visa fler...
-
- Sgarbi, Simona (författare)
- H. Lundbeck A/S
-
- Hellsten, Johan (författare)
- H. Lundbeck A/S
-
- Hagell, Peter (författare)
- Kristianstad University
-
- Norlin, Jenny M (författare)
- The Swedish Institute for Health Economics,Institutet För Hälso- Och Sjukvårdsekonomi,IHE – The Swedish Institute for Health Economics
-
- Kellerborg, Klas (författare)
- The Swedish Institute for Health Economics,Institutet För Hälso- Och Sjukvårdsekonomi,IHE – The Swedish Institute for Health Economics
-
- Martinez-Martin, Pablo (författare)
- Area of Applied Epidemiology, Center for Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid,Area of Applied Epidemiology, Center for Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid,CIBER Enfermedades Neurodegenerativas (CIBERNED)
-
- Odin, Per (författare)
- Lund University,Lunds universitet,Restorative Parkinson Unit,Forskargrupper vid Lunds universitet,Lund University Research Groups
-
visa färre...
-
H Lundbeck A/S Klinisk minnesforskning (creator_code:org_t)
- Nature Publishing Group, 2022
- 2022
- Engelska.
-
Ingår i: Scientific Reports. - : Nature Publishing Group. - 2045-2322. ; 12:1
- Relaterad länk:
-
https://researchport... (primary) (free)
-
visa fler...
-
https://doi.org/10.1... (free)
-
http://dx.doi.org/10... (free)
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Dementia have substantial negative impact on the affected individual, their care partners and society. Persons living with Parkinson's disease (PwP) are also to a large extent living with dementia. The aim of this study is to estimate time to dementia in PD using data from a large quality register with access to baseline clinical and patient reported data merged with Swedish national health registries. Persons with Parkinson's disease in the Swedish Neuro Registries/Parkinson's Disease Swedish PD Registry (PARKreg) in Sweden were included and linked to national health registries and matched by sex and age to controls without PD. Time to dementia was analysed with Cox regression models assuming proportional hazards, with time since diagnosis as the underlying time variable. In this large prospective cohort study, PwP had approximately four times higher risk of developing dementia as compared to age and sex-matched controls, a finding which remained after adjusting for potential confounders. The present resultsunderline the high risk of dementia in PD and further emphasize the importance of developing symptomatic and ultimately disease modifying strategies to counteract this part of the non-motor symptomatology in PD.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Åström, Daniel O ...
-
Simonsen, Jacob
-
Raket, Lars Lau
-
Sgarbi, Simona
-
Hellsten, Johan
-
Hagell, Peter
-
visa fler...
-
Norlin, Jenny M
-
Kellerborg, Klas
-
Martinez-Martin, ...
-
Odin, Per
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Neurologi
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Geriatrik
- Artiklar i publikationen
-
Scientific Repor ...
- Av lärosätet
-
Högskolan Kristianstad
-
Lunds universitet