- Førland, Marthe Gurine, et al.
Validation of a new assay for α-synuclein detection in cerebrospinal fluid.
Ingår i: Clinical chemistry and laboratory medicine. - 1437-4331. ; 55:2
- Abnormal α-synuclein aggregation and deposition is the pathological hallmark of Parkinson's disease (PD) and dementia with Lewy bodies (DLB), but is also found in Alzheimer disease (AD). Therefore, there is a gaining interest in α-synuclein in cerebrospinal fluid (CSF) as potential biomarker for these neurodegenerative diseases. To broaden the available choices of α-synuclein measurement in CSF, we developed and validated a new assay for detecting total α-synuclein.