| 1. |
- Schölin, Anna, et al.
(författare)
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Islet antibodies and remaining beta-cell function 8 years after diagnosis of diabetes in young adults : a prospective follow-up of the nationwide Diabetes Incidence Study in Sweden
- 2004
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Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 255:3, s. 384-391
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- ObjectivesTo establish the prevalence of remaining β-cell function 8 years after diagnosis of diabetes in young adults and relate the findings to islet antibodies at diagnosis and 8 years later.DesignPopulation-based cohort study.SettingNationwide from all Departments of Medicine and Endocrinology in Sweden.SubjectsA total of 312 young (15–34 years old) adults diagnosed with diabetes during 1987–88.Main outcome measurePlasma connecting peptide (C-peptide) 8 years after diagnosis. Preserved β-cell function was defined as measurable C-peptide levels. Three islet antibodies – cytoplasmic islet cell antibodies (ICA), glutamic acid decarboxylase antibodies and tyrosine phosphatase antibodies – were measured.ResultsAmongst 269 islet antibody positives (ab+) at diagnosis, preserved β-cell function was found in 16% (42/269) 8 years later and these patients had a higher body mass index (median 22.7 and 20.5 kg m−2, respectively; P = 0.0003), an increased frequency of one islet antibody (50 and 24%, respectively; P = 0.001), and a lower prevalence of ICA (55 and 6%, respectively; P = 0.007) at diagnosis compared with ab+ without remaining β-cell function. Amongst the 241 patients without detectable β-cell function at follow-up, 14 lacked islet antibodies, both at diagnosis and at follow-up.ConclusionsSixteen per cent of patients with autoimmune type 1 diabetes had remaining β-cell function 8 years after diagnosis whereas 5.8% with β-cell failure lacked islet autoimmunity, both at diagnosis and at follow-up.
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| 2. |
- Schölin, Anna, et al.
(författare)
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Normal weight promotes remission and low number of islet antibodies prolong the duration of remission in Type 1 diabetes
- 2004
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Ingår i: Diabetic Medicine. - : Wiley. - 0742-3071 .- 1464-5491. ; 21:5, s. 447-455
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Aim To identify clinical, immunological and biochemical factors that predict remission, and its duration in a large cohort of young adults with Type 1 diabetes mellitus (DM).Methods In Sweden, 362 patients (15–34 years), classified as Type 1 DM were included in a prospective, nation-wide population-based study. All patients were followed at local hospitals for examination of HbA1c and insulin dosage over a median period after diagnosis of 5 years. Duration of remission, defined as an insulin maintenance dose ≤ 0.3 U/kg/24 h and HbA1c within the normal range, was analysed in relation to characteristics at diagnosis.Results Remissions were seen in 43% of the patients with a median duration of 8 months (range 1–73). Sixteen per cent had a remission with a duration > 12 months. Among patients with antibodies (ab+), bivariate analysis suggested that adult age, absence of low BMI, high plasma C-peptide concentrations, lack of ketonuria or ketoacidosis at diagnosis and low insulin dose at discharge from hospital were associated with a high possibility of achieving remission. Multiple regression showed that normal weight (BMI of 20–24.9 kg/m2) was the only factor that remained significant for the possibility of entering remission. In survival analysis among ab+ remitters, a low number of islet antibodies, one or two instead of three or four, were associated with a long duration of remissions.Conclusion In islet antibody-positive Type 1 DM, normal body weight was the strongest factor for entering remission, whilst a low number of islet antibodies was of importance for the duration.
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| 4. |
- Landström, Inger, 1954-
(författare)
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Mellan samtid och tradition : folkhögskolans identitet i kursutbudets yrkesinriktning
- 2004
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In this thesis the vocational orientation of the courses offered - as an expression of the folk high school's self-identity- is analysed. The point of departure was that what the folk high school do, is a way to show what it wants to be and, therefore, reflects what it is. Focus is on how the folk high school meets with contemporary tasks and demands in different areas of society. The research objects are, the folk high school as type of school (a total of 147 schools) and a sample of ten individual schools with different ownership. The study is about what the offered courses reveal about the folk high school's reflections and conclusions as regards its future activities in relation to its history and contemporary society.The theoretical framework of the thesis is built on the sociologist Anthony Giddens 'Theory of Structuration' and the concepts of structure and agency. Reflections about the surrounding world and the contributions the schools' want to make in society is assumed to result in a more or less conscious strategy for the future, the folk high school's course politics as it is expressed in action. The identity has been interpreted in vocational roles as they appear in course contents. The word 'vocation' is used in almost the same sense as Giddens defines 'work'.Self-identity was analysed from three different kinds of texts and with one question for each. In the first perspective focus is on official investigations and political decisions, in the period 1970-2000. What role in society is imposed upon the folk high school in contemporary educational policies? In the second perspective all courses offered at all folk high schools in 1972 and 2000 are studied, in order to present a picture of the overall pattern of vocational orientation. In the third perspective the course politics of the ten selected folk high schools are investigated, from the start of the respective schools, and in relation to what each school thinks it 'is'- with different owners and in its particular geographical situation.One overriding conclusion is that the characteristics that make the identity of the folk high school seem unclear and paradoxical are the very same that constitute the self-identity of the folk high school as being complex and multifaceted. The self-identity seems paradoxical when the vocational orientation presents itself as both preserving traditions and answering to today's needs. In other words, the school 'does what it has always done' (is conservative) and at the same time 'captures new needs and tasks' (is flexible).The folk high school's role and uniqueness in what they actually do can be understood as what I have called 'contemporaneous civic functionaries'. Their profiles emerge when flexibility is based on history. I want to designate 'existential rationality' to the motivating mechanism that seems to at the same time force changes and lean on own experiences. Expressing contemporary self-identity is grounded in the individual tradition as motivationbased values, cultural and geographic conditions.
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| 6. |
- Borg, Kajsa
(författare)
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Slöjdämnet : intryck, uttryck, avtryck
- 2001
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The purpose of this study was to illuminate and question the school subject Sloyd from the perspective of the former pupils, now adult persons The empirical investigations cover interviews with subject teachers and adult, focusing their memories of the Sloyd subject in the compulsory school. The analysis shows that the impression of the qualities of the subject is connected to the pupil's personal and bodily experience of the work process in textile, wood or metal material. The creative work generates feelings of pleasure and fulfilment, which seems to correspond to basic needs, ahich most people recognize. The Sloyd subject can be characterized by four aspects: the manual, the aestethic, the communicative and the theoretical.
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| 7. |
- Edvinsson, Sören, et al.
(författare)
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Urban mortality in Sweden during the 19th century
- 2000
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Ingår i: Population Dynamics during Industrialization. - Umeå : Umeå universitet. - 9171914218 ; , s. 39-81
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 8. |
- Hansen, Peo, 1966-
(författare)
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Europeans only? : essays on identity politics and the European Union
- 2000
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The chief preoccupation of the dissertation revolves around the European Union's project of calling forth a collective sense of "European identity" amongst people in the Union. It focuses specifically on how the European Union's identity politics plays out once the ethnic minorities with immigrant background now living in the Union are brought into view. The main purpose can be described as twofold; involving, firstly, a mapping and examination of how the EU construes and defines the identity it seeks to mobilize, and, secondly, a thorough discussion of the types of consequences or implications that stem from this endeavour.In demonstrating the strong tendency on part of the EU to articulate a common identity for the Union in ethno-cultural terms — whereby the EU is conceived as primarily a cultural community whose members are said to share the same origin, cultural heritage, religion and history — the study goes to great length in discussing the excluding implications that an ethno-cultural identity politics gives rise to. The dissertation argues that such an ethno-cultural disposition partly must be seen in light of the European Union's gradual adjustment to a largely neoliberal order; an order which has worked restraining on the feasibility of a social and political articulation of identity and citizenship in the Union.An introductory chapter outlines the discourse theoretical approach which guides the analyses in five essays. The essays mainly explore how the European Union's discourse on identity manifests in various policy areas - immigration, citizenship and education - all of which in one way or another address the issues of culture, the multicultural society, ethnic exclusion, racism and the situation for ethnic minorities and migrants. The complex of problems concerning ethnic, cultural and social exclusion in today's European Union thus constitutes a central theme engaged with throughout the dissertation.
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