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Träfflista för sökning "swepub ;lar1:(kau);srt2:(1990-1999)"

Search: swepub > Karlstad University > (1990-1999)

  • Result 1-10 of 2314
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1.
  • Arvidsson, Ann-Kristin, et al. (author)
  • Tyr-716 in the platelet-derived growth factor beta-receptor kinase insertis involved in GRB2 binding and Ras activation
  • 1994
  • In: Molecular and Cellular Biology. - : American Society for Microbiology. - 0270-7306 .- 1098-5549. ; 14:10, s. 6715-6726
  • Journal article (peer-reviewed)abstract
    • Ligand stimulation of the platelet-derived growth factor (PDGF) beta-receptor leads to activation of its intrinsic tyrosine kinase and autophosphorylation of the intracellular part of the receptor. The autophosphorylated tyrosine residues mediate interactions with downstream signal transduction molecules and thereby initiate different signalling pathways. A pathway leading to activation of the GTP-binding protein Ras involves the adaptor molecule GRB2. Here we show that Tyr-716, a novel autophosphorylation site in the PDGF beta-receptor kinase insert, mediates direct binding of GRB2 in vitro and in vivo. In a panel of mutant PDGF beta-receptors, in which Tyr-716 and the previously known autophosphorylation sites were individually mutated, only PDGFR beta Y716F failed to bind GRB2. Furthermore, a synthetic phosphorylated peptide containing Tyr-716 bound GRB2, and this peptide specifically interrupted the interaction between GRB2 and the wild-type receptor. In addition, the Y716(P) peptide significantly decreased the amount of GTP bound to Ras in response to PDGF in permeabilized fibroblasts as well as in porcine aortic endothelial cells expressing transfected PDGF beta-receptors. The mutant PDGFR beta Y716F still mediated activation of mitogen-activated protein kinases and an increased DNA synthesis in response to PDGF, indicating that multiple signal transduction pathways transduce mitogenic signals from the activated PDGF beta-receptor.
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  • Fjelstad, Jens, 1971-, et al. (author)
  • Equivalence of Chern-Simons gauge theory and WZNW model using a BRST symmetry
  • 1999
  • In: Physics Letters B. - : Elsevier. - 0370-2693 .- 1873-2445. ; 466:2-4, s. 227-233
  • Journal article (peer-reviewed)abstract
    • The equivalence between the Chern-Simons gauge theory on a three-dimensional manifold with boundary and the WZNW model on the boundary is established in a simple and general way using the BRST symmetry. Our approach is based on restoring gauge invariance of the Chern-Simons theory in the presence of a boundary. This gives a correspondence to the WZNW model that does not require solving any constraints, fixing the gauge or specifying boundary conditions.
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  • Grenholm, Cristina (author)
  • Romans Interpreted : A Comparative Analysis of the Commentaries of Barth, Nygren, Cranfield and Wilckens on Paul´s Epistle to the Romans
  • 1990
  • Doctoral thesis (other academic/artistic)abstract
    • This thesis deals with the problem of how to explain different interpretations of Paul's Epistle to the Romans in the four contemporary commentaries of Karl Barth, Anders Nygren, Charles Cranfield and Ulrich Wilckens. The purpose of this study is to put forward and analyse the different interpretations given by the commentators and to examine some ways in which these differences may be explained.The differences analysed primarily concern central theological issues. A detailed description of the four different interpretations of Romans is given on three levels: (i) concerning Romans 7, (ii) concerning some theological themes in Romans and (iii) concerning some general remarks on Romans which are important for the interpretation of the Epistle.Different kinds of interpretations are defined by the development of a theory of interpretation which focuses on the arguments supporting the commentators' choices of interpretation. The different interpretations of Romans are explained by reference to the commentators' pursuit of different combinations of kinds of interpretations and by the contents of their arguments. Explanations are also found in their pursuit of different combinations of purposes. Their views of the contents of Christian faith, revelation and the Bible also explain the different interpretations. Special attention is paid to a fundamental lack of clarity in the commentaries concerning the relation between reconstructive and constructive interpretations, the problem of application.The commentaries are used as examples of biblical interpretation to arrive at a detailed knowledge of the complex process of interpretation. Distinctions are developed concerning kinds of interpretations, kinds of purposes and different views of revelation and the Bible
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  • Result 1-10 of 2314
Type of publication
journal article (805)
reports (562)
conference paper (318)
book chapter (249)
other publication (171)
book (95)
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doctoral thesis (62)
licentiate thesis (23)
review (20)
editorial collection (5)
artistic work (3)
editorial proceedings (3)
research review (1)
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Type of content
peer-reviewed (1241)
other academic/artistic (758)
pop. science, debate, etc. (315)
Author/Editor
Starrin, Bengt (89)
Edvardsson, Bo (74)
Nilsson, Anders G. (43)
Larsson, G (43)
Hagquist, Curt (43)
Micheletti, Michele (41)
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Greenberg, Larry (39)
Burnett, Robert (38)
Gonäs, Lena (31)
Miles, Lee (31)
Wilde Larsson, Bodil (30)
van Stam, Jan (30)
Forsberg, Erik (28)
Gustafsson, Anders (27)
Berger, Sune (26)
Norling, Per (25)
Renck, Barbro (24)
Järnström, Lars (23)
Blom, Thomas (23)
Eriksson, Bengt G (23)
Pérez Prieto, Héctor (22)
De Schryver, FC (22)
Bergman, Eva (21)
Månsson, Bengt (21)
Andersson, Kerstin (20)
Athlin, Elsy, 1945- (20)
Magnusson, Kjell (19)
Andersson, Lennart (19)
Athlin, Elsy (19)
Karlsson, Jan Ch (19)
Sundström, Birgitta (19)
Jakobsson, Andreas (18)
Nordström, Gun (18)
Boström, Hans-Olof (18)
Schmitz, Monika (17)
Fredriksson, Odd (17)
Linnarud, Moira (17)
Jansson, André (17)
Norlander, Torsten (17)
Bladh, Gabriel (17)
Sundqvist, Martin (17)
Mc Ewen, Birgitta, 1 ... (17)
Nyberg, Lars (16)
Arnqvist, Anders (16)
Leidhammar, Börje (16)
Dahlström, Margareta ... (16)
Hiltunen, Arto (16)
Larsson, Patrik (16)
Scherp, Hans-Åke (16)
Reihl, B. (16)
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University
Karlstad University  (2314)Undo refine
Uppsala University (47)
University of Gothenburg (22)
Stockholm University (22)
Karolinska Institutet (19)
Örebro University (16)
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Swedish National Defence College (12)
Linköping University (9)
Luleå University of Technology (5)
Lund University (4)
Linnaeus University (4)
Umeå University (2)
Royal Institute of Technology (2)
University of Gävle (2)
Mid Sweden University (2)
Södertörn University (2)
University of Borås (2)
VTI - The Swedish National Road and Transport Research Institute (2)
Jönköping University (1)
Chalmers University of Technology (1)
Marie Cederschiöld högskola (1)
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Language
English (1283)
Swedish (1018)
Norwegian (5)
Undefined language (4)
Russian (3)
Finnish (1)
Research subject (UKÄ/SCB)
Social Sciences (975)
Natural sciences (431)
Medical and Health Sciences (304)
Humanities (204)
Engineering and Technology (149)

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