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Sökning: swepub > Konferensbidrag > Göteborgs universitet > Lunds universitet > (2005-2009)

  • Resultat 1-10 av 11
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1.
  • Wendtland Edslev, Pernille, et al. (författare)
  • Age and Prognosis in Pediatric AML
  • 2008
  • Ingår i: Blood. - 1528-0020 .- 0006-4971. ; 112:11
  • Konferensbidrag (refereegranskat)
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  • Ruschin, Mark, et al. (författare)
  • Shape determination of microcalcifications in simulated digital mammography images with varying pixel size
  • 2005
  • Ingår i: Proceedings of the SPIE - The International Society for Optical Engineering. - : SPIE. - 0277-786X .- 1996-756X. ; 5749, s. 288-299
  • Konferensbidrag (refereegranskat)abstract
    • The purpose of this work was to study how the pixel size of digital detectors can affect shape determination of microcalcifications in mammography. Screen-film mammograms containing microcalcifications clinically proven to be indicative of malignancy were digitised at 100 lines/mm using a high-resolution Tango drum scanner. Forty microcalcifications were selected to cover an appropriate range of sizes, shapes and contrasts typically found of malignant cases. Based on the measured MTF and NPS of the combined screen-film and scanner system, these digitised images were filtered to simulate images acquired with a square sampling pixel size of 10 μm × 10 μm and a fill factor of one. To simulate images acquired with larger pixel sizes, these finely sampled images were re-binned to yield a range of effective pixel sizes from 20 μm up to 140 μm. An alternative forced-choice (AFC) observer experiment was conducted with eleven observers for this set of digitised microcalcifications to determine how pixel size affects the ability to discriminate shape. It was found that observer score increased with decreasing pixel size down to 60 μm (p<0.01), at which point no significant advantage was obtained by using smaller pixel sizes due to the excessive relative noise-per-pixel. The relative gain in shape discrimination ability at smaller pixel sizes was larger for microcalcifications that were smaller than 500 μm and circular
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  • Timberg, Pontus, et al. (författare)
  • Optimization of image quality in breast tomosynthesis using lumpectomy and mastectomy specimens
  • 2007
  • Ingår i: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. - : SPIE. - 1042-4687 .- 1605-7422. ; 6510:PART 2, s. 1379-1386
  • Konferensbidrag (refereegranskat)abstract
    • The purpose of this study was to determine how image quality in breast tomosynthesis (BT) is affected when acquisition modes are varied, using human breast specimens containing malignant tumors and/or microcalcifications. Images of thirty-one breast lumpectomy and mastectomy specimens were acquired on a BT prototype based on a Mammomat Novation (Siemens) full-field digital mammography system. BT image acquisitions of the same specimens were performed varying the number of projections, angular range, and detector signal collection mode (binned and non-binned in the scan direction). An enhanced filtered back projection reconstruction method was applied with constant settings of spectral and slice thickness filters. The quality of these images was evaluated via relative visual grading analysis (VGA) human observer performance experiments using image quality criteria. Results from the relative VGA study indicate that image quality increases with number of projections and angular range. A binned detector collecting mode results in less noise, but reduced resolution of structures. Human breast specimens seem to be suitable for comparing image sets in BT with image quality criteria.
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  • Resultat 1-10 av 11

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