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1.
  • Flygare, Erik, et al. (författare)
  • Utvärdering av metoder mot mobbning
  • 2011
  • Rapport (övrigt vetenskapligt)abstract
    • Denna utvärdering ger besked om insatser och arbetssätt som effektivt förebygger och åtgärdar mobbning. Utvärderingen är unik genom att den omfattar stora mängder data, både kvalitativa och kvantitativa från 39 skolor, att enskilda individers utsatthet följs upp vid tre tillfällen och att den omfattar flera program samtidigt.Resultaten visar bland annat att olika insatser har olika effekt för pojkar och flickor samt olika effekt beroende på om mobbningen är social eller fysisk. Den visar också att ingen enskild insats har dramatiskt positiva effekter. För att en skola ska lyckas förebygga och åtgärda mobbning krävs ett systematiskt arbete och en kombination av insatser. Åtta namngivna program som används mot mobbning har ingått i utvärderingen: Farstametoden, Friends, Lions Quest, Olweusprogrammet, SET - Social och emotionell träning, Skolkomet, Skolmedling samt Stegvis. I utvärderingens fristående metodfördjupning Utvärdering av metoder mot mobbning. Metodappendix och bilagor till rapport 353, (endast publicerad som pdf ) redovisar forskarna utförligt utvärderingens design och redogör för tillvägagångssättet vid datainsamling och analys.
2.
  • Lahermo, Päivi, et al. (författare)
  • A quality assessment survey of SNP genotyping laboratories
  • 2006
  • Ingår i: Human Mutation. - 1059-7794. ; 27:7, s. 711-714
  • Tidskriftsartikel (övrigt vetenskapligt)abstract
    • To survey the quality of SNP genotyping, a joint Nordic quality assessment (QA) round was organized between 11 laboratories in the Nordic and Baltic countries. The QA round involved blinded genotyping of 47 DNA samples for 18 or six randomly selected SNPs. The methods used by the participating laboratories included all major platforms for small- to medium-size SNP genotyping. The laboratories used their standard procedures for SNP assay design, genotyping, and quality control. Based on the joint results from all laboratories, a consensus genotype for each DNA sample and SNP was determined by the coordinator of the survey, and the results from each laboratory were compared to this genotype. The overall genotyping accuracy achieved in the survey was excellent. Six laboratories delivered genotype data that were in full agreement with the consensus genotype. The average accuracy per SNP varied from 99.1 to 100% between the laboratories, and it was frequently 100% for the majority of the assays for which SNP genotypes were reported. Lessons from the survey are that special attention should be given to the quality of the DNA samples prior to genotyping, and that a conservative approach for calling the genotypes should be used to achieve a high accuracy.
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3.
  • Adams, Robin, et al. (författare)
  • What is the word for 'Engineering' in Swedish : Swedish students conceptions of their discipline
  • 2007
  • Rapport (övrigt vetenskapligt)abstract
    • Engineering education in Sweden – as in the rest of the world – is experiencing a decline in student interest. There are concerns about the ways in which students think about engineering education, why they join an academic programme in engineering, and why they persist in their studies. In this context the aims of the Nationellt ämnesdidaktiskt Centrum för Teknikutbildning i Studenternas Sammanhang project (CeTUSS) is to investigate the student experience and to identify and support a continuing network of interested researchers, as well as in building capacity for disciplinary pedagogic investigation.The Stepping Stones project brings together these interests in a multi-researcher, multi-institutional study that investigates how tudents and academic staff perceive engineering in Sweden and in Swedish education. The first results of that project are reported here. As this study is situated uniquely in Swedish education, it allows for exploration of “a Swedish perspective” on conceptions of engineering. The Stepping Stones project was based on a model of research capacity-building previously instantiated in the USA and Australia (Fincher & Tenenberg, 2006).
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4.
  • Daşu, Alexandru, et al. (författare)
  • Treatment modelling : the influence of micro-environmental conditions.
  • 2008
  • Ingår i: Acta Oncol. - 1651-226X. ; 47:5, s. 896-905
  • Tidskriftsartikel (övrigt vetenskapligt)abstract
    • The interest in theoretical modelling of radiation response has grown steadily from a fast method to estimate the gain of new treatment strategies to an individualisation tool that may be used as part of the treatment planning algorithms. While the advantages of biological optimisation of plans are obvious, accurate theoretical models and realistic information about the micro-environmental conditions in tissues are needed. This paper aimed to investigate the clinical implications of taking into consideration the details of the tumour microenvironmental conditions. The focus was on the availability of oxygen and other nutrients to tumour cells and the relationship between cellular energy reserves and DNA repair ability as this is thought to influence the response of the various hypoxic cells. The choice of the theoretical models for predicting the response (the linear quadratic model or the inducible repair model) was also addressed. The modelling performed in this project has shown that the postulated radiobiological differences between acute and chronic hypoxia have some important clinical implications which may help to understand the mechanism behind the current success rates of radiotherapy. The results also suggested that it is important to distinguish between the two types of hypoxia in predictive assays and other treatment simulations.
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5.
  • Daşu, Alexandru, et al. (författare)
  • Vascular oxygen content and the tissue oxygenation--a theoretical analysis.
  • 2008
  • Ingår i: Med Phys. - 0094-2405. ; 35:2, s. 539-45
  • Tidskriftsartikel (övrigt vetenskapligt)abstract
    • Several methods exist for evaluating tumor oxygenation as hypoxia is an important prognostic factor for cancer patients. They use different measuring principles that highlight various aspects of oxygenation. The results could be empirically correlated, but it has been suspected that there could be discordances in some cases. This study describes an analysis of the relationship between vascular and tissue oxygenations. Theoretical simulation has been employed to characterize tissue oxygenations for a broad range of distributions of intervessel distances and vascular oxygenations. The results were evaluated with respect to the implications for practical measurements of tissue oxygenations. The findings showed that although the tissue oxygenation is deterministically related to vascular oxygenation, the relationship between them is not unequivocal. Variability also exists between the fractions of values below the sensitivity thresholds of various measurement methods which in turn could be reflected in the power of correlations between results from different methods or in the selection of patients for prognostic studies. The study has also identified potential difficulties that may be encountered at the quantitative evaluation of the results from oxygenation measurements. These could improve the understanding of oxygenation measurements and the interpretation of comparisons between results from various measurement methods.
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6.
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7.
  • Westlund, Hans, et al. (författare)
  • Kan hela Sverige leva som Gnosjö?
  • 2008
  • Ingår i: Ska hela Sverige leva?. - Stockholm : Formas. - 978-91-540-6013-9 ; s. 217-228
  • Bokkapitel (övrigt vetenskapligt)abstract
    • Leder naturism till regional utveckling? Vad krävs för att bli en framgångsrik naturismföretagare? Och vad är det egentligen som lockar naturisterna? Attraktionerna på en turistort är själva kärnan, skriver Peter Fredman och Linda Lundmark. Men naturen kan vara en resurs för turismen bara om det samtidigt finns infrastruktur och ett lokalt utbud av produkter och service.
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8.
  • Ahlsson, Anders, et al. (författare)
  • A Swedish consensus on the surgical treatment of concomitant atrial fibrillation
  • 2012
  • Ingår i: Scandinavian Cardiovascular Journal. - Informa Healthcare. - 1401-7431. ; 46:4, s. 212-218
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • Atrial fibrillation (AF) is a common arrhythmia among patients scheduled for open heart surgery and is associated with increased morbidity and mortality. According to international guidelines, symptomatic and selected asymptomatic patients should be offered concomitant surgical AF ablation in conjunction with valvular or coronary surgery. The gold standard in AF surgery is the Cox Maze III ("cut-and-sew") procedure, with surgical incisions in both atria according to a specified pattern, in order to prevent AF reentry circuits from developing. Over 90% of patients treated with the Cox Maze III procedure are free of AF after 1 year. Recent developments in ablation technology have introduced several energy sources capable of creating nonconducting atrial wall lesions. In addition, simplified lesion patterns have been suggested, but results with these techniques have been unsatisfactory. There is a clear need for standardization in AF surgery. The Swedish Arrhythmia Surgery Group, represented by surgeons from all Swedish units for cardiothoracic surgery, has therefore reached a consensus on surgical treatment of concomitant AF. This consensus emphasizes adherence to the lesion pattern in the Cox Maze III procedure and the use of biatrial lesions in nonparoxysmal AF.
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9.
  • Stenhammar, Lars, 1939-, et al. (författare)
  • Small bowel biopsy in Swedish paediatric clinics.
  • 2002
  • Ingår i: Acta Paediatr. - 0803-5253. ; 91:10, s. 1126-9
  • Tidskriftsartikel (övrigt vetenskapligt)abstract
    • Aim: A correct diagnosis of coeliac disease, one of the most common chronic diseases in Swedish children, demands small bowel biopsy, which can be performed endoscopically or by means of a peroral capsule. Recently there was a debate among Swedish paediatric gastroenterologists, with some advocating the cessation of capsule biopsy in favour of endoscopic biopsies. To gain information on which to base a recommendation for which technique to use, the Swedish Working Group for Childhood Coeliac Disease was commissioned to carry out a national questionnaire study on current small bowel biopsy routines in Swedish paediatric clinics. Methods: A questionnaire concerning biopsy routines in the year 2000 was sent to all paediatric clinics performing biopsies. A reply was obtained from 39 of 40 clinics, covering 98% of the Swedish population. Results: Some 1400 biopsies were performed, 64% of which were capsule biopsies and 36% endoscopic. Three clinics performed all biopsies endoscopically and 11 clinics all via a capsule. At endoscopy all children were under deep sedation or full anaesthesia, while most children undergoing capsule biopsy were under light or deep sedation. The oxygen saturation was monitored during endoscopy but less often or never during routine capsule biopsy. The presence of the parents during biopsy varied according to the degree of sedation: at 97% of the clinics performing capsule biopsy on children under light sedation, the parents were present during the whole procedure, whereas no parents were present at clinics where the biopsy was performed endoscopically under anaesthesia. Conclusion: Compared with the results of a similar questionnaire concerning biopsy routines performed in the early 1990s, children are now more effectively sedated, Furthermore, there is an obvious trend from capsule towards endoscopic biopsy. Both the endoscopic and the capsule biopsy techniques are useful and satisfactory for obtaining small bowel mucosal samples providing that the children are effectively sedated. For practical and economic reasons the capsule biopsy technique will probably continue to be used, although to a lesser extent than today.
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10.
  • Rosvall, Per-Åke, 1970-, et al. (författare)
  • Pedagogic practice and influence in a Vehicle Programme class
  • 2011
  • Ingår i: Young people's influence and democratic education: Ethnographic studies in upper secondary schools. - The Tufnell Press. - 9781872767184 ; s. 92-111
  • Bokkapitel (övrigt vetenskapligt)abstract
    • The teaching and practice of democracy in schools might be considered particularly important in the present era as young people are spending increasing amounts of time in education. Upper secondary schools and universities are becoming more common post-school options than conventional workplaces. Consequently, the experience of democratic participation among the young people is strongly related to education spaces. Contemporary research shows the teaching of democratic values to typically emphasise individual freedom of choice and individual rights, at the expense of collective justice, political criticism and reflection. This risks leaving young people without guidance for how to exert influence both inside school and more generally. However, we lack knowledge about the relations between the content and organisation of teaching, and young people's attitudes and actions, as they typically constitute different research fields. This book attempts to help bridge this gap. Young people's influence and democratic education explores the teaching of democracy in school. In particular it relates to young peoples' responses and initiatives to change in formal education. Based on recent ethnographic investigations of Swedish upper secondary schools the book has been developed with a special focus on gender in relation to social background. Five differently gendered and classed upper secondary programmes were studied in detail. Theoretically, the book draws in particular on Bernsteinian and feminist perspectives. The book includes close individual analyses of the researched upper secondary classes as well as common presentations of previous research, theory and main empirical results. Central joint themes that are explored concerns teaching students to influence, student initiatives to exert influence, conditions for developing valued masculinities and femininities, the reproduction of hierarchical relations, and representations and relations of theory and practice.
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