Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "swepub ;lar1:(cth)"

Sökning: swepub > Chalmers tekniska högskola

Sortera/gruppera träfflistan
  • Gilbert, Jonas, 1968- (författare)
  • A Start for Implementing ORCID in the Swedish Research Information Infrastructure
  • 2013
  • Ingår i: ScieCom Info. - 1652-3202. ; 9:2
  • Tidskriftsartikel (populärvet., debatt m.m.)abstract
    • Texten presenterar i korthet det projekt kring författaridentifikatorer och publikationsdatabaser som Kungliga biblioteket finansierade under 2012 under projektledning av Stockholms universitetsbibliotek med deltagande av biblioteken vid Chalmers, Karolinska Institutet samt Malmö högskola.
  • Axelsson, Ann-Sofie, 1967-, et al. (författare)
  • Att etablera ett kollaboratorium inom biblioteks- och informationsvetenskap: behov och utmaningar från ett praktikerperspektiv
  • 2007
  • Ingår i: Svensk Biblioteksforskning. - 0284-4354. ; 16:1
  • Tidskriftsartikel (refereegranskat)abstract
    • This article describes a study that investigated the need for and challenges connected to the establishment of a collaboratory - a sociotechnical forum where information and other resources can be made accessible and used by practitioners within library and information science. In order to identify needs and challenges interviews were carried out with a number of practitioners at a number of different institutions. The results reveal that there is a need for a collaboratory in order to facilitate the sharing of personal knowledge “on demand”. It is of great importance that the collaboratory is well integrated with practitioner’s daily activities.
  • Dussauge, Isabelle, 1978-, et al. (författare)
  • Precursors of the IT Nation : Computer use and control in swedish society, 1955–1985
  • 2011
  • Ingår i: 3rd IFIP WG 9.7 Conference on History of Nordic Computing, HiNC 2010. - Springer-Verlag New York. - 9783642233142 ; s. 425-432
  • Konferensbidrag (refereegranskat)abstract
    • This paper is a presentation of a research project that aims at writing the history of computing in Sweden in the mainframe age from a user perspective. Rather than beginning with the history of hardware, this project takes as its point of departure the way in which actors in different sectors of society used computer technology in order to achieve a higher degree of control over crucial processes, whether through electronic data processing systems, process control or technical/scientific computation.
  • Svedberg, U.R.A., et al. (författare)
  • Emission of hexanal and carbon monoxide from storage of wood pellets, a potential occupational and domestic health hazard
  • 2004
  • Ingår i: Annals of Occupational Hygiene. - 0003-4878. ; 48:4, s. 339-349
  • Tidskriftsartikel (refereegranskat)abstract
    •  Objectives: The objective of the present study was to investigate and describe the emissions of volatile compounds, particularly hexanal and carbon monoxide, from large- and small-scale storage of wood pellets.Methods: Air sampling was performed with Fourier transform infrared spectroscopy and adsorbent sampling in pellet warehouses, domestic storage rooms, lumber kiln dryers and experimental set-ups. Literature studies were included to describe the formation of hexanal and carbon monoxide and the toxicology of hexanal.Results: A geometric mean aldehyde level of 111 +/- 32 mg/m(3) was found in one warehouse, with a peak reading of 156 mg/m(3). A maximum aldehyde reading of 457 mg/m(3) was recorded at the surface of a pellet pile. Hexanal (70-80% w/w) and pentanal (10-15% w/w) dominated, but acetone (821 +/- 24 mg/m(3)), methanol (18 7 mg/m(3)) and carbon monoxide (56 +/- 4 mg/m(3)) were also found. The emissions in a domestic storage room varied with the ambient temperature and peaked after 2 months storage in the midst of the warm season. Aldehyde levels of 98 +/- 4 mg/m(3) and carbon monoxide levels of 123 +/- 10 mg/m(3) were recorded inside such storage rooms. Elevated levels of hexanal (0.084 mg/m(3)) were recorded inside domestic housing and 6 mg/m(3) in a room adjacent to a poorly sealed storage area. Experimental laboratory studies confirmed the findings of the field studies. A field study of the emissions from industrial lumber drying also showed the formation of aldehydes and carbon monoxide.Conclusions: High levels of hexanal and carbon monoxide were strongly associated with storage of wood pellets and may constitute an occupational and domestic health hazard. The results from lumber drying show that the emissions of hexanal and carbon monoxide are not limited to wood pellets but are caused by general degradation processes of wood, facilitated by drying at elevated temperature. Emission of carbon monoxide from wood materials at low temperatures (<100degreesC) has not previously been reported in the literature. We postulate that carbon monoxide is formed due to autoxidative degradation of fats and fatty acids. A toxicological literature survey showed that the available scientific information on hexanal is insufficient to determine the potential risks to health. However, the data presented in this paper seem sufficient to undertake preventive measures to reduce exposure to hexanal.
  • Pecorari, Diane, et al. (författare)
  • English textbooks in parallel-language tertiary education
  • 2011
  • Ingår i: TESOL Quarterly. - 0039-8322. ; 45:2, s. 313-333
  • Tidskriftsartikel (refereegranskat)abstract
    • Tertiary education in many countries is increasingly bilingual, with English used in parallel with the national language, particularly as a reading language. This article describes the results of a survey of student attitudes toward, and reading practices regarding, English language textbooks. Over 1,000 students at three Swedish universities responded to a questionnaire asking about their experiences with English textbooks. Textbooks written in English were generally unpopular, and the perception was widespread that they placed a greater burden on students. However, respondents were divided about whether their reading behavior and their learning outcomes were affected by having a textbook in English, and about whether English texts were desirable. The findings of this study have implications for teaching practices in contexts in which students are asked to read, or are being prepared to read, in a second language. Implications for the English as a foreign language or English as a second language classroom are discussed.
  • Anund, Anna, et al. (författare)
  • The effects of driving situation on sleepiness indicators after sleep loss : A driving simulator study
  • 2009
  • Ingår i: Industrial Health. - 0019-8366. ; 47:4, s. 393-401
  • Tidskriftsartikel (refereegranskat)abstract
    • Almost all studies of sleepy driving are carried out in driving simulators and with monotonous road conditions (no interaction with other cars). The present study investigated indicators of sleepy driving in a more challenging scenario after a night awake. 17 participants drove a high fidelity moving base driving simulator experiment while sleepiness was monitored physiologically and behaviourally. Short periods of situations of free driving (no other vehicles) alternated with short periods of following another vehicle (car following) with and without the possibility to overtake. The result showed that a night of prior sleep loss increased sleepiness levels at the wheel (eye closure duration and lateral variability) compared to after a night of normal sleep. Blink duration while overtaking was significantly lower compared to the other situations, it was at the same level as after night sleep. Speed when passing a stopped school bus was not significantly affected by sleepiness. However the warning caused a more rapid reduction of speed. In conclusion, a moderately challenging driving contest did not affect sleepiness indicators, but a very challenging one did so (overtaking). This suggests that it is important to monitor the driving situation in field operational tests of sleepy driving.
  • Hallvig, David, et al. (författare)
  • Sleepy driving on the real road and in the simulator - A comparison
  • 2013
  • Ingår i: Accident Analysis and Prevention. - 0001-4575. ; 50, s. 44-50
  • Tidskriftsartikel (refereegranskat)abstract
    • Sleepiness has been identified as one of the most important factors contributing to road crashes. However, almost all work on the detailed changes in behavior and physiology leading up to sleep related crashes has been carried out in driving simulators. It is not clear, however, to what extent simulator results can be generalized to real driving. This study compared real driving with driving in a high fidelity, moving base, driving simulator with respect to driving performance, sleep related physiology (using electroencephalography and electrooculography) and subjective sleepiness during night and day driving for 10 participants. The real road was emulated in the simulator. The results show that the simulator was associated with higher levels of subjective and physiological sleepiness than real driving. However, both for real and simulated driving, the response to night driving appears to be rather similar for subjective sleepiness and sleep physiology. Lateral variability was more responsive to night driving in the simulator, while real driving at night involved a movement to the left in the lane and a reduction of speed, both of which effects were absent in the simulator. It was concluded that the relative validity of simulators is acceptable for many variables, but that in absolute terms simulators cause higher sleepiness levels than real driving. Thus, generalizations from simulators to real driving must be made with great caution.
  • Lindskog, C., et al. (författare)
  • The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling
  • 2015
  • Ingår i: BMC Genomics. - 1471-2164. ; 16
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: To understand cardiac and skeletal muscle function, it is important to define and explore their molecular constituents and also to identify similarities and differences in the gene expression in these two different striated muscle tissues. Here, we have investigated the genes and proteins with elevated expression in cardiac and skeletal muscle in relation to all other major human tissues and organs using a global transcriptomics analysis complemented with antibody-based profiling to localize the corresponding proteins on a single cell level. Results: Our study identified a comprehensive list of genes expressed in cardiac and skeletal muscle. The genes with elevated expression were further stratified according to their global expression pattern across the human body as well as their precise localization in the muscle tissues. The functions of the proteins encoded by the elevated genes are well in line with the physiological functions of cardiac and skeletal muscle, such as contraction, ion transport, regulation of membrane potential and actomyosin structure organization. A large fraction of the transcripts in both cardiac and skeletal muscle correspond to mitochondrial proteins involved in energy metabolism, which demonstrates the extreme specialization of these muscle tissues to provide energy for contraction. Conclusions: Our results provide a comprehensive list of genes and proteins elevated in striated muscles. A number of proteins not previously characterized in cardiac and skeletal muscle were identified and localized to specific cellular subcompartments. These proteins represent an interesting starting point for further functional analysis of their role in muscle biology and disease.
  • Perman, Jeanna, 1981-, et al. (författare)
  • The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction.
  • 2011
  • Ingår i: The Journal of clinical investigation. - 1558-8238. ; 121:7, s. 2625-40
  • Tidskriftsartikel (refereegranskat)abstract
    • Reduced oxygen availability promotes triglyceride accumulation in hearts (1) and cardiomyocytes (2). Although it is well established that lipid accumulation in hypoxic conditions can be at least partly explained by a metabolic shift from oxidation of glucose and fatty acids to glycolysis (3, 4), it is not clear whether these metabolic changes alone are sufficient or if there is also a requirement for increased uptake of lipids. Potential mechanisms for lipid uptake include receptor-mediated endocytosis of lipoproteins, lipoprotein lipase–catalyzed (LPL-catalyzed) hydrolysis of triglycerides (5), and protein-facilitated uptake of fatty acids (reviewed in ref. 6). Accumulation of triglycerides in the myocardium is associated with impaired cardiac function (7–10), but it is not known whether there is a causative link between these 2 phenomena. Intracellular triglycerides, which are stored in the hydrophobic core of lipid droplets and surrounded by amphipathic lipids and proteins (reviewed in ref. 11), are most likely very inert and thus not directly lipotoxic (12). However, it is possible that products formed during the degradation of triglycerides, such as diglycerides and fatty acids, and ceramides, which are formed from fatty acids, may have a pronounced effect on myocardial function and survival. Hypoxia/ischemia is also known to promote ER stress or the unfolded protein response. This response involves the production of chaperones to promote the folding process and maintain ER homeostasis, but unresolved ER stress leads to apoptotic cell death (reviewed in refs. 13, 14). Recent evidence suggests that ER stress plays an important role in the progression of cardiovascular diseases including ischemic heart disease, indicating that strategies to reduce ER stress may be beneficial in the ischemic heart (15). The aims of this investigation were to clarify the mechanisms behind the accumulation of lipids in the myocardium during ischemia and to determine the effect of lipid accumulation on survival following an acute myocardial infarction. We show that hypoxia/ischemia increased expression of the VLDL receptor (VLDLR) in HL-1 cardiomyocytes and mouse hearts, and that expression of the VLDLR was essential for lipid accumulation during hypoxia/ischemia. Furthermore, VLDLR mRNA expression was higher in ischemic versus nonischemic human hearts. Importantly, survival was increased and infarct size, ER stress, and apoptosis were reduced in Vldlr–/– compared with Vldlr+/+ mice following an induced myocardial infarction. We also demonstrated that blockade of the VLDLR with antibodies reduced ischemia-induced lipid accumulation, ER stress, and apoptosis in mouse heart tissue. We therefore propose that the VLDLR-induced lipid accumulation in the ischemic heart worsens survival by increasing ER stress and apoptosis.
  • van Leeuwen, Wessel M A, et al. (författare)
  • Sleep, Sleepiness, and Neurobehavioral Performance While on Watch in a Simulated 4 Hours on/8 Hours off Maritime Watch System
  • 2013
  • Ingår i: Chronobiology International. - 0742-0528. ; 30:9, s. 1108-1115
  • Tidskriftsartikel (refereegranskat)abstract
    • Seafarer sleepiness jeopardizes safety at sea and has been documented as a direct or contributing factor in many maritime accidents. This study investigates sleep, sleepiness, and neurobehavioral performance in a simulated 4?h on/8?h off watch system as well as the effects of a single free watch disturbance, simulating a condition of overtime work, resulting in 16?h of work in a row and a missed sleep opportunity. Thirty bridge officers (age 30?±?6 yrs; 29 men) participated in bridge simulator trials on an identical 1-wk voyage in the North Sea and English Channel. The three watch teams started respectively with the 00-04, the 04-08, and the 08-12 watches. Participants rated their sleepiness every hour (Karolinska Sleepiness Scale [KSS]) and carried out a 5-min psychomotor vigilance test (PVT) test at the start and end of every watch. Polysomnography (PSG) was recorded during 6 watches in the first and the second half of the week. KSS was higher during the first (mean?±?SD: 4.0?±?0.2) compared with the second (3.3?±?0.2) watch of the day (p?<?0.001). In addition, it increased with hours on watch (p?<?0.001), peaking at the end of watch (4.1?±?0.2). The free watch disturbance increased KSS profoundly (p?<?0.001): from 4.2?±?0.2 to 6.5?±?0.3. PVT reaction times were slower during the first (290?±?6?ms) compared with the second (280?±?6?ms) watch of the day (p?<?0.001) as well as at the end of the watch (289?±?6?ms) compared with the start (281?±?6?ms; p?=?0.001). The free watch disturbance increased reaction times (p?<?0.001) from 283?±?5 to 306?±?7?ms. Similar effects were observed for PVT lapses. One third of all participants slept during at least one of the PSG watches. Sleep on watch was most abundant in the team working 00-04 and it increased following the free watch disturbance. This study reveals that-within a 4?h on/8?h off shift system-subjective and objective sleepiness peak during the night and early morning watches, coinciding with a time frame in which relatively many maritime accidents occur. In addition, we showed that overtime work strongly increases sleepiness. Finally, a striking amount of participants fell asleep while on duty.
Skapa referenser, mejla, bekava och länka
fritt online (8563)
Typ av publikation
tidskriftsartikel (22016)
konferensbidrag (17471)
doktorsavhandling (3567)
licentiatavhandling (3323)
rapport (2752)
bokkapitel (1476)
visa fler...
bok (378)
samlingsverk (redaktörskap) (245)
patent (114)
annan publikation (51)
forskningsöversikt (9)
recension (9)
visa färre...
Typ av innehåll
refereegranskat (33568)
övrigt vetenskapligt (16347)
populärvet., debatt m.m. (1382)
Kildal, Per-Simon, 1 ... (605)
Liu, Johan, 1960-, (392)
Wiberg, Nils-Erik, 1 ... (380)
Nordén, Bengt, 1945- ... (378)
Skoglundh, Magnus, 1 ... (350)
Leckner, Bo, 1936-, (321)
visa fler...
Runesson, Kenneth, 1 ... (309)
Johnsson, Filip, 196 ... (305)
Lennartson, Bengt, 1 ... (293)
Berntsson, Thore, 19 ... (293)
Karlsson, Magnus, 19 ... (292)
Skarnemark, Gunnar, ... (282)
Nielsen, Jens B., 19 ... (280)
Zirath, Herbert, 195 ... (276)
Andrekson, Peter, 19 ... (262)
Larsson, Anders, 195 ... (253)
Stake, Jan, 1971-, (250)
Kasemo, Bengt, 1942- ... (247)
Lyngfelt, Anders, 19 ... (242)
Caldenby, Claes, 194 ... (242)
Gubanski, Stanislaw, ... (241)
Petersson, Göran, 19 ... (241)
Gevorgian, Spartak, ... (240)
Svensson, Arne, 1955 ... (232)
Enoksson, Peter, 195 ... (224)
Ekberg, Christian, 1 ... (223)
Olsson, Lisbeth, 196 ... (216)
Löfdahl, Lennart, 19 ... (211)
Davidson, Lars, 1957 ... (209)
Söderberg, Rikard, 1 ... (208)
Fahlén, Per, 1947-, (207)
Bohlin, Erik, 1961-, (205)
Wang, Shumin, 1963-, (202)
Persson, Mikael, 195 ... (198)
Zhdanov, Vladimir P. ... (198)
Eriksson, Thomas, 19 ... (190)
Agrell, Erik, 1965-, (190)
Tsigas, Philippas, 1 ... (190)
Nilsson, Thomas, 196 ... (186)
Svensson, Tommy, 197 ... (184)
Karlsson, MariAnne, ... (183)
Gadde, Lars-Erik, 19 ... (176)
Molander, Sverker, 1 ... (173)
Jonson, Björn, 1941- ... (172)
Mattisson, Tobias, 1 ... (171)
Gu, Irene Y.H., 1953 ... (171)
Larsson, Ragnar, 196 ... (168)
Tepfers, Ralejs, 193 ... (167)
Ström, Erik G., 1965 ... (166)
Larsson, Fredrik, 19 ... (166)
visa färre...
Göteborgs universitet (4969)
Kungliga Tekniska Högskolan (713)
Lunds universitet (581)
Linköpings universitet (469)
Uppsala universitet (361)
visa fler...
Högskolan i Jönköping (257)
Högskolan i Borås (252)
Stockholms universitet (242)
Luleå tekniska universitet (199)
Karolinska Institutet (183)
Umeå universitet (150)
Högskolan i Halmstad (130)
Högskolan Väst (110)
Sveriges Lantbruksuniversitet (107)
Mälardalens högskola (86)
Linnéuniversitetet (84)
Karlstads universitet (77)
Högskolan i Skövde (67)
VTI - Statens väg- och transportforskningsinstitut (56)
Blekinge Tekniska Högskola (49)
Mittuniversitetet (46)
Örebro universitet (44)
Högskolan Dalarna (42)
Malmö högskola (39)
Södertörns högskola (29)
Försvarshögskolan (11)
Högskolan i Gävle (11)
Högskolan Kristianstad (5)
Ersta Sköndal högskola (3)
Konstfack (2)
Röda Korsets Högskola (1)
Handelshögskolan i Stockholm (1)
Naturvårdsverket (1)
visa färre...
Engelska (48409)
Svenska (2803)
Tyska (77)
Franska (17)
Ryska (12)
Danska (11)
visa fler...
Spanska (8)
Norska (6)
Italienska (4)
Finska (4)
Japanska (1)
visa färre...
Ämne (HSV)
Teknik (31591)
Naturvetenskap (21240)
Samhällsvetenskap (3241)
Medicin och hälsovetenskap (1618)
Humaniora (960)
Lantbruksvetenskap (507)


pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy