| 1. |
|
|
| 2. |
- Vasilopoulos, T, et al.
(författare)
-
Genetic Covaration of Grip Strength and General Cognitive Ability in Octogenarian Swedish Twins
- 2007
-
Ingår i: At the 60th Annual Scientific Meeting “The Era of Global Aging: Challenges and Opportunities”. The Gerontologist, vol 47, Spical issue II, Oct. 2007.. ; , s. 465-
-
Konferensbidrag (refereegranskat)abstract
- Grip strength is a strong predictor of later-life disability, morbidity and mortality. Likewise, reduced grip strength has been associated with cognitive decline. Using quantitative genetic techniques, we surveyed the contribution of genetic and environmental factors to the relationship between grip strength and general cognitive ability in 100 monozygotic and 131 dizygotic twin pairs. The sample was selected from the longitudinal study, “Origins of Variance in the Old-Old.” For the analysis, a latent general cognitive ability factor was constructed using measures of verbal ability, spatial ability, speed of processing, and memory. Bivariate model fitting revealed that genetic factors accounted for 74% of the phenotypic correlation ( r = .47) between grip strength and general cognitive ability. These results suggest that shared genetic factors underlie the relationship between grip strength and general cognitive ability and may also support the theory that common factors contribute to overall age-related deterioration of cognitive and non-cognitive functioning. Supported by grants from the National Institute on Aging at the National Institutes of Health (AG08861 and AG000276)
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
- Berg, Anne Ingeborg, 1973, et al.
(författare)
-
Behavioral & Social Sciences : If I only had a good health”: A study of relationships between life satisfaction and medical diagnoses in the oldest-old.
- 2007
-
Ingår i: At the 60th Annual Scientific Meeting “The Era of Global Aging: Challenges and Opportunities” The Gerontologist, vol 47, Spical issue II, Oct. 2007.
-
Konferensbidrag (refereegranskat)abstract
- People often claim that health makes the difference for life-satisfaction and well-being in late life. It is, however, typically found that self-report is the health measure that makes a difference in these outcomes, rather than medically based measures. Noteworthy, few studies have so far included a comprehensive set of common diagnoses based on medical records. The present study investigated the relationship between life satisfaction and medical diagnoses among 412 non-demented individuals drawn from the Swedish OCTO-Twin study. Analysis of covariance showed that when gender and age were controlled for, only 6 out of 50 diagnoses were related to lower life satisfaction. These were (prevalence in parenthesis) sleeping problems (65%), dizziness (64%), rheumatoid arthritis (3%), stroke (20%), and urine incontinence (51%). The study provides support for a relationship in diseases that affect everyday life functioning among a substantial proportion of the oldest old. Benefits and Learning Objectives • The relationship between life satisfaction and a range of common medical diagnoses in the oldest-old.
|
|
| 6. |
- Berg, Anne Ingeborg, 1973, et al.
(författare)
-
Importance of functional capacity for life-satisfaction in late life: Findings in a population-based sample aged 80 and older
- 2004
-
Ingår i: Presented at 17th Nordic Congress in Gerontology (Stockholm, Sweden).
-
Konferensbidrag (refereegranskat)abstract
- Aging is accompanied with numerous biological and social changes that may compromise life-satisfaction. Aim: To examine the relative impact on life-satisfaction from functional limitations within the context of social, cognitive, and health related factors in the oldest-old. Methods and Material: Scales and questions regarding life-satisfaction (LSI-Z-index), functional capacity (instrumental and personal ADL), depression (CES-D), cognitive function (MMSE), social support, and economy was administered in a sample of 504 participants, aged 80–98 years; (M=83 years, 68 % women). Results: Regression analysis indicated that functional capacity is associated with life-satisfaction but other variables such as subjective health, social support, and economy were equally important. Discussion: The results correspond with previous studies and emphasize the need to analyze the relationship between functional limitations and disability within a broader context of social, emotional, and cognitive variables
|
|
| 7. |
|
|
| 8. |
- Berg, Anne Ingeborg, 1973, et al.
(författare)
-
Satisfaction With Past, Present and Future life: The Role of Personality and Locus of Control
- 2016
-
Ingår i: 2016 Annual Meeting Gerontological Society of America.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Eriksson proposed that being satisfied with the way life turned out is a central developmental task of old age, leading to as sense of integrity that also will bring satisfaction to present life. However, life satisfaction has so far commonly been studied as a global measure disregarding the temporal domains of satisfaction with life. The three-factor solution of the LSI-Z (Neugarten, 1961); Congruence (past-oriented), Mood (present-oriented) and Zest (future-oriented), enables the investigation of different trajectories and factors of relevance for different temporal domains of life satisfaction. The present study investigates the unique associations between level and change in the LSI-Z factors Congruence, Mood, and Zest, and their associations to personality and locus of control across four measurement occasions over six years in a sample of 80-98 year old individuals from the OCTO-Twin-study. MLM growth curve analyses showed that Mood and Zest decreased over time, but Congruence remained stable. Extraversion was related to level of Congruence and Zest, but not to Mood. Neuroticism was related to Mood and Zest but not to Congruence. Locus of control was not related to Congruence, but to Mood and Zest. The results indicate that individual perceptions of quality of life in past, present and future life is related to personality and sense of control. Different associations between personality and control and temporal dimension of the life satisfaction concept have implications for research on quality of life in older adults.
|
|
| 9. |
|
|
| 10. |
- Cadar, Dorina, et al.
(författare)
-
Does education explain the terminal decline in the oldest-old? Evidence from two longitudinal studies of ageing
- 2015
-
Ingår i: The Lancet. - 0140-6736. ; 386:Supplement 2
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- AbstractBackground Cognitive performance substantially deteriorates close to death, as postulated by the terminal decline hypothesis. However, the association between education and terminal decline remains controversial. This study investigated the role of education in terminal decline in two European longitudinal studies of oldest-old. Methods Participants were from the Newcastle 85+, UK (n=702), and Octogenarian Twins (OCTO-Twin), Sweden (n= 845). They were assessed biannually over three and five consecutive waves, respectively. In a coordinated analysis, multilevel models were used to examine the association between education and terminal decline on mini-mental state examination (MMSE), controlling for age at baseline, dementia incidence, sex, and time to death from the study entry within each cohort. Cognitive decline was modelled as a linear function of time to death in both cohorts and as a quadratic function in the OCTO-Twin study (because of longer follow-up). Education was a continuous measure (ranging from 6 to 20 years in Newcastle 85+ and 0 to 23 years in OCTO-Twin). Findings A typical British man, aged 85 at baseline, with 10 years’ education, entered the terminal phase at around 2·5 years before death, and the mean rate of decline was −1·04 MMSE points with each year closer to the time of death (SEM 0·25, p<0·0001). By contrast, a Swedish man, aged 83 years, with an average of 7 years’ education, entered the terminal phase at around 8 years from death, after which the rate of cognitive decline steepened by −1·70 points per year closer to the time of death (SEM 0·20, p<0·0001) and accelerated by −0·11 (SEM 0·01, p<0·0001). Education was positively associated with the estimated mean MMSE scores before death only in OCTO-Twin (0·43, SEM 0·15; p=0·003) and did not attenuate the rate of terminal decline in either cohort. Interpretation Decline and acceleration of this decline were detectable in both studies before death, with steeper rates of decline observed in the Swedish cohort. However, this process was not lessened by education itself. This work contributes to a better understanding of the transition from the subtle cognitive changes associated with age to those of neurological substance, and the role of education in this decline. Funding The funding sources of this work were the Alzheimer's Society (grant number 144) and the Medical Research Council (unit programme number MC_UU_12019/1).
|
|
