Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "swepub ;srt2:(2007)"

Sökning: swepub > (2007)

  • Resultat 1-10 av 57621
Sortera/gruppera träfflistan
  • Adolfsson, Jan, et al. (författare)
  • Clinical characteristics and primary treatment of prostate cancer in Sweden between 1996 and 2005 - Data from the national prostate cancer register in Sweden
  • 2007
  • Ingår i: Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00. - Taylor & Francis. - 0036-5599. ; 41:6, s. 456-477
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective. The incidence of prostate cancer is rising rapidly in Sweden and there is a need to better understand the pattern of diagnosis, tumor characteristics and treatment. Material and methods. Between 1996 and 2005, all new cases of adenocarcinoma of the prostate gland were intended to be registered in the National Prostate Cancer Register (NPCR). This register contains information on diagnosing unit, date of diagnosis, cause of diagnosis, tumor grade, tumor stage according to the TNM classification in force, serum prostate-specific antigen (PSA) levels at diagnosis and primary treatment given within the first 6 months after diagnosis. Results. In total, 72 028 patients were registered, comprising > 97% of all pertinent incident cases of prostate cancer in the Swedish Cancer Register (SCR). During the study period there was a considerable decrease in median age at the time of diagnosis, a stage migration towards smaller tumors, a decrease in median serum PSA values at diagnosis, a decrease in the age-standardized incidence rate of men diagnosed with distant metastases or with a PSA level of > 100 ng/ml at diagnosis and an increase in the proportion of tumors with Gleason score <= 6. Relatively large geographical differences in the median age at diagnosis and the age-standardized incidence of cases with category T1c tumors were observed. Treatment with curative intent increased dramatically and treatment patterns varied according to geographical region. In men with localized tumors and a PSA level of <20 ng/ml at diagnosis, expectant treatment was more commonly used in those aged >= 75 years than in those aged <75 years. Also, the pattern of endocrine treatment varied in different parts of Sweden. Conclusions. All changes in the register seen over time are consistent with increased diagnostic activity, especially PSA testing, resulting in an increased number of cases with early disease, predominantly tumors in category T1c. The patterns of diagnosis and treatment of prostate cancer vary considerably in different parts of Sweden. The NPCR continues to be an important source for research, epidemiological surveillance of the incidence, diagnosis and treatment of prostate cancer.
  • Mamhidir, Anna-Greta, et al. (författare)
  • Weight increase in patients with dementia, and alteration in meal routines and meal environment after integrity promoting care.
  • 2007
  • Ingår i: Journal of Clinical Nursing. - 0962-1067. ; 16:5, s. 987-96
  • Tidskriftsartikel (refereegranskat)abstract
    • AIMS: To follow weight changes in patients with moderate and severe dementia and analyse how these changes related to biological and psychological parameters after staff education and support in integrity promoting care. A further aim was to describe meal environment and routines relative to the intervention. BACKGROUND: Weight loss in patients with dementia and in particular Alzheimer’s disease (AD) is common. The etiology appears multifactorial with the meal environment and a decreased independence while eating among the factors. METHOD: Over a three-month intervention period, an integrity-promoting care training program was conducted with the staff of a long-term ward. AD patients, 18 from an intervention ward and 15 from a control ward were included and possible effects were evaluated. Weighing was conducted at the start and after completion of the intervention. Weight changes were analyzed in relation to psychological and biochemical parameters. In addition, the staff wrote diaries about e.g. changes made in the environment and in their work.RESULTS: The most prominent difference observed was weight increases in 13 of 18 patients compared to two of 15 patients in the control ward. No weight changes were related to the type of dementia. The individual weight changes correlated significant to changes in the intellectual functions. Relationships between weight change, increased motor function and increased appetite were non-significant. There was no significant relationship between weight changes and changes in biochemical parameters. According to the staff, increased contact with the patients and a more pleasant atmosphere resulted when the meal environment and routines were changed. RELEVANCE TO CLINICAL PRACTICE: Weight gain in patients with moderate and severe dementia was achieved by adjusting the meal environment to the individual’s needs. Staff education was profitable, as increased competence seemed to promote individually adapted feeding situations. Ensuring good meal situations need to be given high priority.
  • Augutis, M, et al. (författare)
  • Psychosocial aspects of traumatic spinal cord injury with onset during adolescence: A qualitative study
  • 2007
  • Ingår i: JOURNAL OF SPINAL CORD MEDICINE. - 1079-0268. ; 30, s. S55-S64
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND/OBJECTIVE: Spinal cord injury (SCI) occurring during adolescence poses additional challenges because of the concurrent age-specific bio-psychosocial development. Full understanding of the psychosocial dimensions of rehabilitation requires exploration of the patient perspective. The objective of this study was to focus on psychosocial factors from the patient perspective in persons who had previously sustained a SCI during early and mid-adolescence (11-15 years of age). METHODS: Twenty-four of the 28 persons who had sustained a SCI in Sweden from 1985 to 1996 participated in the study. Semistructured interviews were made an average of 10 years after injury. Narratives were analyzed qualitatively according to content analysis. RESULTS: Parents and peers were found to have formed a crucial network. Parents frequently acted as advocates in interactions with health care providers, as supporters, and as containers of sorrow, frustration, and anger. Peers acted as promoters of activity and identity development. However, health care providers were perceived as not making sufficient use of this network. CONCLUSIONS: Rehabilitation professionals might be encouraged to increase their knowledge of adolescence medicine to better meet the specific needs and demands of persons in this age group. It is further suggested that parents and peers be considered important partners in the joint rehabilitation effort.
  • Askling, Johan, et al. (författare)
  • Time-dependent increase in risk of hospitalisation with infection among Swedish RA patients treated with TNF antagonists
  • 2007
  • Ingår i: Annals of the Rheumatic Diseases. - British Medical Association. - 1468-2060. ; 66:10, s. 1339-1344
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives: The degree to which treatment with tumour necrosis factor (TNF) antagonists may be associated with increased risks for serious infections is unclear. An observational cohort study was performed using prospectively collected data from the Swedish Biologics Register (ARTIS) and other national Swedish registers. Methods: First, in the ARTIS, all 4167 rheumatoid arthritis ( RA) patients starting TNF antagonist treatment between 1999 and 2003 were identified. Secondly, in the Swedish Inpatient Register, all individuals hospitalised for any reason and who also carried a diagnosis of RA, between 1964 and 2003 (n = 44 946 of whom 2692 also occurred in ARTIS), were identified. Thirdly, in the Swedish Inpatient Register, all hospitalisations listing an infection between 1999 and 2003 were identified. By cross-referencing these three data sets, RRs for hospitalisation with infection associated with TNF antagonist treatment were calculated within the cohort of 44 946 RA patients, using Cox regression taking sex, age, geography, co-morbidity and use of inpatient care into account. Results: Among the 4167 patients treated with TNF antagonists, 367 hospitalisations with infections occurred during 7776 person-years. Within the cohort of 44 496 RA patients, the RR for infection associated with TNF antagonists was 1.43 ( 95% CI 1.18 to 1.73) during the first year of treatment, 1.15 ( 95% CI 0.88 to 1.51) during the second year of treatment, and 0.82 ( 95% CI 0.62 to 1.08) for subjects remaining on their first TNF antagonist treatment after 2 years. Conclusion: Treatment with TNF antagonists may be associated with a small to moderate increase in risk of hospitalisation with infection, which disappears with increasing treatment duration.
  • Waldenström, Jonas, et al. (författare)
  • Migrating birds and tickborne encephalitis virus
  • 2007
  • Ingår i: Emerging Infectious Diseases. - 1080-6040. ; 13:8, s. 1215-8
  • Tidskriftsartikel (refereegranskat)abstract
    • During spring and autumn 2001, we screened 13,260 migrating birds at Ottenby Bird Observatory, Sweden, and found 3.4% were infested with ticks. Four birds, each a different passerine species, carried tickborne encephalitis virus (TBEV)-infected ticks (Ixodes ricinus). Migrating birds may play a role in the geographic dispersal of TBEV-infected ticks.
  • Wallensten, Anders, et al. (författare)
  • Surveillance of influenza A virus in migratory waterfowl in northern Europe
  • 2007
  • Ingår i: Emerging Infectious Diseases. - 1080-6040. - 1080-6040 ; 13:3, s. 404-411
  • Tidskriftsartikel (refereegranskat)abstract
    • We conducted large-scale, systematic sampling of influenza type A virus in migratory waterfowl (mostly mallards [Anas platyrhynchos]) at Ottenby Bird Observatory, southeast Sweden. As with previous studies, we found a higher prevalence in fall than spring, and among juveniles compared with adults. However, in contrast to other studies, we found that prevalence in spring was sometimes high (mean 4.0%, highest 9.5%). This finding raises the possibility that ducks are capable of perpetuating influenza A virus of different subtypes and subtype combinations throughout the year and from 1 year to the next. Isolation of the H5 and H7 subtypes was common, which suggests risk for transmission to sensitive domestic animals such as poultry. We argue that wild bird screening can function as a sentinel system, and we give an example of how it could have been used to forecast a remote and deadly outbreak of influenza A in poultry.
  • Wallin, Åsa K., et al. (författare)
  • Donepezil in Alzheimer's disease : What to expect after 3 years of treatment in a routine clinical setting
  • 2007
  • Ingår i: Dementia and Geriatric Cognitive Disorders. - 1420-8008. ; 23:3, s. 150-160
  • Tidskriftsartikel (refereegranskat)abstract
    • Background/Aims: Clinical short-term trails have shown positive effects of donepezil treatment in patients with Alzheimer's disease. The outcome of continuous long-term treatment in the routine clinical settings remains to be investigated. Methods: The Swedish Alzheimer Treatment Study (SATS) is a descriptive, prospective, longitudinal, multicentre study. Four hundred and thirty-five outpatients with the clinical diagnosis of Alzheimer's disease, received treatment with donepezil. Patients were assessed with Mini-Mental State Examination (MMSE), Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog), global rating (CIBIC) and Instrumental Activities of Daily Living (IADL) at baseline and every 6 months for a total period of 3 years. Results: The mean MMSE change from baseline was positive for more than 6 months and in subgroups of patients for 12 months. After 3 years of treatment the mean change from baseline in MMSE-score was 3.8 points (95% CI, 3.0-4.7) and the ADAS-cog rise was 8.2 points (95% CI, 6.4-10.1). This is better than expected in untreated historical cohorts, and better than the ADAS-cog rise calculated by the Stern equation (15.6 points, 95% CI, 14.5-16.6). After 3 years with 38% of the patients remaining, 30% of the them were unchanged or improved in the global assessment. Conclusion: Three-year donepezil treatment showed a positive global and cognitive outcome in the routine clinical setting. Copyright © 2007 S. Karger AG.
  • Axelsson, Ann-Sofie, et al. (författare)
  • Att etablera ett kollaboratorium inom biblioteks- och informationsvetenskap: behov och utmaningar från ett praktikerperspektiv
  • 2007
  • Ingår i: Svensk Biblioteksforskning. - 0284-4354. ; 16:1
  • Tidskriftsartikel (refereegranskat)abstract
    • This article describes a study that investigated the need for and challenges connected to the establishment of a collaboratory - a sociotechnical forum where information and other resources can be made accessible and used by practitioners within library and information science. In order to identify needs and challenges interviews were carried out with a number of practitioners at a number of different institutions. The results reveal that there is a need for a collaboratory in order to facilitate the sharing of personal knowledge “on demand”. It is of great importance that the collaboratory is well integrated with practitioner’s daily activities.
  • Påhlman, Lars, et al. (författare)
  • The Swedish rectal cancer registry.
  • 2007
  • Ingår i: The British journal of surgery. - 1365-2168. ; 94:10, s. 1285-92
  • Tidskriftsartikel (refereegranskat)abstract
    • Background:An audit of all patients with rectal cancer in Sweden was launched in 1995. This is the first report from the Swedish Rectal Cancer Registry (SRCR).Methods:Between 1995 and 2003, 13 434 patients treated for adenocarcinoma of the rectum were registered with the SRCR; there were approximately 1500 new patients annually.Results:Approximately half had an anterior resection, a quarter an abdominoperineal resection and 15 per cent a Hartmann's procedure. The median 30-day postoperative mortality rate was 2·4 per cent and the overall postoperative morbidity rate was 35·0 per cent. The 5-year cancer-specific survival rate was 62·3 per cent. The 5-year relative survival rate was 70·1 per cent after anterior resection, 59·8 per cent after abdominoperineal resection and 39·8 per cent after a Hartmann's procedure. The crude 5-year local recurrence rate was 9·5 per cent overall, 6·1 per cent after preoperative radiotherapy and 11·4 per cent after surgery alone. For 3868 patients who had a locally curative procedure the local recurrence rate was 7·4 per cent overall, 5·9 per cent for those who had radiotherapy and 10·2 per cent for those who did not. The local recurrence rate was 2·9 per cent (28 of 968) for stage I disease, 7·9 per cent (112 of 1418) for stage II, 13·9 per cent (188 of 1357) for stage III and 8·5 per cent (45 of 532) for stage IV.Conclusion:These good population-based results are due, in part, to the nationwide prospective quality assurance registration.
  • Sedimbi, S K, et al. (författare)
  • SUMO4 M55V polymorphism affects susceptibility to type I diabetes in HLA DR3- and DR4-positive Swedish patients
  • 2007
  • Ingår i: Genes Immun. - 1466-4879 (Print). ; 8:6, s. 518-21
  • Tidskriftsartikel (refereegranskat)abstract
    • SUMO4 M55V, located in IDDM5, has been a focus for debate because of its association to type I diabetes (TIDM) in Asians but not in Caucasians. The current study aims to test the significance of M55V association to TIDM in a large cohort of Swedish Caucasians, and to test whether M55V is associated in those carrying human leukocyte antigen (HLA) class II molecules. A total of 673 TIDM patients and 535 age- and sex-matched healthy controls were included in the study. PCR–RFLP was performed to identify the genotype and allele variations. Our data suggest that SUMO4 M55V is not associated with susceptibility to TIDM by itself. When we stratified our patients and controls based on heterozygosity for HLA-DR3/DR4 and SUMO4 genotypes, we found that presence of SUMO4 GG increased further the relative risk conferred by HLA-DR3/DR4 to TIDM, whereas SUMO4 AA decreased the risk. From the current study, we conclude that SUMO4 M55V is associated with TIDM in association with high-risk HLA-DR3 and DR4, but not by itself.
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 57621
fritt online (7176)
Typ av publikation
tidskriftsartikel (27380)
konferensbidrag (13008)
bokkapitel (5709)
rapport (3508)
doktorsavhandling (2578)
recension (1212)
visa fler...
bok (1088)
annan publikation (1033)
licentiatavhandling (681)
samlingsverk (redaktörskap) (602)
forskningsöversikt (591)
proceedings (redaktörskap) (136)
patent (70)
konstnärligt arbete (42)
visa färre...
Typ av innehåll
refereegranskat (30910)
övrigt vetenskapligt (21457)
populärvet., debatt m.m. (5184)
Lundälv, Jörgen, 196 ... (91)
Sorgenfrei, Simon (62)
Harrison, Dick, (60)
He, Sailing, (58)
et. al. (54)
Johansson, Börje, (51)
visa fler...
Hemminki, K (51)
Redaktionen Fauna & ... (50)
Nilsson, Peter, (49)
Iwarsson, Susanne, (49)
Sörlin, Sverker, (48)
Berglund, Göran, (47)
Holmdahl, R, (44)
Samuelson, Lars, (44)
Laurell, Fredrik, (44)
Gustafsson, Hans-Åke ... (42)
Oskarsson, Anders, (42)
Nilsson, Fredrik, (41)
Khrennikov, Andrei, (41)
Hallin, Ann-Katrin, (41)
Larsson, Per-Olof, 1 ... (41)
Pasiskevicius, Valda ... (41)
Otterlund, Ingvar, (39)
Andersson, M (39)
Córdova, Armando, (39)
Edlund, Lars-Erik, (39)
Belanger-Champagne, ... (37)
Winblad, B (37)
Larsson, Anders, (37)
Lindholm, B, (37)
Fridlund, Bengt, (37)
Olsson, Ulf, (37)
Hansson, Sven Ove, (37)
Stenlund, Evert, (36)
Liu, Z. (36)
Stenvinkel, P, (36)
Room, Robin, (36)
Grub, Frank Thomas, ... (36)
Modéer, Kjell Å, (35)
Hansson, Per (35)
Jonsson, P. (35)
Mattiasson, Bo, (35)
Ringden, O, (35)
Gustafsson, Mats, (35)
Fuxe, K, (35)
Rodriguez, Heriberto ... (35)
Sjöberg, Birthe, (35)
Sun, Licheng (35)
Jonsson, B, (34)
visa färre...
Lunds universitet (8973)
Uppsala universitet (7379)
Göteborgs universitet (6351)
Karolinska Institutet (5478)
Stockholms universitet (4898)
Kungliga Tekniska Högskolan (4780)
visa fler...
Linköpings universitet (4045)
Sveriges Lantbruksuniversitet (3643)
Umeå universitet (3100)
Chalmers tekniska högskola (2842)
Luleå tekniska universitet (1792)
Linnéuniversitetet (1437)
Örebro universitet (1081)
Karlstads universitet (962)
Högskolan i Jönköping (894)
Mittuniversitetet (808)
Malmö högskola (729)
Södertörns högskola (721)
Mälardalens högskola (632)
RISE (568)
Högskolan i Borås (548)
Högskolan Dalarna (420)
Högskolan i Gävle (400)
Högskolan Kristianstad (400)
Högskolan i Halmstad (399)
Blekinge Tekniska Högskola (357)
Högskolan i Skövde (309)
Naturvårdsverket (252)
Högskolan Väst (171)
Ersta Sköndal Bräcke högskola (147)
VTI - Statens väg- och transportforskningsinstitut (107)
Gymnastik- och idrottshögskolan (75)
Försvarshögskolan (70)
Nordiska Afrikainstitutet (54)
Naturhistoriska riksmuseet (27)
Röda Korsets Högskola (27)
Sophiahemmet Högskola (18)
Konstfack (16)
Nationalmuseum (9)
Kungl. Musikhögskolan (2)
Stockholms konstnärliga högskola (2)
visa färre...
Engelska (44408)
Svenska (12162)
Tyska (282)
Odefinierat språk (130)
Franska (120)
Spanska (84)
visa fler...
Danska (83)
Norska (59)
Finska (42)
Italienska (38)
Ryska (32)
Kinesiska (24)
Annat språk (23)
Portugisiska (22)
Polska (21)
Nederländska (11)
Isländska (8)
Turkiska (7)
Japanska (6)
Arabiska (5)
Estniska (5)
Ungerska (5)
Litauiska (4)
Ukrainska (4)
Tjeckiska (3)
Rumänska (3)
Bulgariska (3)
Persiska (3)
Nygrekiska (2)
Nynorsk (2)
Latin (1)
Grekiska, klassisk (1)
Lettiska (1)
Slovenska (1)
Slovakiska (1)
Koreanska (1)
Esperanto (1)
Vitryska (1)
Samiska (1)
Bokmål (1)
Bosniska (1)
Iriska (1)
visa färre...
Forskningsämne (UKÄ/SCB)
Naturvetenskap (11302)
Samhällsvetenskap (11077)
Medicin och hälsovetenskap (8801)
Teknik (7639)
Humaniora (5837)
Lantbruksvetenskap (3290)
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy