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1.
  • Abdo, A. A., et al. (författare)
  • DETECTION OF GAMMA-RAY EMISSION FROM THE STARBURST GALAXIES M82 AND NGC 253 WITH THE LARGE AREA TELESCOPE ON FERMI
  • 2010
  • Ingår i: The Astrophysical Journal Letters. - 2041-8205 .- 2041-8213. ; 709:2, s. l152-L157
  • Tidskriftsartikel (refereegranskat)abstract
    • We report the detection of high-energy gamma-ray emission from two starburst galaxies using data obtained with the Large Area Telescope on board the Fermi Gamma-ray Space Telescope. Steady point-like emission above 200 MeV has been detected at significance levels of 6.8 sigma and 4.8 sigma, respectively, from sources positionally coincident with locations of the starburst galaxies M82 and NGC 253. The total fluxes of the sources are consistent with gamma-ray emission originating from the interaction of cosmic rays with local interstellar gas and radiation fields and constitute evidence for a link between massive star formation and gamma-ray emission in star-forming galaxies.
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2.
  • Abdo, A. A., et al. (författare)
  • SPECTRAL PROPERTIES OF BRIGHT FERMI-DETECTED BLAZARS IN THE GAMMA-RAY BAND
  • 2010
  • Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 710:2, s. 1271-1285
  • Tidskriftsartikel (refereegranskat)abstract
    • The gamma-ray energy spectra of bright blazars of the LAT Bright AGN Sample LBAS) are investigated using Fermi-LAT data. Spectral properties hardness, curvature, and variability) established using a data set accumulated over 6 months of operation are presented and discussed for different blazar classes and subclasses: flat spectrum radio quasars (FSRQs), low-synchrotron peaked BLLacs (LSP-BLLacs), intermediate-synchrotron peaked BLLacs (ISP-BLLacs), and high-synchrotron peaked BLLacs (HSP-BLLacs). The distribution of photon index G, obtained from a power-law fit above 100 MeV) is found to correlate strongly with blazar subclass. The change in spectral index from that averaged over the 6 months observing period is < 0.2-0.3 when the flux varies by about an order of magnitude, with a tendency toward harder spectra when the flux is brighter for FSRQs and LSP-BLLacs. A strong departure from a single power-law spectrum appears to be a common feature for FSRQs. This feature is also present for some high-luminosity LSP-BLLacs, and a small number of ISP-BLLacs. It is absent in all LBAS HSP-BLLacs. For 3C 454.3 and AO 0235+164, the two brightest FSRQ source and LSP-BLLac source, respectively, a broken power law (BPL) gives the most acceptable of power law, BPL, and curved forms. The consequences of these findings are discussed.
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3.
  • Abdo, A. A., et al. (författare)
  • THE FIRST FERMI MULTIFREQUENCY CAMPAIGN ON BL LACERTAE : CHARACTERIZING THE LOW-ACTIVITY STATE OF THE EPONYMOUS BLAZAR
  • 2011
  • Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 730:2, s. 101-
  • Tidskriftsartikel (refereegranskat)abstract
    • We report on observations of BL Lacertae during the first 18 months of Fermi LAT science operations and present results from a 48 day multifrequency coordinated campaign from 2008 August 19 to 2008 October 7. The radio to gamma-ray behavior of BL Lac is unveiled during a low-activity state thanks to the coordinated observations of radio-band (Metsahovi and VLBA), near-IR/optical (Tuorla, Steward, OAGH, and MDM), and X-ray (RXTE and Swift) observatories. No variability was resolved in gamma rays during the campaign, and the brightness level was 15 times lower than the level of the 1997 EGRET outburst. Moderate and uncorrelated variability has been detected in UV and X-rays. The X-ray spectrum is found to be concave, indicating the transition region between the low- and high-energy components of the spectral energy distribution (SED). VLBA observation detected a synchrotron spectrum self-absorption turnover in the innermost part of the radio jet appearing to be elongated and inhomogeneous, and constrained the average magnetic field there to be less than 3 G. Over the following months, BL Lac appeared variable in gamma rays, showing flares (in 2009 April and 2010 January). There is no evidence for the correlation of gamma rays with the optical flux monitored from the ground in 18 months. The SED may be described by a single-zone or a two-zone synchrotron self-Compton (SSC) model, but a hybrid SSC plus external radiation Compton model seems to be preferred based on the observed variability and the fact that it provides a fit closest to equipartition.
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4.
  • Aricescu, A R, et al. (författare)
  • Eukaryotic expression: developments for structural proteomics.
  • 2006
  • Ingår i: Acta Crystallographica Section D: Biological Crystallography. - 1399-0047 .- 0907-4449. ; 62, s. 1114-1124
  • Tidskriftsartikel (refereegranskat)abstract
    • The production of sufficient quantities of protein is an essential prelude to a structure determination, but for many viral and human proteins this cannot be achieved using prokaryotic expression systems. Groups in the Structural Proteomics In Europe (SPINE) consortium have developed and implemented high-throughput (HTP) methodologies for cloning, expression screening and protein production in eukaryotic systems. Studies focused on three systems: yeast (Pichia pastoris and Saccharomyces cerevisiae), baculovirus-infected insect cells and transient expression in mammalian cells. Suitable vectors for HTP cloning are described and results from their use in expression screening and protein-production pipelines are reported. Strategies for co-expression, selenomethionine labelling (in all three eukaryotic systems) and control of glycosylation (for secreted proteins in mammalian cells) are assessed.
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6.
  • Boyd, Philip, et al. (författare)
  • Handbook to support the SCOR Best Practice Guide for ‘Multiple Drivers’ Marine Research
  • 2019
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Marine species and ecosystems are exposed to a wide range of environmental change – both detrimental (threats) and beneficial – due to human activities. Some of the changes are global, whereas others are regional or local. It is important to distinguish the scale of each threat as the solutions will differ. For example, the mitigation of a global problem requires a global response, which is more difficult to achieve than addressing a local problem with a local response. These wide-ranging changes are often referred to drivers or stressors.
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7.
  • Hofsten, von, Claes, et al. (författare)
  • Improved visual perception in very low birth weight infants on enhanced nutrient supply
  • 2015
  • Ingår i: Neonatalogy. - : S. Karger. - 1661-7800. ; 108, s. 30-37
  • Tidskriftsartikel (refereegranskat)abstract
    • <b><i>Background:</i></b> Optimal nutrient supply to very low birth weight (VLBW: BW <1,500 g) infants is important for growth and neurodevelopment. Growth restriction is common among these infants and may be associated with neurocognitive impairments. <b><i>Objectives:</i></b> To compare an enhanced nutrient supply to a routine supply given to VLBW infants and to evaluate the effects on visual perception of global form and motion measured by visual event-related potentials (VERP). <b><i>Methods:</i></b> A total of 50 VLBW infants were randomized to an intervention group that received an increased supply of energy, protein, fat, essential fatty acids, and vitamin A or a control group that received standard nutritional care. At 5 months' corrected age the infants were examined using VERP to investigate the responses to global form and motion. VERP were analysed at the first (f1) and third (f3) harmonics of the stimulus frequency. <b><i>Results:</i></b> Data from 31 subjects were eligible for analysis. The motion VERP responses for the f1 and f3 components were stronger in the area near the posterior midline region in the intervention group compared to the controls in the group analyses (p = 0.02 and p = 0.001, respectively). <b><i>Conclusion:</i></b> The results showed a more consistent response to global motion among infants receiving enhanced nutrition. The intervention may have improved visual perception of global motion.
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8.
  • Kenward, R. E., et al. (författare)
  • Identifying governance strategies that effectively support ecosystem services, resource sustainability, and biodiversity
  • 2011
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 108:13, s. 5308-5312
  • Tidskriftsartikel (refereegranskat)abstract
    • Conservation scientists, national governments, and international conservation groups seek to devise, and implement, governance strategies that mitigate human impact on the environment. However, few studies to date have systematically investigated the performance of different systems of governance in achieving successful conservation outcomes. Here, we use a newly-developed analytic framework to conduct analyses of a suite of case studies, linking different governance strategies to standardized scores for delivering ecosystem services, achieving sustainable use of natural resources, and conserving biodiversity, at both local and international levels. Our results: (i) confirm the benefits of adaptive management; and (ii) reveal strong associations for the role of leadership. Our work provides a critical step toward implementing empirically justified governance strategies that are capable of improving the management of human-altered environments, with benefits for both biodiversity and people.
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9.
  • Lee, Sang-Han, et al. (författare)
  • Distribution of plutonium and americium in the marginal seas of the nothwest pacific ocean.
  • 2003
  • Ingår i: Deep-sea research. Part II, Topical studies in oceanography. - 0967-0645 .- 1879-0100. ; 50, s. 2727-2750
  • Tidskriftsartikel (refereegranskat)abstract
    • Plutonium isotopes and 241Am were studied in seawater and sediment from the East China Sea, the Yellow Sea, the East Sea/Sea of Japan, the Sea of Okhotsk, and the northwest Pacific Ocean, collected between 1993 and 1996 with the aim to contribute to better understanding the behaviour of plutonium and americium in the marine environment. 239,240Pu concentrations in surface water varied from 2.3 to 13 µBq l-1 in the East China Sea and from 3.5 to 9.4 µBq l-1 in the East Sea. The 239,240Pu vertical profiles in water showed a broad subsurface maximum between 500 and 1000 m with a range of 30-40 µBq l-1, and gradually decreased from 1000 m depth down to the seafloor. 241Am concentrations in surface water showed values from 1.1 to 2.2 µBq l -1 in the East Sea, from 1.0 to 3.1 µBq l-1 in the Sea of Okhotsk, and from 0.68 to 12.0 µBq l-1 in the northwest Pacific Ocean. The activity ratios of 241Am/239,240Pu in seawater showed values similar to the global fallout ratio, which suggests that the source of these radionuclides in the northwest Pacific Ocean is global fallout. However, the 241Am/239,240Pu activity ratios in sediment were found to be much higher (1.0-1.9) than the global fallout ratio (0.37), confirming that 241Am is scavenged from the water column more rapidly than 239,240Pu. The 239,240Pu inventories in the water column of the East Sea were from 0.98 to 93 Bq m-2 depending on water depth and sedimentation rates. The 241Am inventory in the water column east of Kamchatka was 6.3 ± 1.0 Bq m -2 and the sediment inventory in the Sea of Okhotsk was 16 ± 2 Bq m-2. 239,240Pu concentrations in sinking particles in the southwest Japan Basin were from 3.7 to 5.2 Bq kg-1 (dry weight) with fluxes of 0.19-4.50 mBq m-2 d-1 and at the Ulleung Basin from 2.4 to 3.7 Bq kg-1 (dry weight) with fluxes of 0.77-1.10 mBq m-2 d-1. The mean residence time of 239,240Pu in the water column of the East Sea derived from sediment trap data was 140 ± 20 years, 2-3 times less than in the Atlantic and Pacific oceans.
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10.
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