| 1. |
- Algurén, Beatrix, 1977, et al.
(författare)
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Functioning of stroke survivors--A validation of the ICF core set for stroke in Sweden.
- 2010
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Ingår i: Disability and rehabilitation. - : Informa UK Limited. - 0963-8288 .- 1464-5165. ; 32:7, s. 551-9
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To validate the body functions and activities and participation part of the extended International Classification of Functioning, Disability, and Health (ICF) core set for stroke with a Swedish population in the first 3 months post-stroke. METHOD: At 6 weeks and at 3 months post-stroke, stroke survivors were evaluated by 59 ICF categories of body functions, 59 categories of activities and participation from the stroke ICF core set (extended version). RESULTS: The study sample included 99 stroke survivors (54% women) with an average age of 72 years. Statistical significant problems were identified in 28 ICF categories of body functions and in 41 ICF categories of activities and participation at both time points, at 6 weeks and at 3 months. About 17 ICF categories were reported as problems in independent (i.e. modified Rankin Scale (mRS) < or =2) and about 34 categories in dependent (i.e. mRS > 2) stroke survivors. CONCLUSIONS: The results suggest a possible reduction of the stroke ICF core set from 59 to 28 categories of body functions and from 59 to 41 categories of activities and participation. Hence, feasibility of the core set for multiprofessional assessment increases and the core set might find more integration in clinical practice. The number of problems in mobility and self-care mainly distinguished between independent and dependent stroke survivors.
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| 2. |
- Antoniou, A. C., et al.
(författare)
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Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers : Implications for risk prediction
- 2010
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Ingår i: Cancer Research. - : American Association for Cancer Research. - 0008-5472 .- 1538-7445. ; 70:23, s. 9742-9754
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Tidskriftsartikel (refereegranskat)abstract
- The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 in STXBP4/COX11, and rs10941679 at 5p12, and reanalyzed the previous associations using additional carriers in a sample of 12,525 BRCA1 and 7,409 BRCA2 carriers. Additionally, we investigated potential interactions between SNPs and assessed the implications for risk prediction. The minor alleles of rs4973768 and rs10941679 were associated with increased breast cancer risk for BRCA2 carriers (per-allele HR = 1.10, 95% CI: 1.03-1.18, P = 0.006 and HR = 1.09, 95% CI: 1.01-1.19, P = 0.03, respectively). Neither SNP was associated with breast cancer risk for BRCA1 carriers, and rs6504950 was not associated with breast cancer for either BRCA1 or BRCA2 carriers. Of the 9 polymorphisms investigated, 7 were associated with breast cancer for BRCA2 carriers (FGFR2, TOX3, MAP3K1, LSP1, 2q35, SLC4A7, 5p12, P = 7 × 10-11 - 0.03), but only TOX3 and 2q35 were associated with the risk for BRCA1 carriers (P = 0.0049, 0.03, respectively). All risk-associated polymorphisms appear to interact multiplicatively on breast cancer risk for mutation carriers. Based on the joint genotype distribution of the 7 risk-associated SNPs in BRCA2 mutation carriers, the 5% of BRCA2 carriers at highest risk (i.e., between 95th and 100th percentiles) were predicted to have a probability between 80% and 96% of developing breast cancer by age 80, compared with 42% to 50% for the 5% of carriers at lowest risk. Our findings indicated that these risk differences might be sufficient to influence the clinical management of mutation carriers.
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| 3. |
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| 4. |
- Berntson, Martin, 1972-
(författare)
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Reformation and counter-culture in Maribo abbey
- 2010
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Ingår i: <em>Saint Birgitta, Syon and Vadstena. Papers from a Symposium in Stockholm 4-6 October 2007</em>. - Stockholm. ; , s. 216-226, s. 216-226
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Konferensbidrag (refereegranskat)
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| 5. |
- Berntson, Martin, 1972-
(författare)
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Vreta kloster och reformationen
- 2010
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Ingår i: <em>Fokus Vreta kloster. 17 nya rön om Sveriges äldsta kloster</em>.. - Stockholm : Statens historiska museum. ; , s. 369-383, s. 369-383
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 6. |
- Boesen, Jesper, et al.
(författare)
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The relation between types of assessment tasks and the mathematical reasoning students use
- 2010
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Ingår i: Educational Studies in Mathematics. - : Springer. - 0013-1954 .- 1573-0816. ; 75:1, s. 89-105
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Tidskriftsartikel (refereegranskat)abstract
- The relation between types of tasks and the mathematical reasoning used by students trying to solve tasks in a national test situation is analyzed. The results show that when confronted with test tasks that share important properties with tasks in the textbook the students solved them by trying to recall facts or algorithms. Such test tasks did not require conceptual understanding. In contrast, test tasks that do not share important properties with the textbook mostly elicited creative mathematically founded reasoning. In addition, most successful solutions to such tasks were based on this type of reasoning.
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| 7. |
- Browall, Maria, 1963, et al.
(författare)
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Health care staff's opinions about existential issues among patients with cancer.
- 2010
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Ingår i: Palliative & supportive care. - : Cambridge University Press. - 1478-9523 .- 1478-9515. ; 8:1, s. 59-68
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: The objective of this study was to explore health care staff's opinions about what existential issues are important to patients with cancer and staff's responsibility when existential issues are raised by patients. METHOD: Four focus group interviews were conducted with health care staff (N = 23) at an in-patient hospice, on an oncology ward, on a surgical ward, and with a palliative home health care team. The focus group interviews focused on two questions, first, about health care staff's opinions about patients' important existential questions and, second, about health care staff's responsibility when existential issues are raised by the patient. The interviews were tape-recorded, transcribed verbatim, and analyzed by qualitative content analysis into subcategories and categories. RESULTS: Four categories and 11 subcategories emerged from the first question. The first category, "life and death," was based on joy of living and thoughts of dying. The second category "meaning," consisted of acceptance, reevaluation, hope, and faith. The third category, "freedom of choice," consisted of responsibility and integrity, and the fourth and last category, "relationships and solitude," consisted of alleviation, dependency, and loss. One category emerged from the second question about the health care staff's responsibility, "to achieve an encounter," which was based on the subcategories time and space, attitudes, and invitation and confirmation. SIGNIFICANCE OF RESULTS: The strength of this study was that the findings were fairly congruent in different settings and in different geographical areas. Health care staff were aware of the importance of existential issues to patients. The existential issues, mentioned by health care staff, are similar to findings from studies conducted among patients, which is another strength of the present study. Health care staff are also confident about how to act when these issues are raised by the patients. The challenge for the future is to implement the findings from this study among health care staff in different settings.
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| 8. |
- Burman, Erik, 1968, et al.
(författare)
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Fictitious domain finite element methods using cut elements: I. A stabilized Lagrange multiplier method
- 2010
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Ingår i: Computer Methods in Applied Mechanics and Engineering. - : Elsevier BV. - 0045-7825 .- 1879-2138. ; 199:41-44, s. 2680-2686
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Tidskriftsartikel (refereegranskat)abstract
- We propose a fictitious domain method where the mesh is cut by the boundary. The primal solution is computed only up to the boundary; the solution itself is defined also by nodes outside the domain, but the weak finite element form only involves those parts of the elements that are located inside the domain. The multipliers are defined as being element-wise constant on the whole (including the extension) of the cut elements in the mesh defining the primal variable. Inf–sup stability is obtained by penalizing the jump of the multiplier over element faces. We consider the case of a polygonal domain with possibly curved boundaries. The method has optimal convergence properties.
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| 9. |
- Burman, Erik, 1968, et al.
(författare)
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Interior-penalty-stabilized Lagrange multiplier methods for the finite-element solution of elliptic interface problems
- 2010
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Ingår i: IMA Journal of Numerical Analysis. - : Oxford University Press (OUP). - 0272-4979 .- 1464-3642. ; 30:3, s. 870-885
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Tidskriftsartikel (refereegranskat)abstract
- In this paper we propose a class of jump-stabilized Lagrange multiplier methods for the finite-element solution of multidomain elliptic partial differential equations using piecewise-constant or continuous piecewise-linear approximations of the multipliers. For the purpose of stabilization we use the jumps in derivatives of the multipliers or, for piecewise constants, the jump in the multipliers themselves, across element borders. The ideas are illustrated using Poisson's equation as a model, and the proposed method is shown to be stable and optimally convergent. Numerical experiments demonstrating the theoretical results are also presented.
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| 10. |
- Cassel, Björn, et al.
(författare)
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Deflections of an implant-supported cantilever beam subjected to vertically directed loads : In vitro measurements in three dimensions using an optoelectronic method. II Analysis of methodological errors.
- 2010
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Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 22:6, s. 645-650
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Tidskriftsartikel (refereegranskat)abstract
- Aim: The aim of this study was to evaluate the accuracy, i.e. trueness (validity) and precision (repeatability) for load-dependent deflections in three dimensions of an implant-supported cantilever beam obtained with an optoelectronic motion analysis system compared with a well-known reference method.Materials and methods: A cantilever beam with a length of 22 mm (roughly corresponding to the width of two premolars) was screw-connected to an implant–abutment unit stiffly anchored in a steel plate. The positional changes of beam-end were measured when the beam-end step by step was subjected to four loads, 15.5–40.1 N. This measurement procedure was repeated to comprise six consecutive measurements. The trueness of the method was estimated by comparing the data obtained for vertical deflections with those from a reference method where a hydraulic test system was used to measure the load-deflection ratios of the same beam when subjected to the four mentioned vertical loads.Results: All applied transducer-mediated loads had accuracies (truenesses and repeatabilities below 0.05%). Also, the trueness and precision of the reference method, regarding both movements (deflections) of tested objects and magnitude of applied loads, were tested and found to be high, not exceeding 0.5%.The optoelectronic method however underestimated the smallest vertical deflections for the cantilever beam when compared with the data obtained from the reference method. The underestimation was 26.4%, 15.5% and 8.6% for loads 15.5, 26.6 and 32.6 N, respectively, while there was a slight overestimation of 1.2% for 40.1 N. The precision for the optoelectronic method was found to be for z-axis 1.8 μm, y-axis 3.8 μm and x-axis 1.9 μm.Conclusion: It can be concluded that the trueness (validity) for the optoelectronic method is very high for deflections above 143 μm. The precision (repeatability) of the optoelectronic method was found to be very high.
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