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Sökning: Nicaragua > (2005-2009)

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1.
  • Bucardo, Filemon, et al. (författare)
  • Genetic susceptibility to symptomatic norovirus infection in Nicaragua. : norovirus susceptibility in Nicaragua
  • 2009
  • Ingår i: Journal of medical virology. - : Wiley. - 1096-9071 .- 0146-6615. ; 81:4, s. 728-35
  • Tidskriftsartikel (refereegranskat)abstract
    • Host genetic resistance to Norovirus (NoV) has been observed in challenge and outbreak studies in populations from Europe, Asia, and USA. In this study, we have investigated if histo-blood group antigens can predict susceptibility to diarrhea caused by NoV in Nicaragua, Central America, and if this can be reflected in antibody-prevalence and titer to NoV among individuals with different histo-blood group antigen phenotypes. Investigation of 28 individuals infected with NoV and 131 population controls revealed 6% of non-secretors in the population and nil non-secretors among patients infected with NoV, suggesting that non-secretors may be protected against NoV disease in Nicaragua. Surprisingly, 25% of the population was Lewis negative (Le(a-b-)). NoV infections with genogroup I (GI) and GII occurred irrespective of Lewis genotype, but none of the Lewis a positive (Le(a + b-)) were infected. The globally dominating GII.4 virus infected individuals of all blood groups except AB (n = 5), while the GI viruses (n = 4) infected only blood type O individuals. Furthermore, O blood types were susceptible to infections with GI.4, GII.4, GII.7, GII.17, and GII.18-Nica viruses, suggesting that secretors with blood type O are susceptible (OR = 1.52) and non-secretors resistant. The overall antibody-prevalence to NoV GII.3 VLP was 62% with the highest prevalence among blood type B carriers (70%) followed by A (68%) and O (62%). All four investigated individuals carrying blood type AB were antibody-negative. Among secretors, 63% were antibody-positive compared to 33% among non-secretors (P = 0.151). This study extends previous knowledge about the histo-blood group antigens role in NoV disease in a population with different genetic background than North American and European.
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2.
  • Dahlblom, Kjerstin, 1950- (författare)
  • Home alone : sibling caretakers in León, Nicaragua
  • 2008
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Sibling caretaking, although common across time and cultures, has not been well researched from the carer’s point of view. In Nicaragua, ranked as one of the poorest countries in the Americas, sibling caretaking is common. The country’s historical background and its state of chronic poverty, widespread unemployment, loose family structures, and migration and mobility makes of the old practise of shared management child care a necessity. Households headed by sing¬le mothers constitute a particular Nica¬raguan charact¬eristic. Many children are expected to help in their own families and care for their siblings and other children living in their households. In its broadest sense sibling caretaking is a public health concern, and we conducted this study to widen the understanding of the phenomenon as it is represented in a setting undergoing a rapid social transition. The main objectives were to identify, describe and analyse the life situation of sibling caretakers in poor areas in León, Nicaragua, with focus on how they perceived it themselves. A combined qualitative and quantitative methodological design was used, mainly applying an ethnographic approach. A further ambition was to explore involvement of children in a participatory research process in accordance with the ‘Convention on the Rights of the Child’. The overall emotion expressed among the caretakers was pride, even if their situation often was characterized by stress and coping problems. They perceived their work as important for their families and they appreciated to fend for their siblings. Household work and nurturing of siblings were shaping the future lives of the caretakers and constituted part of their socialization. Even if many of these children achieve essential life skills as caretakers, they are at risk of falling behind as they grow older. Their long-term personal development is likely to be hampered by the obligations they have as caretakers. The carers' awareness of missing out on education was the most problematic issue for them. From a societal point of view, caretaking has negative consequences. The individual child is marginalised with limited access to basic education, contributing to overall low educational levels in Nicaragua. While the structuring conditions leading to sibling caretaking may be difficult to change, awareness of how these can affect children might make way for improvements in terms of access to school education and support from the society. The knowledge gained from this study should be further utilised to plan for interventions that take children’s perspectives into consideration.
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3.
  • Åsling Monemi, Kajsa, 1960- (författare)
  • The Impact of Violence Against Women on Child Growth, Morbidity and Survival : Studies in Bangladesh and Nicaragua
  • 2008
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The aim of this thesis was to explore the impact of physical, sexual and emotional violence against women of reproductive age and the level of controlling behaviour in marriage on child health and survival in two different cultural settings: Bangladesh and Nicaragua. Data were acquired from four quantitative community-based studies. In two studies, a cohort including a prospective two year follow-up of 3164 mother-infant pairs in rural Bangladesh was investigated. A third study was a case-referent study in Nicaragua including mothers of 110 cases of under-five deaths and 203 referents, and in a forth study an other cohort of 1048 rural Bangladeshi women and their 2691 children was followed until 5 years of age. Maternal exposure to any form of violence, including physical, sexual, emotional, and controlling behaviour was independently associated with lower body size at birth, increased risk of stunting and under-weight at 24 months of age, slower growth velocity during the first two years of life and a higher incidence of diarrhoeal episodes and respiratory tract infections. In the Nicaraguan setting, the children of women who experienced any history of physical violence had a two-fold increase in risk of death before the age of 5 years, and those whose mothers experienced both physical and sexual violence had a six-fold increase in risk of death. In Bangladesh, an association between violence against women and under-five mortality was found among daughters of educated mothers who were exposed to severe physical violence or a high level of controlling behaviour in marriage. In all four studies, lifetime violence experience among participating mothers was high (37-69%), and the timing was less relevant than the exposure to violence per se. In conclusion, this investigation revealed that violence against women severely affects child health and survival. The findings are especially relevant in a context of high level of child under-nutrition, morbidity and under-five mortality. Efforts for protecting women from all forms of violence are needed as part of the interventions for improved child health.
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4.
  • Wedel, Johan, 1962 (författare)
  • Religious Healing in Puerto Cabezas, Nicaragua
  • 2008
  • Ingår i: 33th Caribbean Studies Association (CSA) conference, San Andres, Colombia, May 26-30, 2008.
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • This paper inquires into the various forms of healing performed today among the Miskitu people of the Caribbean coast of Nicaragua. The Miskitu have a long history of relations with outsiders and with people of African origin. Miskitu cosmology and its ideas about illness and healing is today a mixture of indigenous, Afro-Caribbean, and Christian beliefs. Local healers constantly pick up new healing methods and ideas from other religious traditions in Central America, Mexico, and the Caribbean. The paper discusses how Miskitu healers, known as curanderos, sukias, and profetas, heal by relating sickness and suffering to a world of spirits which also makes reference to the plural cultural antecedences of contemporary Miskitu worldview.
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5.
  • Mendoza, J. A., et al. (författare)
  • Assessment of groundwater vulnerability in the Rio Artiguas basin, Nicaragua
  • 2006
  • Ingår i: Environmental Geology. - : Springer Science and Business Media LLC. - 0943-0105 .- 1432-0495. ; 50:4, s. 569-580
  • Tidskriftsartikel (refereegranskat)abstract
    • The Rio Artiguas basin in central Nicaragua shows a distinctive case of environmental deterioration due to anthropogenic activities. Heavy metals used in gold mining and other wastes are continuously released into the rivers, representing a threat to the water quality. This article aims to evaluate the groundwater intrinsic vulnerability in the Rio Artiguas basin and to provide information for sustainable use of water resources. The DRASTIC and GOD methods were used to analyse the relative pollution potential within the basin. DRASTIC was modified to include the degree of influence that geological structures have on the vulnerability. Moderate vulnerability areas cover most of the basin along stream valleys and lowlands, increasing downstream in the basin. The resulting vulnerability maps show that the limited groundwater resources are susceptible to surface water pollution as high vulnerability areas converge along the river valleys.
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6.
  • Wedel, Johan, 1962 (författare)
  • Spirit possession among the Miskitu of Nicaragua
  • 2008
  • Ingår i: Paper for the 10th EASA conference, Ljubljana, Slovenia, August 26-29, 2008..
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • The Miskitu people of Eastern Nicaragua are occasionally troubled by a spectacular illness called grisi siknis or "crazy sickness," said to be caused by spirits. This paper inquires into how Miskitu healers ritually transform the experience of the afflicted through an idiom of the spirit world.
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7.
  • Espinoza, F., et al. (författare)
  • Shifts of rotavirus G and P types in Nicaragua - 2001-2003
  • 2006
  • Ingår i: The Pediatric Infectious Disease Journal. - : Ovid Technologies (Wolters Kluwer Health). - 0891-3668 .- 1532-0987. ; 25:11, s. 1078-1080
  • Tidskriftsartikel (refereegranskat)abstract
    • The present study reports the diversity of rotavirus strains circulating in León, Nicaragua during three years. There was a shift of G and P genotypes with increment of one specific genotype during the second most important peak of diarrhea occurring in the beginning of every year. © 2006 Lippincott Williams & Wilkins, Inc.
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8.
  • Lebbad, Marianne, et al. (författare)
  • Dominance of Giardia assemblage B in León, Nicaragua.
  • 2008
  • Ingår i: Acta Tropica. - : Elsevier BV. - 0001-706X .- 1873-6254. ; 106:1, s. 44-53
  • Tidskriftsartikel (refereegranskat)abstract
    • Giardiasis is a major problem in León, Nicaragua, yet despite this no data are available regarding the prevalence of different Giardia genotypes in this area. To address this question, a molecular analysis of Giardia isolates from humans and dogs living in the same area in León, Nicaragua was performed. Giardia isolates from 119 Nicaraguan patients and 8 dogs were successfully genotyped using single and/or nested beta-giardin PCR with subsequent restriction length fragment polymorphism (RFLP) analysis. The analyses of human samples yielded 94 (79%) assemblage B isolates and 25 (21%) assemblage A isolates. Only the non-human-associated assemblages C and D were found in the dog samples. Sixteen isolates with assemblage A pattern, 26 isolates with assemblage B pattern and all dog isolates were further characterized by sequencing the nested beta-giardin PCR product and by molecular analyses of the glutamate dehydrogenase (gdh) gene. Within the study area the assemblage A isolates were highly genetically homogenous, showing only sub-genotypes A2 (n=3) or A3 (n=13) at the beta-giardin locus and AII only at the gdh locus while assemblage B showed a high genetic polymorphism at both loci. Seven different sub-genotypes were identified within 13 of the sequenced assemblage B beta-giardin isolates. The remaining 13 sequenced assemblage B-isolates appeared to contain several different variants of the beta-giardin gene since the chromatograms displayed one to seven double peaks. The gdh sequences showed an even higher polymorphism since only 2 of 26 assemblage B isolates were without double peaks. Two mixed infections between assemblage A and B were found when the gdh gene was analyzed. Polymorphisms were also observed in the dog-associated assemblages C and D, but to a lesser extent than in assemblage B.
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9.
  • Corriols, Marvin, et al. (författare)
  • Geophysical characterization of the Leon-Chinandega aquifer, Nicaragua
  • 2008
  • Ingår i: Hydrogeology Journal. - : Springer Science and Business Media LLC. - 1431-2174 .- 1435-0157. ; 16:2, s. 349-362
  • Tidskriftsartikel (refereegranskat)abstract
    • Electrical geophysical surveys in the mode of vertical electrical soundings (VES) and continuous vertical electrical soundings (CVES) were conducted in the Leon-Chinandega plains, northwestern Nicaragua, in order to obtain detailed information about the geometry of the different hydrogeological layers in the aquifer and depth to the basement. A total of 51 VES were carried out within the plains. The results show a complex structure towards the north east of the area, and the southwestern part of the plains presents a smoother stratification. The geoelectrical measurements and borehole information indicate that the basement topography is characterized by hills and deep valleys with highly variable basement depths. Fifty CVES where done in a smaller area in the center of the plain. The resistivity data yielded considerable information revealing the existence of two main geo-electrical units. The combined interpretation of geological and geophysical data shows an environment typical of sedimentary volcanic coastal plains. The information collected during this investigation provides valuable data for estimating the fresh-water resources of the Leon-Chinandega aquifer system and for development of a groundwater management plan.
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10.
  • Mendoza, J. A., et al. (författare)
  • Hydrogeological and hydrochemical features of an area polluted by heavy metals in central Nicaragua
  • 2006
  • Ingår i: Hydrogeology Journal. - : Springer Science and Business Media LLC. - 1431-2174 .- 1435-0157. ; 14:5, s. 777-784
  • Tidskriftsartikel (refereegranskat)abstract
    • Geophysical and hydrochemical surveys were used to investigate the hydrogeological conditions in one of the Rio Sucio microbasins, in central Nicaragua. Zones of vertical structures (i.e. fractures and quartz veins) and weathering were mapped using Continuous Vertical Electrical Soundings (CVES), as such zones are of major importance for groundwater transport. Water from the springs was analysed to determine concentrations of major ions and heavy metals. Low ion concentrations and 180 analyses indicate that the springs occur close to their recharge areas and there is a relatively rapid groundwater circulation. Mercury (Hg) content in the springs was low, while comparatively high amounts of lead (Pb) were found. The results presented here demonstrate the important function of weathering and tectonics in the occurrence of groundwater systems in the basin. Hg and Pb found in the springs' water reveal the existence of an increase in pollution sources disseminating in the area. More than 100 years of using mercury in the gold-mining industry and releasing wastes into rivers has affected water quality and ecosystems. Further investigations are needed in this area to determine the groundwater vulnerability to this pollution as this resource may be needed in the future.
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