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Träfflista för sökning "L773:0250 7005 OR L773:1791 7530 ;srt2:(1995-1999)"

Search: L773:0250 7005 OR L773:1791 7530 > (1995-1999)

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51.	Palm, Stig, 1964, et al. (author) Effects of the alpha-particle emitter At-211 and low-dose-rate gamma-radiation on the human cell line Colo-205 as studied with a growth assay 1998 In: Anticancer Res. - 0250-7005. ; 18:3A, s. 1671-6 Journal article (peer-reviewed)abstract BACKGROUND: The aim of this study was to investigate the biological effect of the alpha-particle-emitting isotope astatine-211 on the human cell line Colo-205 and to compare it with that of low-dose-rate gamma-radiation. MATERIALS AND METHODS: Plastic (PMMA) rotating phantoms were constructed, allowing precise dosimetry on a cellular level for both types of radiation. Growth assays using 96-well plates were used to estimate apparent cell survival for the two types of radiation. From this, the relative biological effect (RBE) could be estimated. RESULTS: Irradiation of the cells with 211At resulted in an RBE of 25.1 +/- 6.7 at 37% survival, and 17.3 +/- 2.5 at 10% survival, when compared with low-dose-rate gamma-irradiation. The absorbed dose at 37% survival, 0.12 Gy, corresponds to 2.2 traversals of alpha-particles through the cell nuclei. For cells irradiated with gamma-radiation (1 and 2 Gy), an apparent cell survival above unity was observed up to 50 hours post-irradiation, indicating a possible radiation hormesis effect. CONCLUSIONS: The RBE of 211At found in this growth-assay study was significantly higher than previously presented values. The difference might be due to the use of low-dose-rate gamma-radiation as reference. The RBE presented here could prove valuable when evaluating 211At-labelled compounds for radiotherapy.
52.	Rubio, CA, et al. (author) A comparative study between the gastric mucosa of west Canadians and other dwellers of the Pacific Basin 1998 In: Anticancer research. - 0250-7005. ; 18:4A, s. 2463-2470 Journal article (peer-reviewed)
53.	Rubio, CA, et al. (author) Adenocarcinoma of the cecum with Crohn's-like features in baboons 1998 In: Anticancer research. - 0250-7005. ; 18:2A, s. 1143-1147 Journal article (peer-reviewed)
54.	Rubio, CA, et al. (author) Atypical mitoses in colectomy specimens from patients with long standing ulcerative colitis 1997 In: Anticancer research. - 0250-7005. ; 17:4A, s. 2721-2726 Journal article (peer-reviewed)
55.	Rubio, CA, et al. (author) Cytotoxic intraepithelial lymphocytes in colorectal polyps and carcinomas 1999 In: Anticancer research. - 0250-7005. ; 19:4B, s. 3221-3227 Journal article (peer-reviewed)
56.	Rubio, CA (author) Differences in angiogenesis and collagenesis between exophytic and flat adenomas of the colorectal mucosa 1997 In: Anticancer research. - 0250-7005. ; 17:1B, s. 737-741 Journal article (peer-reviewed)
57.	Rubio, CA, et al. (author) Ethnic or environmental differences in disparate geographic regions may influence the histology of flat colorectal neoplasias 1998 In: Anticancer research. - 0250-7005. ; 18:1B, s. 651-655 Journal article (peer-reviewed)
58.	Rubio, CA, et al. (author) Gastric adenocarcinomas in displaced mucosal glands 1999 In: Anticancer research. - 0250-7005. ; 19:3B, s. 2381-2385 Journal article (peer-reviewed)
59.	Rubio, CA, et al. (author) Histologic phenotypes of colonic carcinoma in Sweden and in Japan 1998 In: Anticancer research. - 0250-7005. ; 18:4A, s. 2649-2655 Journal article (peer-reviewed)
60.	Rubio, CA, et al. (author) Non-polypoid colorectal neoplasias: a multicentric study 1999 In: Anticancer research. - 0250-7005. ; 19:3B, s. 2361-2364 Journal article (peer-reviewed)

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Type of publication: journal article (70)

Type of content: peer-reviewed (67); other academic/artistic (3)

Author/Editor: Strang, P (9); Rubio, CA (9); Hultborn, Ragnar, 19 ... (8); Bergstrom, R (6); Lindmark, G (4); Nordstrom, B (4); show more...; Linder, S (4); Munck-Wikland, E (4); Bergh, J (3); Glimelius, B (3); Tribukait, B (3); Bergqvist, M. (3); Larsson, A (3); Sundqvist, KG (3); Auer, G (3); Brattstrom, D. (3); Brodin, O (3); Hesselius, P (3); Wagenius, G (3); Kato, Y. (2); Nilsson, A (2); Taguchi, Y. (2); Linde, A (2); Hanson, C (2); Hansson, J. (2); Jaramillo, E (2); Kawaguchi, M (2); Hogmo, A. (2); Öberg, Kjell (2); Lewensohn, R. (2); Nilsson, S. (2); Sundin, Anders (2); Linder, C (2); Watanabe, M. (2); Nannmark, Ulf, 1958 (2); Ranstam, J (2); Lindholm, J (2); Lindahl, B (2); Lindgren, A. (2); Graf, Wilhelm (2); Edgren, M. (2); Andolf, E (2); Mahteme, Haile (2); Ingvar, C (2); Pahlman, L (2); Slezak, P (2); Willen, R. (2); Rosenberg, L (2); Holmertz, J (2); Heiden, T (2); show less...

University: Karolinska Institutet (46); Uppsala University (17); University of Gothenburg (9); Linköping University (2); Umeå University (1); Jönköping University (1); show more...; Lund University (1); Södertörn University (1); Chalmers University of Technology (1); show less...

Language: English (70)

Research subject (UKÄ/SCB): Medical and Health Sciences (14); Natural sciences (4)

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