| 1. |
- Burman, Pia, et al.
(författare)
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Deaths Among Adult Patients With Hypopituitarism: Hypocortisolism During Acute Stress, and De Novo Malignant Brain Tumors Contribute to an Increased Mortality
- 2013
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Ingår i: Journal of Clinical Endocrinology & Metabolism. - : The Endocrine Society. - 0021-972X .- 1945-7197. ; 98:4, s. 1466-1475
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Tidskriftsartikel (refereegranskat)abstract
- Context: Patients with hypopituitarism have an increased standardized mortality rate. The basis for Objective: To investigate in detail the cause of death in a large cohort of patients with hypopituitarism Design and Methods: All-cause and cause-specific mortality in 1286 Swedish patients with Main Outcome Measures: Standardized mortality ratios (SMR) were calculated, with stratification for Results: An excess mortality was found, 120 deaths vs 84.3 expected, SMR 1.42 (95% confidence Conclusion: Two important causes of excess mortality were identified: first, adrenal crisis in response
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| 2. |
- Ekman, Inger, 1952, et al.
(författare)
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Can treatment with ACE-inhibitors in elderly patients with moderate to severe heart failure be improved by a nurse-monitored structured care program?
- 2003
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Ingår i: Heart & Lung. - 0147-9563. ; 32:1, s. 3-9
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Tidskriftsartikel (refereegranskat)abstract
- Can treatment with angiotensin-converting enzyme inhibitors in elderly patients with moderate to severe chronic heart failure be improved by a nurse-monitored structured care program? A randomized controlled trial. OBJECTIVE: The purpose of this study was to examine whether a nurse-monitored structured care program resulted in a more effective use of angiotensin-converting enzyme (ACE) inhibitors in elderly patients compared with standard care in patients with chronic heart failure (CHF). METHODS: Hospitalized patients were screened to identify individuals with CHF, age more than 65 years, New York Heart Association classification III to IV, and no contraindications to ACE inhibitor treatment. One hundred forty-five patients were randomized to a nurse-monitored structured care program that included uptitration of enalapril to a target dose of 10 mg twice a day or to standard care. Six-month follow-up data were collected. RESULTS: The mean age of the randomized patients was 81 years. Although the proportion of patients treated with an ACE inhibitor did not differ between structured care (70%) and standard care (64%), the number of patients with the target ACE inhibitor dose was significantly higher in the structured care group (26% versus 11% in the standard care group; P <.018). Treatment had to be discontinued in 26% of the patients because of adverse effects. CONCLUSION: The patients in this study were older than in previous intervention studies and had considerable comorbidity and reduced tolerance for ACE inhibitors. ACE inhibitor treatment was underused but improved with the structured care program, although achieved treatment levels were below those in the large intervention trials in patients with CHF.
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| 3. |
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Learning Regional Innovation : Scandinavian Models
- 2011
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- While the distinction between science driven and experience driven innovation is well known and much commented on, the point that experience driven innovation demands broad participation, not only within the individual enterprise but across the whole labour market, is less well recognized. When innovation first started to attract attention, the focus was on how to create innovation. In the light of the current crisis, a new question has entered the agenda: how to create socially responsible innovation?Participation and social responsibility in innovation are the core themes of this book. The main argument is that both are issues of organization and not of, say, ethics, or the enforcement of other forms of obligations on individual actors. The need is for a democratization of innovation that can make innovation open to broad participation, scrutiny from many positions, and influence from different interest groups without, however, losing the forward momentum.The organization of processes that can carry forward socially responsible innovation is, in turn, dependent upon public-private co-operation. This needs, however, to be a co-operation that expresses itself in terms of joint development processes, not traditional regulation.Combining experience driven innovation, broad participation and development oriented public-private co-operation, this book demonstrates that Scandinavia offers a unique arena of experience. It is a further argument that insofar as there is a 'systems response' to the present crisis, it lies in the direction of broader diffusion of this kind of pattern.Since the arguments of this book are built on practical experience, it does not seek to establish a set of abstract 'musts' without views on implementation, but rather points at the processes that can be initiated to create movement in the right direction.
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| 4. |
- Angelis, Stavros, et al.
(författare)
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Research Community Evaluation Report : Europeana Cloud Deliverable 1.7
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This report deals with three Evaluation Workshops organized by ATHENA R.C that took place as part of research undertaken in Work Package 1 of the Europeana Cloud (eCloud) project (2013-16). The workshops were linked to WP3 iterative development cycle, and intended to provide feedback regarding the usefulness, as against usability, of tools and service prototypes within Europeana Cloud and their fitness-for-purpose with regard to the requirements analysis and user-centred design of Europeana Research.
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| 5. |
- Angelis, Stavros, et al.
(författare)
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User Requirements Analysis and Case Studies Report. Content Strategy Report. : Europeana Cloud Deliverable 1.3 and 1.6: User Requirements Analysis and Case Studies Report (1.3) and Content Strategy Report (1.6)
- 2015
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The present Deliverable (1.3) comprises of two joint reports: former Deliverable 1.3 (User Requirements and Case Studies report) and Deliverable 1.6 (Content Strategy Report). As a product of a multi-scale, interdisciplinary effort, Deliverable 1.3 (User Requirements and Case Studies report / Content Strategy Report) employs a multi-faceted approach to make sense of the information needs and behaviour of Humanities and Social Sciences researchers both within and outside the Europeana ecosystem, while achieving profound understanding of the ways these communities interact with existing Europeana content and metadata. Through extensive and widely-levelled empirical research (Case Studies, Web Survey, Interviews, Focus Groups) complimented by thorough desk research (Literature review, study of particular thematic areas), and building on work previously conducted in the context of other Digital Humanities Research Infrastructures (DARIAH, EHRI, ARIADNE, NeDiMAH) Work Package 1 managed to reach a long list of non-prioritized User Requirements as well as a set of flexible Content Recommendations for the upcoming development of Europeana Research.
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| 6. |
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| 7. |
- Axelson, Henrik, et al.
(författare)
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Health financing for the poor produces promising short-term effects on utilization and out-of-pocket expenditure: evidence from Vietnam
- 2009
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Ingår i: International Journal for Equity in Health. - : Springer Science and Business Media LLC. - 1475-9276. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- Background: Vietnam introduced the Health Care Fund for the Poor in 2002 to increase access to health care and reduce the financial burden of health expenditure faced by the poor and ethnic minorities. It is often argued that effects of financing reforms take a long time to materialize. This study evaluates the short-term impact of the program to determine if pro-poor financing programs can achieve immediate effects on health care utilization and out-of-pocket expenditure. Method: Considering that the program is a non-random policy initiative rolled out nationally, we apply propensity score matching with both single differences and double differences to data from the Vietnam Household Living Standards Surveys 2002 (pre-program data) and 2004 (first post-program data). Results: We find a small, positive impact on overall health care utilization. We find evidence of two substitution effects: from private to public providers and from primary to secondary and tertiary level care. Finally, we find a strong negative impact on out-of-pocket health expenditure. Conclusion: The results indicate that the Health Care Fund for the Poor is meeting its objectives of increasing utilization and reducing out-of-pocket expenditure for the program's target population, despite numerous administrative problems resulting in delayed and only partial implementation in most provinces. The main lessons for low and middle-income countries from Vietnam's early experiences with the Health Care Fund for the Poor are that it managed to achieve positive outcomes in a short time-period, the need to ensure adequate and sustained funding for targeted programs, including marginal administrative costs, develop effective targeting mechanisms and systems for informing beneficiaries and providers about the program, respond to the increased demand for health care generated by the program, address indirect costs of health care utilization, and establish and maintain routine and systematic monitoring and evaluation mechanisms.
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| 8. |
- Benardou, Agiatis, et al.
(författare)
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State of the art report on digital research practices, tools and scholarly content use : Deliverable D1.2
- 2013
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This document constitutes desk research to analyse the current situation related to digital research practices, tools and content for the humanities and social sciences research communities and it comprises of three Milestones submitted separately in the course of the first nine months of the Project, each corresponding to digital research practices, tools and content respectively. Moreover, this report will serve as an exploratory stage which will provide the basis for the confirmation stage, that is the web survey undertaken within Task 1.3, relying heavily on work previously presented in Deliverable 1.1 (Research Communities Identification and Definition Report), in which the humanities and social sciences research communities were largely identified. The Research Communities Web Survey (T.1.3.4), which has been completed and is currently being processed, encompasses - amongst others -questions pertaining to the activities undertaken by Humanities and Social Sciences researchers, as well as questions regarding the use of content and metadata. This current document provides the background work which guided the design of the Web Survey and is meant to complement the related Web Survey findings which will comprise the User Requirements and Case Studies Analysis report, D1.3. Moreover, this work draws from and complements Deliverable 1.5 (Case Studies Expert Forum Report. The present desk research seeks to analyse the current situation related to digital research practices, tools and content for the humanities and social sciences research community, and will serve as an exploratory stage which will provide the basis for the confirmatory stage, that is the Content Strategy and User Requirements reports, due later on in the Project.
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| 9. |
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| 10. |
- Björk, Jonas, et al.
(författare)
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Predicting participation in the population-based Swedish cardiopulmonary bio-image study (SCAPIS) using register data
- 2017
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Ingår i: Scandinavian Journal of Public Health. - : SAGE Publications. - 1403-4948 .- 1651-1905. ; 45, s. 45-49
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Tidskriftsartikel (refereegranskat)abstract
- Aims: To illustrate the importance of access to register data on determinants and predictors of study participation to assess validity of population-based studies. In the present investigation, we use data on sociodemographic conditions and disease history among individuals invited to the Swedish cardiopulmonary bio-image study (SCAPIS) in order to establish a model that predicts study participation. Methods: The pilot study of SCAPIS was conducted within the city of Gothenburg, Sweden, in 2012, with 2243 invited individuals (50% participation rate). An anonymous data set for the total target population (n = 24,502) was made available by register authorities (Statistics Sweden and the National Board of Health and Welfare) and included indicators of invitation to and participation in SCAPIS along with register data on residential area, sociodemographic variables, and disease history. Propensity scores for participation were estimated using logistic regression. Results: Residential area, country of birth, civil status, education, occupational status, and disposable income were all associated with participation in multivariable models. Adding data on disease history only increased overall classification ability marginally. The associations with disease history were diverse with some disease groups negatively associated with participation whereas some others tended to increase participation. Conclusions: The present investigation stresses the importance of a careful consideration of selection effects in population-based studies. Access to detailed register data also for non-participants can in the statistical analysis be used to control for selection bias and enhance generalizability, thereby making the results more relevant for policy decisions.
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