| 1. |
- Moberg, Christina, et al.
(författare)
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De unga gör helt rätt när de stämmer staten
- 2022
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Ingår i: Aftonbladet. - 1103-9000.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav
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| 2. |
- Chirumalla, Koteshwar, et al.
(författare)
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The influence of different media instructions on solving a procedural task
- 2015
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Ingår i: ICED 15, Vol. 11. - 9781904670742
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Konferensbidrag (refereegranskat)abstract
- This study investigates the influence of different forms of media instructions on the process and outcomes of completing a specific procedural task. The experiment was conducted with four student groups having an education in the area of Information Design. In the experiment four media instructions - text only, text plus drawings, a series of pictures and video with narration - were considered. The findings show that the type of media has an influence on the ability to solve a procedural task and on group interaction and the way groups solve a task. Compared with the other instructions, video instruction triggered a different interaction and behavioural pattern during assembly. Participants considered both video and picture instructions as more usable in terms of facilitating the ability to understand, select and apply possible solutions to a given task. However, the video medium showed little influence on dialogue in the group during assembly. The instructions, such as text plus drawings, pictures and video had a similar influence on task performance times, whereas text instructions took three times longer to implement than other instructions.
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| 3. |
- Eriksson, Daniel, et al.
(författare)
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Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1
- 2018
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Ingår i: The Journal of clinical endocrinology and metabolism. - : The Endocrine Society. - 1945-7197 .- 0021-972X. ; 103:1, s. 179-186
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Tidskriftsartikel (refereegranskat)abstract
- Context: Autoimmune polyendocrine syndrome type 1 (APS1) is a monogenic disorder that features autoimmune Addison disease as a major component. Although APS1 accounts for only a small fraction of all patients with Addison disease, early identification of these individuals is vital to prevent the potentially lethal complications of APS1.Objective: To determine whether available serological and genetic markers are valuable screening tools for the identification of APS1 among patients diagnosed with Addison disease.Design: We systematically screened 677 patients with Addison disease enrolled in the Swedish Addison Registry for autoantibodies against interleukin-22 and interferon-α4. Autoantibody-positive patients were investigated for clinical manifestations of APS1, additional APS1-specific autoantibodies, and DNA sequence and copy number variations of AIRE.Results: In total, 17 patients (2.5%) displayed autoantibodies against interleukin-22 and/or interferon-α4, of which nine were known APS1 cases. Four patients previously undiagnosed with APS1 fulfilled clinical, genetic, and serological criteria. Hence, we identified four patients with undiagnosed APS1 with this screening procedure.Conclusion: We propose that patients with Addison disease should be routinely screened for cytokine autoantibodies. Clinical or serological support for APS1 should warrant DNA sequencing and copy number analysis of AIRE to enable early diagnosis and prevention of lethal complications.
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| 4. |
- Eriksson, Olof, et al.
(författare)
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The Positron Emission Tomography ligand [11C]5-Hydroxy-Tryptophan can be used as a surrogate marker for the human endocrine pancreas
- 2014
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Ingår i: Diabetes. - : American Diabetes Association. - 0012-1797 .- 1939-327X. ; 63:10, s. 3428-3437
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Tidskriftsartikel (refereegranskat)abstract
- In humans a well-developed serotonin system is localized to the pancreatic islets while being absent in exocrine pancreas. Assessment of pancreatic serotonin biosynthesis could therefore be used to estimate the human endocrine pancreas. Proof of concept was tested in a prospective clinical trial by comparisons of type 1 diabetic (T1D) patients, with extensive reduction of beta cells, with healthy volunteers (HV).C-peptide negative (i.e. insulin-deficient) T1D subjects (n=10) and HV (n=9) underwent dynamic Positron Emission Tomography with the radiolabeled serotonin precursor [(11)C]5-Hydroxy-Tryptophan ([(11)C]5-HTP).A significant accumulation of [(11)C]5-HTP was obtained in the pancreas of the HV, with large inter-individual variation. A substantial and highly significant reduction (66%) in the pancreatic uptake of [(11)C]5-HTP in T1D subjects was observed, and this was most evident in the corpus and caudal regions of the pancreas where beta-cells normally are the major constituent of the islets.[(11)C]5-HTP retention in the pancreas was reduced in T1D compared to non-diabetic subjects. Accumulation of [(11)C]5-HTP in the pancreas of both HV and subjects with T1D were in agreement with previously reported morphological observations on the beta cell volume implying that [(11)C]5-HTP retention is a useful non-invasive surrogate marker for the human endocrine pancreas.
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| 5. |
- Huang, Yezi, et al.
(författare)
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Enabling DSL and Radio on the Same Copper Pair
- 2015
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Ingår i: 2015 IEEE International Conference on Communications (ICC). - 9781467364324 ; , s. 1031-1035
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Konferensbidrag (refereegranskat)abstract
- To increase indoor coverage for mobile services, we propose a residential small cell infrastructure making use of the existing copper plant. The system is cabinet-based, collocated with VDSL2 and uses small pieces of spectrum next to VDSL2. Inspired by the Ericsson Radio Dot System, it challenges the femtocell paradigm offering full macro functionality in the small cells. An interesting service potential is offered albeit the added mobile traffic capacity is moderate as it is limited by the copper fronthaul.
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| 6. |
- Huang, Yezi, et al.
(författare)
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LTE Over Copper - Potential and Limitations
- 2015
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Ingår i: 2015 IEEE 26th Annual International Symposium on Personal, Indoor, and Mobile Radio Communications (PIMRC). - 9781467367820 ; , s. 1339-1343
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Konferensbidrag (refereegranskat)abstract
- The densification of mobile networks in order to meet increased capacity demands is ongoing, needed and costly. A few papers have been published based on the insight that the fixed broadband networks offer a multitude of sites, for instance our homes, for potential small cell deployment providing backhaul capacity and power without site costs. However, in order to reach economical large-scale benefits, we explore the case when radio systems are deployed in coexistence with DSL. In this paper, we establish the feasibility of such a concept under constraints invoked by state-of-the-art and emerging systems (3GPP, VDSL2 and G.fast) and make statements about the required architecture. We also point out that the enthusiasm of previously published results should be lowered a notch.
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| 7. |
- Huang, Yezi, et al.
(författare)
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Time-Domain Precoding for LTE-over-Copper Systems
- 2016
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Ingår i: 2016 IEEE International Conference on Communications (ICC). - 9781479966646 - 9781479966653 ; , s. 1-6
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Konferensbidrag (refereegranskat)abstract
- Crosstalk cancellation is a crucial issue for traditional digital subscriber line systems. For LTE-over-copper systems, however, the need for crosstalk cancellation varies depending on the analog fronthauling architecture and its parameters. A crosstalk handler that is decoupled as much as possible from the rest of the system architecture is thus preferred. Therefore, we propose a time-domain precoding scheme specifically in downstream direction to separate the precoding unit from the LTE signal flow, and perform crosstalk cancellation in an on-demand manner. Estimation of all direct and crosstalk paths is assisted by LTE cell-specific reference signals. The time-domain precoder transforms the interference channel into a crosstalk-free channel with identical direct paths, which allows for low-complexity inter-symbol interference mitigation. We evaluate the concept in terms of signal-to-noise ratio provided for LTE signals using measured wireline channel data.
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| 8. |
- Joffrin, E., et al.
(författare)
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Overview of the JET preparation for deuterium-tritium operation with the ITER like-wall
- 2019
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 59:11
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Forskningsöversikt (refereegranskat)abstract
- For the past several years, the JET scientific programme (Pamela et al 2007 Fusion Eng. Des. 82 590) has been engaged in a multi-campaign effort, including experiments in D, H and T, leading up to 2020 and the first experiments with 50%/50% D-T mixtures since 1997 and the first ever D-T plasmas with the ITER mix of plasma-facing component materials. For this purpose, a concerted physics and technology programme was launched with a view to prepare the D-T campaign (DTE2). This paper addresses the key elements developed by the JET programme directly contributing to the D-T preparation. This intense preparation includes the review of the physics basis for the D-T operational scenarios, including the fusion power predictions through first principle and integrated modelling, and the impact of isotopes in the operation and physics of D-T plasmas (thermal and particle transport, high confinement mode (H-mode) access, Be and W erosion, fuel recovery, etc). This effort also requires improving several aspects of plasma operation for DTE2, such as real time control schemes, heat load control, disruption avoidance and a mitigation system (including the installation of a new shattered pellet injector), novel ion cyclotron resonance heating schemes (such as the three-ions scheme), new diagnostics (neutron camera and spectrometer, active Alfven eigenmode antennas, neutral gauges, radiation hard imaging systems...) and the calibration of the JET neutron diagnostics at 14 MeV for accurate fusion power measurement. The active preparation of JET for the 2020 D-T campaign provides an incomparable source of information and a basis for the future D-T operation of ITER, and it is also foreseen that a large number of key physics issues will be addressed in support of burning plasmas.
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| 9. |
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| 10. |
- Lindgren, Johan, et al.
(författare)
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Soft-tissue evidence for homeothermy and crypsis in a Jurassic ichthyosaur
- 2018
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 564:7736, s. 359-
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Tidskriftsartikel (refereegranskat)abstract
- Ichthyosaurs are extinct marine reptiles that display a notable external similarity to modern toothed whales. Here we show that this resemblance is more than skin deep. We apply a multidisciplinary experimental approach to characterize the cellular and molecular composition of integumental tissues in an exceptionally preserved specimen of the Early Jurassic ichthyosaur Stenopterygius. Our analyses recovered still-flexible remnants of the original scaleless skin, which comprises morphologically distinct epidermal and dermal layers. These are underlain by insulating blubber that would have augmented streamlining, buoyancy and homeothermy. Additionally, we identify endogenous proteinaceous and lipid constituents, together with keratinocytes and branched melanophores that contain eumelanin pigment. Distributional variation of melanophores across the body suggests countershading, possibly enhanced by physiological adjustments of colour to enable photoprotection, concealment and/or thermoregulation. Convergence of ichthyosaurs with extant marine amniotes thus extends to the ultrastructural and molecular levels, reflecting the omnipresent constraints of their shared adaptation to pelagic life.
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