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  • Isaksson, Johan, et al. (author)
  • Exploring possible association between DβH genotype (C1021T), early onset of conduct disorder and psychopathic traits in juvenile delinquents.
  • 2016
  • In: European Archives of Psychiatry and Clinical Neuroscience. - : Springer Science and Business Media LLC. - 0940-1334 .- 1433-8491. ; 266:8, s. 771-773
  • Journal article (peer-reviewed)abstract
    • Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Isaksson, Johan (1)
af Klinteberg, Britt (1)
Oreland, Lars (1)
Koposov, Roman A. (1)
Grigorenko, Elena L. (1)
Ruchkin, Vladislav, ... (1)
University
Uppsala University (1)
Karolinska Institutet (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
2016 (1)

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