SwePub
Tyck till om SwePub Sök här!
Sök i LIBRIS databas

  Extended search

onr:"22116373"
 

Search: onr:"22116373" > Evaluation of a can...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)

Osorio, A. (author)
Milne, R L (author)
Pita, G. (author)
show more...
Peterlongo, P. (author)
Heikkinen, T. (author)
Simard, J. (author)
Chenevix-Trench, G. (author)
Spurdle, A B (author)
Beesley, J. (author)
Chen, X. (author)
Healey, S. (author)
Neuhausen, S L (author)
Ding, Y C (author)
Couch, F J (author)
Wang, X. (author)
Lindor, N. (author)
Manoukian, S. (author)
Barile, M. (author)
Viel, A. (author)
Tizzoni, L. (author)
Szabo, C I (author)
Foretova, L. (author)
Zikan, M. (author)
Claes, K. (author)
Greene, M H (author)
Mai, P. (author)
Rennert, G. (author)
Lejbkowicz, F. (author)
Barnett-Griness, O. (author)
Andrulis, I L (author)
Ozcelik, H. (author)
Weerasooriya, N. (author)
Gerdes, A-M (author)
Thomassen, M. (author)
Cruger, D G (author)
Caligo, M A (author)
Friedman, E. (author)
Kaufman, B. (author)
Laitman, Y. (author)
Cohen, S. (author)
Kontorovich, T. (author)
Gershoni-Baruch, R. (author)
Dagan, E. (author)
Jernstrom, H. (author)
Stenmark Askmalm, Marie (author)
Arver, B. (author)
Malmer, B. (author)
Domchek, S M (author)
Nathanson, K L (author)
Brunet, J. (author)
Cajal, T. Ramon y (author)
Yannoukakos, D. (author)
Hamann, U. (author)
Hogervorst, F B L (author)
Verhoef, S. (author)
Gomez Garcia, E B (author)
Wijnen, J T (author)
van den Ouweland, A. (author)
Easton, D F (author)
Peock, S. (author)
Cook, M. (author)
Oliver, C T (author)
Frost, D. (author)
Luccarini, C. (author)
Evans, D G (author)
Lalloo, F. (author)
Eeles, R. (author)
Pichert, G. (author)
Cook, J. (author)
Hodgson, S. (author)
Morrison, P J (author)
Douglas, F. (author)
Godwin, A K (author)
Sinilnikova, O M (author)
Barjhoux, L. (author)
Stoppa-Lyonnet, D. (author)
Moncoutier, V. (author)
Giraud, S. (author)
Cassini, C. (author)
Olivier-Faivre, L. (author)
Revillion, F. (author)
Peyrat, J-P (author)
Muller, D. (author)
Fricker, J-P (author)
Lynch, H T (author)
John, E M (author)
Buys, S. (author)
Daly, M. (author)
Hopper, J L (author)
Terry, M B (author)
Miron, A. (author)
Yassin, Y. (author)
Goldgar, D. (author)
Singer, C F (author)
Gschwantler-Kaulich, D. (author)
Pfeiler, G. (author)
Spiess, A-C (author)
v. O. Hansen, Thomas (author)
T. Johannsson, O. (author)
Kirchhoff, T. (author)
Offit, K. (author)
Kosarin, K. (author)
Piedmonte, M. (author)
C. Rodriguez, G. (author)
Wakeley, K. (author)
F. Boggess, J. (author)
Basil, J. (author)
E. Schwartz, P. (author)
V. Blank, S. (author)
E. Toland, A. (author)
Montagna, M. (author)
Casella, C. (author)
N. Imyanitov, E. (author)
Allavena, A. (author)
K. Schmutzler, R. (author)
Versmold, B. (author)
Engel, C. (author)
Meindl, A. (author)
Ditsch, N. (author)
Arnold, N. (author)
Niederacher, D. (author)
Deissler, H. (author)
Fiebig, B. (author)
Varon-Mateeva, R. (author)
Schaefer, D. (author)
G. Froster, U. (author)
Caldes, T. (author)
de la Hoya, M. (author)
McGuffog, L. (author)
C. Antoniou, A. (author)
Nevanlinna, H. (author)
Radice, P. (author)
Benitez, J. (author)
show less...
 (publisher)
 (publisher)
show more...
 (publisher)
show less...
2009
2009
English.
In: British Journal of Cancer. - 0007-0920. ; 101:12, 2048-2054
  • swepub:Mat__t
Abstract Subject headings
Close  
  • BACKGROUND: In this study we aimed to evaluate the role of a SNP in intron I of the ERCC4 gene (rs744154), previously reported to be associated with a reduced risk of breast cancer in the general population, as a breast cancer risk modifier in BRCA1 and BRCA2 mutation carriers. METHODS: We have genotyped rs744154 in 9408 BRCA1 and 5632 BRCA2 mutation carriers from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) and assessed its association with breast cancer risk using a retrospective weighted cohort approach. RESULTS: We found no evidence of association with breast cancer risk for BRCA1 (per-allele HR: 0.98, 95% CI: 0.93-1.04, P = 0.5) or BRCA2 (per-allele HR: 0.97, 95% CI: 0.89-1.06, P = 0.5) mutation carriers. CONCLUSION: This SNP is not a significant modifier of breast cancer risk for mutation carriers, though weak associations cannot be ruled out.

Subject headings

Medical and Health Sciences  (hsv)
Medicin och hälsovetenskap  (hsv)
MEDICINE  (svep)
MEDICIN  (svep)

Keyword

BRCA1; BRCA2; ERCC4; breast cancer

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Find more in SwePub

By the author/editor
Osorio, A.
Milne, R L
Pita, G.
Peterlongo, P.
Heikkinen, T.
Simard, J.
show more...
Chenevix-Trench, ...
Spurdle, A B
Beesley, J.
Chen, X.
Healey, S.
Neuhausen, S L
Ding, Y C
Couch, F J
Wang, X.
Lindor, N.
Manoukian, S.
Barile, M.
Viel, A.
Tizzoni, L.
Szabo, C I
Foretova, L.
Zikan, M.
Claes, K.
Greene, M H
Mai, P.
Rennert, G.
Lejbkowicz, F.
Barnett-Griness, ...
Andrulis, I L
Ozcelik, H.
Weerasooriya, N.
Gerdes, A-M
Thomassen, M.
Cruger, D G
Caligo, M A
Friedman, E.
Kaufman, B.
Laitman, Y.
Cohen, S.
Kontorovich, T.
Gershoni-Baruch, ...
Dagan, E.
Jernstrom, H.
Stenmark Askmalm ...
Arver, B.
Malmer, B.
Domchek, S M
Nathanson, K L
Brunet, J.
Cajal, T. Ramon ...
Yannoukakos, D.
Hamann, U.
Hogervorst, F B ...
Verhoef, S.
Gomez Garcia, E ...
Wijnen, J T
van den Ouweland ...
Easton, D F
Peock, S.
Cook, M.
Oliver, C T
Frost, D.
Luccarini, C.
Evans, D G
Lalloo, F.
Eeles, R.
Pichert, G.
Cook, J.
Hodgson, S.
Morrison, P J
Douglas, F.
Godwin, A K
Sinilnikova, O M
Barjhoux, L.
Stoppa-Lyonnet, ...
Moncoutier, V.
Giraud, S.
Cassini, C.
Olivier-Faivre, ...
Revillion, F.
Peyrat, J-P
Muller, D.
Fricker, J-P
Lynch, H T
John, E M
Buys, S.
Daly, M.
Hopper, J L
Terry, M B
Miron, A.
Yassin, Y.
Goldgar, D.
Singer, C F
Gschwantler-Kaul ...
Pfeiler, G.
Spiess, A-C
v. O. Hansen, Th ...
T. Johannsson, O ...
Kirchhoff, T.
Offit, K.
Kosarin, K.
Piedmonte, M.
C. Rodriguez, G.
Wakeley, K.
F. Boggess, J.
Basil, J.
E. Schwartz, P.
V. Blank, S.
E. Toland, A.
Montagna, M.
Casella, C.
N. Imyanitov, E.
Allavena, A.
K. Schmutzler, R ...
Versmold, B.
Engel, C.
Meindl, A.
Ditsch, N.
Arnold, N.
Niederacher, D.
Deissler, H.
Fiebig, B.
Varon-Mateeva, R ...
Schaefer, D.
G. Froster, U.
Caldes, T.
de la Hoya, M.
McGuffog, L.
C. Antoniou, A.
Nevanlinna, H.
Radice, P.
Benitez, J.
show less...
By the university
Swepub_uni:_t

Search outside SwePub

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view