Search: onr:"swepub:oai:DiVA.org:kth-211524" >
Synthesis of the ba...
Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants
-
- Hsieh, Yves S. Y. (author)
- University of Sydney, Australia
-
Wilkinson, Brendan L. (author)
-
O'Connell, Mitchell R. (author)
-
show more...
-
Mackay, Joel P. (author)
-
Matthews, Jacqueline M. (author)
-
Payne, Richard J (author)
-
show less...
-
(creator_code:org_t)
- 2012-03-28
- 2012
- English.
-
In: Organic Letters. - : American Chemical Society (ACS). - 1523-7060 .- 1523-7052. ; 14:7, s. 1910-3
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- The synthesis of sublancin 168, a unique S-glucosylated bacteriocin antibiotic, is described. The natural product and two S-glycosylated variants were successfully prepared via native chemical ligation followed by folding. The synthetic glycopeptides were shown to possess primarily an α-helical secondary structure by CD and NMR studies.
Subject headings
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmaceutiska vetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmaceutical Sciences (hsv//eng)
Keyword
- Native Chemical Ligation
- Linked Glycopeptides
- Peptide Ligation
- Aqueous-Solution
- Proteins
- Strategy
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database