Lack of control of hypertension in primary cardiovascular disease prevention in Europe: Results from the EURIKA study

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Borghi, ClaudioUniv Bologna, Italy (author)

Lack of control of hypertension in primary cardiovascular disease prevention in Europe : Results from the EURIKA study

Article/chapterEnglish2016

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Elsevier BV,2016
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LIBRIS-ID:oai:DiVA.org:lnu-54674
https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-54674URI
https://doi.org/10.1016/j.ijcard.2016.05.044DOI

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Language:English
Summary in:English

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Subject category:art swepub-publicationtype

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Background: The prevalence of and factors associated with uncontrolled hypertension and apparent resistant hypertension were assessed in the European Study on Cardiovascular Risk Prevention and Management in Usual Daily Practice (EURIKA; NCT00882336). Methods: EURIKA was a cross-sectional observational study including patients being treated for the primary prevention of cardiovascular disease in 12 European countries. Patients were assessed if they were being treated for hypertension (N = 5220). Blood pressure control was defined according to European guidelines, with sensitivity analysis taking account of patients' age and diabetes status. Associated factors were assessed using multivariate analysis. Results: In the primary analysis, a total of 2691 patients (51.6%) had uncontrolled hypertension. Factors significantly associated with an increased risk of having uncontrolled hypertension included female sex (odds ratio [OR]: 2.29; 95% confidence interval [CI]: 1.93-2.73), body mass index (BMI; OR per kg/m(2): 1.03; 95% CI: 1.01-1.04), and geographic location. A total of 749 patients (14.3%) had apparent resistant hypertension. Factors significantly associated with an increased risk of having apparent resistant hypertension included BMI (OR per kg/m(2): 1.06; 95% CI: 1.04-1.08), diabetes (OR: 1.28; 95% CI: 1.06-1.53), use of statins (OR: 1.36; 95% CI: 1.15-1.62), serum uric acid levels (OR: 1.16; 95% CI: 1.09-1.23), and geographic location. Similar results were seen in sensitivity analyses. Conclusions: Over 50% of patients treated for hypertension continued to have uncontrolled blood pressure and 14.3% had apparent resistant hypertension. Positive associations were seen with other cardiovascular risk factors. (C) 2016 Elsevier Ireland Ltd. All rights reserved.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Omvårdnad hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Nursing hsv//eng
Hypertension
Cardiovascular disease
Observational study
Primary prevention
Risk factor
Hälsovetenskap
Health and Caring Sciences

Added entries (persons, corporate bodies, meetings, titles ...)

Tubach, FlorenceHop Bichat Claude Bernard, France ; Univ Paris Diderot, France (author)
De Backer, GuyUniv Ghent, Belgium (author)
Dallongeville, JeanUniv Lille Nord France, France (author)
Guallar, EliseoJohns Hopkins Bloomberg Sch Publ Hlth, USA ; Natl Ctr Cardiovasc Res, Spain (author)
Medina, JesusAstraZeneca, Spain (author)
Perk, JoepLinnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV)(Swepub:lnu)jpejo (author)
Roy, CarineHop Bichat Claude Bernard, France (author)
Banegas, Jose R.Univ Autonoma Madrid IdiPaz, Spain ; CIBER Epidemiol & Publ Hlth CIBERESP, Spain (author)
Rodriguez-Artalejo, FernandoUniv Autonoma Madrid IdiPaz, Spain ; CIBER Epidemiol & Publ Hlth CIBERESP, Spain (author)
Halcox, Julian P.Swansea Univ, UK (author)
Univ Bologna, ItalyHop Bichat Claude Bernard, France ; Univ Paris Diderot, France (creator_code:org_t)

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In:International Journal of Cardiology: Elsevier BV218, s. 83-880167-52731874-1754

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By the author/editor: Borghi, Claudio; Tubach, Florence; De Backer, Guy; Dallongeville, J ...; Guallar, Eliseo; Medina, Jesus; show more...; Perk, Joep; Roy, Carine; Banegas, Jose R.; Rodriguez-Artale ...; Halcox, Julian P ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Nursing

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By the university: Linnaeus University

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