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Poor Self-Reported ...
Poor Self-Reported Sleep is Related to Regional Cortical Thinning in Aging but not Memory Decline-Results From the Lifebrain Consortium
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Fjell, Anders M. (author)
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Sørensen, Øystein (author)
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Amlien, Inge K. (author)
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Bartrés-Faz, David (author)
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Brandmaier, Andreas M. (author)
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Buchmann, Nikolaus (author)
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Demuth, Ilja (author)
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Drevon, Christian A. (author)
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Düzel, Sandra (author)
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Ebmeier, Klaus P. (author)
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Ghisletta, Paolo (author)
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Idland, Ane-Victoria (author)
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Kietzmann, Tim C. (author)
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Kievit, Rogier A. (author)
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Kühn, Simone (author)
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Lindenberger, Ulman (author)
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Magnussen, Fredrik (author)
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Macià, Didac (author)
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Mowinckel, Athanasia M. (author)
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- Nyberg, Lars, 1966- (author)
- Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Institutionen för strålningsvetenskaper
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Sexton, Claire E. (author)
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Solé-Padullés, Cristina (author)
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- Pudas, Sara, Docent, 1983- (author)
- Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Institutionen för strålningsvetenskaper
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Roe, James M. (author)
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Sederevicius, Donatas (author)
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Suri, Sana (author)
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Vidal-Piñeiro, Didac (author)
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Wagner, Gerd (author)
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Watne, Leiv Otto (author)
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Westerhausen, René (author)
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Zsoldos, Enikő (author)
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Walhovd, Kristine B. (author)
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(creator_code:org_t)
- 2020-11-25
- 2021
- English.
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In: Cerebral Cortex. - : Oxford University Press. - 1047-3211 .- 1460-2199. ; 31:4, s. 1953-1969
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- We examined whether sleep quality and quantity are associated with cortical and memory changes in cognitively healthy participants across the adult lifespan. Associations between self-reported sleep parameters (Pittsburgh Sleep Quality Index, PSQI) and longitudinal cortical change were tested using five samples from the Lifebrain consortium (n = 2205, 4363 MRIs, 18-92 years). In additional analyses, we tested coherence with cell-specific gene expression maps from the Allen Human Brain Atlas, and relations to changes in memory performance. "PSQI # 1 Subjective sleep quality" and "PSQI #5 Sleep disturbances" were related to thinning of the right lateral temporal cortex, with lower quality and more disturbances being associated with faster thinning. The association with "PSQI #5 Sleep disturbances" emerged after 60 years, especially in regions with high expression of genes related to oligodendrocytes and S1 pyramidal neurons. None of the sleep scales were related to a longitudinal change in episodic memory function, suggesting that sleep-related cortical changes were independent of cognitive decline. The relationship to cortical brain change suggests that self-reported sleep parameters are relevant in lifespan studies, but small effect sizes indicate that self-reported sleep is not a good biomarker of general cortical degeneration in healthy older adults.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Övrig annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Other Medical and Health Sciences not elsewhere specified (hsv//eng)
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Keyword
- aging
- atrophy
- cortex
- sleep
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Fjell, Anders M.
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Sørensen, Øystei ...
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Amlien, Inge K.
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Bartrés-Faz, Dav ...
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Brandmaier, Andr ...
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Buchmann, Nikola ...
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show more...
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Demuth, Ilja
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Drevon, Christia ...
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Düzel, Sandra
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Ebmeier, Klaus P ...
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Ghisletta, Paolo
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Idland, Ane-Vict ...
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Kietzmann, Tim C ...
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Kievit, Rogier A ...
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Kühn, Simone
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Lindenberger, Ul ...
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Magnussen, Fredr ...
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Macià, Didac
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Mowinckel, Athan ...
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Nyberg, Lars, 19 ...
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Sexton, Claire E ...
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Solé-Padullés, C ...
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Pudas, Sara, Doc ...
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Roe, James M.
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Sederevicius, Do ...
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Suri, Sana
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Vidal-Piñeiro, D ...
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Wagner, Gerd
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Watne, Leiv Otto
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Westerhausen, Re ...
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Zsoldos, Enikő
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Walhovd, Kristin ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Neurosciences
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Other Medical an ...
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and Other Medical an ...
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Psychology
- Articles in the publication
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Cerebral Cortex
- By the university
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Umeå University