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  • Arakelian, ErebouniUppsala universitet,Sjuksköterskeutbildningar,Uppsala universitet, Sjuksköterskeutbildningar (author)

Pulmonary influences on early post-operative recovery in patients after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy treatment : a retrospective study

  • Article/chapterEnglish2012

Publisher, publication year, extent ...

  • 2012-11-27
  • Springer Science and Business Media LLC,2012
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-193642
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-193642URI
  • https://doi.org/10.1186/1477-7819-10-258DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-41671URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

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  • Background: The combination of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a curative treatment option for peritoneal carcinomatosis (PC). There have been few studies on the pulmonary adverse events (AEs) affecting patient recovery after this treatment, thus this study investigated these factors. Methods: Between January 2005 and December 2006, clinical data on all pulmonary AEs and the recovery progress were reviewed for 76 patients with after CRS and HIPEC. Patients with pulmonary interventions (thoracocenthesis and chest tubes) were compared with the non-intervention patients. Two senior radiologists, blinded to the post-operative clinical course, separately graded the occurrence of pulmonary AEs. Results: Of the 76 patients, 6 had needed thoracocentesis and another 6 needed chest tubes. There were no differences in post-operative recovery between the intervention and non-intervention groups. The total number of days on mechanical ventilation, the length of stay in the intensive care unit, total length of hospital stay, tumor burden, and an American Society of Anesthesiologists (ASA) grade of greater than 2 were correlated with the occurrence of atelectasis and pleural effusion. Extensive atelectasis (grade 3 or higher) was seen in six patients, major pleural effusion (grade 3) in seven patients, and signs of heart failure (grade 1-2) in nine patients. Conclusions: Clinical and radiological post-operative pulmonary AEs are common after CRS and HIPEC. However, most of the pulmonary AEs did not affect post-operative recovery.

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  • Torkzad, Michael R.Uppsala universitet,Enheten för radiologi,Uppsala universitet, Enheten för radiologi(Swepub:uu)micto583 (author)
  • Bergman, AntoninaUppsala universitet,Enheten för radiologi,Uppsala universitet, Enheten för radiologi(Swepub:uu)abe03125 (author)
  • Rubertsson, StenUppsala universitet,Anestesiologi och intensivvård,Uppsala universitet, Anestesiologi och intensivvård(Swepub:uu)stenrube (author)
  • Mahteme, HaileUppsala universitet,Kolorektalkirurgi,Uppsala universitet, Kolorektalkirurgi(Swepub:uu)hailmaht (author)
  • Uppsala universitetSjuksköterskeutbildningar (creator_code:org_t)

Related titles

  • In:World Journal of Surgical Oncology: Springer Science and Business Media LLC10, s. 258-1477-7819

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