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U-CAN :
U-CAN : a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
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- Glimelius, Bengt (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Melin, Beatrice (author)
- Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå
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- Enblad, Gunilla (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Alafuzoff, Irina (author)
- Uppsala universitet,Klinisk och experimentell patologi,Irina Alafuzoff
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- Beskow, Anna H. (author)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR)
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- Ahlström, Håkan (author)
- Uppsala universitet,Radiologi
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- Bill-Axelson, Anna (author)
- Uppsala universitet,Urologkirurgi
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- Birgisson, Helgi (author)
- Uppsala universitet,Gastrointestinalkirurgi
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- Björ, Ove (author)
- Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå
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- Edqvist, Per-Henrik D (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Hansson, Tony (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Helleday, Thomas (author)
- Karolinska Institutet
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- Hellman, Per (author)
- Uppsala universitet,Endokrinkirurgi
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- Henriksson, Kerstin (author)
- Uppsala universitet,Institutionen för immunologi, genetik och patologi
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- Hesselager, Göran (author)
- Uppsala universitet,Neurokirurgi
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- Hultdin, Magnus (author)
- Umeå universitet,Patologi,Umeå Univ, Dept Med Biosci, Pathol, Umeå
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- Häggman, Michael (author)
- Uppsala universitet,Urologkirurgi
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- Höglund, Martin (author)
- Uppsala universitet,Hematologi
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- Jonsson, Håkan (author)
- Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå
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- Larsson, Chatarina, 1979- (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Lindman, Henrik (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Ljuslinder, Ingrid (author)
- Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå
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- Mindus, Stephanie (author)
- Akad Sjukhuset, Lung & Allergy Clin, Uppsala
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- Nygren, Peter (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Ponten, Fredrik (author)
- Uppsala universitet,Klinisk och experimentell patologi,Fredrik Pontén
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- Riklund, Katrine (author)
- Umeå universitet,Diagnostisk radiologi,Umeå Univ, Dept Radiat Sci, Umeå
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- Rosenquist, Richard (author)
- Karolinska Institutet,Uppsala universitet,Experimentell och klinisk onkologi
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- Sandin, Fredrik (author)
- Uppsala Univ Hosp, RCC Uppsala Örebro, Uppsala
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- Schwenk, Jochen M. (author)
- KTH,Proteinvetenskap,KTH Royal Inst Technol, Sch Biotechnol, Affin Prote, SciLifeLab, Solna
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- Stenling, Roger (author)
- Umeå universitet,Patologi,Umeå Univ, Dept Med Biosci, Pathol, Umeå
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- Stålberg, Karin (author)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa
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- Stålberg, Peter (author)
- Uppsala universitet,Endokrinkirurgi
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- Sundström, Christer (author)
- Uppsala universitet,Klinisk och experimentell patologi,Rose-Marie Amini
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- Thellenberg Karlsson, Camilla (author)
- Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå
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- Westermark, Bengt (author)
- Uppsala universitet,Neuroonkologi
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- Bergh, Anders (author)
- Umeå universitet,Patologi,Umeå Univ, Dept Med Biosci, Pathol, Umeå
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- Claesson-Welsh, Lena (author)
- Uppsala universitet,Vaskulärbiologi
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- Palmqvist, Richard (author)
- Umeå universitet,Patologi,Umeå Univ, Dept Med Biosci, Pathol, Umeå
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- Sjöblom, Tobias (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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(creator_code:org_t)
- Taylor & Francis, 2018
- 2018
- English.
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In: Acta Oncologica. - : Taylor & Francis. - 0284-186X .- 1651-226X. ; 57:2, s. 187-194
- Related links:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Subject headings
Close
- Background: Progress in cancer biomarker discovery is dependent on access to high-quality biological materials and high-resolution clinical data from the same cases. To overcome current limitations, a systematic prospective longitudinal sampling of multidisciplinary clinical data, blood and tissue from cancer patients was therefore initiated in 2010 by Uppsala and Umeå Universities and involving their corresponding University Hospitals, which are referral centers for one third of the Swedish population.Material and Methods: Patients with cancer of selected types who are treated at one of the participating hospitals are eligible for inclusion. The healthcare-integrated sampling scheme encompasses clinical data, questionnaires, blood, fresh frozen and formalin-fixed paraffin-embedded tissue specimens, diagnostic slides and radiology bioimaging data.Results: In this ongoing effort, 12,265 patients with brain tumors, breast cancers, colorectal cancers, gynecological cancers, hematological malignancies, lung cancers, neuroendocrine tumors or prostate cancers have been included until the end of 2016. From the 6914 patients included during the first five years, 98% were sampled for blood at diagnosis, 83% had paraffin-embedded and 58% had fresh frozen tissues collected. For Uppsala County, 55% of all cancer patients were included in the cohort.Conclusions: Close collaboration between participating hospitals and universities enabled prospective, longitudinal biobanking of blood and tissues and collection of multidisciplinary clinical data from cancer patients in the U-CAN cohort. Here, we summarize the first five years of operations, present U-CAN as a highly valuable cohort that will contribute to enhanced cancer research and describe the procedures to access samples and data.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
Keyword
- Patologi
- Pathology
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Glimelius, Bengt
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Melin, Beatrice
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Enblad, Gunilla
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Alafuzoff, Irina
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Beskow, Anna H.
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Ahlström, Håkan
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show more...
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Bill-Axelson, An ...
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Birgisson, Helgi
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Björ, Ove
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Edqvist, Per-Hen ...
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Hansson, Tony
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Helleday, Thomas
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Hellman, Per
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Henriksson, Kers ...
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Hesselager, Göra ...
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Hultdin, Magnus
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Häggman, Michael
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Höglund, Martin
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Jonsson, Håkan
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Larsson, Chatari ...
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Lindman, Henrik
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Ljuslinder, Ingr ...
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Mindus, Stephani ...
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Nygren, Peter
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Ponten, Fredrik
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Riklund, Katrine
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Rosenquist, Rich ...
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Sandin, Fredrik
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Schwenk, Jochen ...
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Stenling, Roger
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Stålberg, Karin
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Stålberg, Peter
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Sundström, Chris ...
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Thellenberg Karl ...
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Westermark, Beng ...
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Bergh, Anders
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Claesson-Welsh, ...
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Palmqvist, Richa ...
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Sjöblom, Tobias
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Urology and Neph ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Clinical Laborat ...
- Articles in the publication
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Acta Oncologica
- By the university
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Uppsala University
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Umeå University
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Royal Institute of Technology
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Karolinska Institutet