Search: onr:"swepub:oai:lup.lub.lu.se:70dadeef-14bb-4a1c-91fd-e097aa36b000" >
Snus (Swedish smoke...
Snus (Swedish smokeless tobacco) use and risk of stroke: pooled analyses of incidence and survival
-
- Jansson, Jan-Håkan (author)
- Umeå universitet,Medicin
-
- Galanti, M. R. (author)
- Karolinska Institutet
-
Hergens, M. -P. (author)
-
show more...
-
Fredlund, P. (author)
-
- Ahlbom, A. (author)
- Karolinska Institutet
-
- Alfredsson, L. (author)
- Karolinska Institutet
-
- Bellocco, R. (author)
- Karolinska Institutet
-
- Engström, Gunnar (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups
-
- Eriksson, Marie (author)
- Umeå universitet,Statistik
-
- Hallqvist, Johan (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
-
- Hedblad, Bo (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups
-
Jansson, J. -H. (author)
-
- Pedersen, N. L. (author)
- Karolinska Institutet
-
- Trolle Lagerros, Y. (author)
- Karolinska Institutet
-
- Östergren, Per-Olof (author)
- Lund University,Lunds universitet,Socialmedicin och global hälsa,Forskargrupper vid Lunds universitet,Social Medicine and Global Health,Lund University Research Groups
-
- Magnusson, C. (author)
- Karolinska Institutet
-
show less...
-
(creator_code:org_t)
- 2014-03-29
- 2014
- English.
-
In: Journal of Internal Medicine. - : Wiley. - 1365-2796 .- 0954-6820. ; 276:1, s. 87-95
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://onlinelibrar...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
http://kipublication...
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- Background. Snus is a moist smokeless tobacco product with high nicotine content. Its use has a short-term effect on the cardiovascular system, but the relationship between snus use and stroke is unclear. Objective. The aim of this study was to assess the associations between use of snus and incidence of and survival after stroke, both overall and according to subtypes. Methods. Pooled analyses of eight Swedish prospective cohort studies were conducted, including 130 485 men who never smoked. We estimated hazard ratios (HRs) with 95% confidence intervals (CIs) of incidence and death after diagnosis using Cox proportional hazard regression models and case fatality and survival using logistic regression and Kaplan-Meier methods, respectively. Results. No associations were observed between the use of snus and the risk of overall stroke (HR 1.04, 95% CI 0.92-1.17) or of any of the stroke subtypes. The odds ratio (OR) of 28-day case fatality was 1.42 (95% CI 0.99-2.04) amongst users of snus who had experienced a stroke, and the HR of death during the follow-up period was 1.32 (95% CI 1.08-1.61). Conclusion. Use of snus was not associated with the risk of stroke. Hence, nicotine is unlikely to contribute importantly to the pathophysiology of stroke. However, case fatality was increased in snus users, compared with nonusers, but further studies are needed to determine any possible causal mechanisms.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- smokeless tobacco
- snus
- stroke
- smokeless tobacco
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
-
Jansson, Jan-Håk ...
-
Galanti, M. R.
-
Hergens, M. -P.
-
Fredlund, P.
-
Ahlbom, A.
-
Alfredsson, L.
-
show more...
-
Bellocco, R.
-
Engström, Gunnar
-
Eriksson, Marie
-
Hallqvist, Johan
-
Hedblad, Bo
-
Jansson, J. -H.
-
Pedersen, N. L.
-
Trolle Lagerros, ...
-
Östergren, Per-O ...
-
Magnusson, C.
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Occupational Hea ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cardiac and Card ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Public Health Gl ...
- Articles in the publication
-
Journal of Inter ...
- By the university
-
Lund University
-
Umeå University
-
Karolinska Institutet
-
Uppsala University