Search: onr:"swepub:oai:prod.swepub.kib.ki.se:129776136" >
Common genetic vari...
Common genetic variants associated with cognitive performance identified using the proxy-phenotype method
-
- Rietveld, CA (author)
- Erasmus University (NL)
-
- Esko, T (author)
- University of Tartu
-
- Davies, G (author)
- Bristol University (GB),University of Edinburgh
-
show more...
-
- Pers, TH (author)
- Erasmus University (NL),Boston Children's Hospital
-
- Turley, P (author)
- Massachusetts General Hospital (US)
-
- Benyamin, B (author)
- Cornell University (US),University of Queensland (AU)
-
- Chabris, CF (author)
- Union College (US),Erasmus Medical Center
-
- Emilsson, V (author)
- University of Iceland,University of Queensland (AU)
-
- Johnson, AD (author)
- National Heart Institute
-
- Lee, JJ (author)
- University of Minnesota Twin Cities (US),Erasmus Medical Center
-
- de Leeuw, C (author)
- University of Amsterdam (NL)
-
- Marioni, RE (author)
- University of Queensland (AU)
-
- Medland, SE (author)
- Queensland Institute of Medical Research
-
- Miller, MB (author)
- University of Minnesota Twin Cities (US)
-
- Rostapshova, O (author)
- Harvard University (US)
-
van der Lee, SJ (author)
-
Vinkhuyzen, AAE (author)
-
- Amin, N (author)
- Erasmus Medical Center
-
- Conley, D (author)
- Massachusetts Institute of Technology (US),University of Edinburgh
-
- Derringer, J (author)
- University of Illinois (US)
-
- van Duijn, CM (author)
- Leiden University
-
- Fehrmann, R (author)
- University of Groningen (NL)
-
- Franke, L (author)
- University of Groningen (NL)
-
- Glaeser, EL (author)
- Harvard University (US)
-
- Hansell, NK (author)
- QIMR Berghofer Medical Research Institute
-
- Hayward, C (author)
- University of Edinburgh
-
- Iacono, WG (author)
- University of Minnesota Twin Cities (US)
-
- Ibrahim-Verbaas, C (author)
- Harvard University (US)
-
- Jaddoe, V (author)
- Erasmus Medical Center
-
- Karjalainen, J (author)
- University of Groningen (NL)
-
- Laibson, D (author)
- Harvard University (US)
-
- Lichtenstein, P (author)
- Karolinska Institutet,Karolinska Institutet (SE)
-
- Liewald, DC (author)
- Massachusetts Institute of Technology (US)
-
- Magnusson, PKE (author)
- Karolinska Institutet,Karolinska Institutet (SE)
-
- Martin, NG (author)
- Queensland Institute of Medical Research
-
- Mcgue, M (author)
- University of Edinburgh,University of Queensland (AU)
-
- McMahon, G (author)
- Bristol University (GB)
-
- Pedersen, NL (author)
- Karolinska Institutet
-
- Pinker, S (author)
- University of Cambridge
-
- Porteous, DJ (author)
- University of Edinburgh
-
- Posthuma, D (author)
- VU University (NL)
-
- Rivadeneira, F (author)
- Erasmus University (NL)
-
- Smith, BH (author)
- University of Dundee
-
- Johannesson, Magnus (author)
- Stockholm School of Economics,Handelshögskolan i Stockholm
-
Tiemeier, H (author)
-
- Timpson, NJ (author)
- Bristol University (GB)
-
- Trzaskowski, M (author)
- King's College London (GB)
-
- Uitterlinden, AG (author)
- Erasmus University (NL)
-
Verhulst, FC (author)
-
- Ward, ME (author)
- Bristol University (GB)
-
- Wright, MJ (author)
- QIMR Berghofer Medical Research Institute
-
Smith, GD (author)
-
- Deary, IJ (author)
- University of Edinburgh
-
Johannesson, M (author)
-
- Plomin, R (author)
- King's College London (GB)
-
Visscher, PM (author)
-
Benjamin, DJ (author)
-
Cesarini, D (author)
-
- Koellinger, PD (author)
- Erasmus School of Economics (NL)
-
show less...
-
(creator_code:org_t)
- 2014-09-08
- 2014
- English.
-
In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 1091-6490 .- 0027-8424. ; 111:38, s. 13790-13794
- Related links:
-
https://www.pnas.org...
-
show more...
-
http://kipublication...
-
https://doi.org/10.1...
-
https://research.hhs...
-
show less...
Abstract
Subject headings
Close
- We identify several common genetic variants associated with cognitive performance using a two-stage approach: we conduct a genome-wide association study of educational attainment to generate a set of candidates, and then we estimate the association of these variants with cognitive performance. In older Americans, we find that these variants are jointly associated with cognitive health. Bioinformatics analyses implicate a set of genes that is associated with a particular neurotransmitter pathway involved in synaptic plasticity, the main cellular mechanism for learning and memory. In addition to the substantive contribution, this work also serves to show a proxy-phenotype approach to discovering common genetic variants that is likely to be useful for many phenotypes of interest to social scientists (such as personality traits).
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Rietveld, CA
-
Esko, T
-
Davies, G
-
Pers, TH
-
Turley, P
-
Benyamin, B
-
show more...
-
Chabris, CF
-
Emilsson, V
-
Johnson, AD
-
Lee, JJ
-
de Leeuw, C
-
Marioni, RE
-
Medland, SE
-
Miller, MB
-
Rostapshova, O
-
van der Lee, SJ
-
Vinkhuyzen, AAE
-
Amin, N
-
Conley, D
-
Derringer, J
-
van Duijn, CM
-
Fehrmann, R
-
Franke, L
-
Glaeser, EL
-
Hansell, NK
-
Hayward, C
-
Iacono, WG
-
Ibrahim-Verbaas, ...
-
Jaddoe, V
-
Karjalainen, J
-
Laibson, D
-
Lichtenstein, P
-
Liewald, DC
-
Magnusson, PKE
-
Martin, NG
-
Mcgue, M
-
McMahon, G
-
Pedersen, NL
-
Pinker, S
-
Porteous, DJ
-
Posthuma, D
-
Rivadeneira, F
-
Smith, BH
-
Johannesson, Mag ...
-
Tiemeier, H
-
Timpson, NJ
-
Trzaskowski, M
-
Uitterlinden, AG
-
Verhulst, FC
-
Ward, ME
-
Wright, MJ
-
Smith, GD
-
Deary, IJ
-
Johannesson, M
-
Plomin, R
-
Visscher, PM
-
Benjamin, DJ
-
Cesarini, D
-
Koellinger, PD
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Neurosciences
- Articles in the publication
-
Proceedings of t ...
-
Proceedings of t ...
- By the university
-
Karolinska Institutet
-
Stockholm School of Economics