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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 07458naa a22020173a 4500 | |
| 001 | 22116373 | |
| 003 | SE-LIBR | |
| 005 | 20171213163418.0 | |
| 007 | cr|||||||||||| | |
| 008 | 171213s2009 sw |||| o |||| ||eng c | |
| 024 | 7 | a http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-529122 uri |
| 024 | 7 | a urn:nbn:se:liu:diva-529122 urn |
| 024 | 7 | a 10.1038/sj.bjc.66054162 doi |
| 040 | a S | |
| 041 | 0 | a eng |
| 042 | 9 EPLK | |
| 100 | 1 | a Osorio, A.4 aut |
| 245 | 1 0 | a Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)h [Elektronisk resurs] |
| 260 | c 2009 | |
| 500 | a Published | |
| 506 | 0 | a gratis |
| 520 | a BACKGROUND: In this study we aimed to evaluate the role of a SNP in intron I of the ERCC4 gene (rs744154), previously reported to be associated with a reduced risk of breast cancer in the general population, as a breast cancer risk modifier in BRCA1 and BRCA2 mutation carriers. METHODS: We have genotyped rs744154 in 9408 BRCA1 and 5632 BRCA2 mutation carriers from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) and assessed its association with breast cancer risk using a retrospective weighted cohort approach. RESULTS: We found no evidence of association with breast cancer risk for BRCA1 (per-allele HR: 0.98, 95% CI: 0.93-1.04, P = 0.5) or BRCA2 (per-allele HR: 0.97, 95% CI: 0.89-1.06, P = 0.5) mutation carriers. CONCLUSION: This SNP is not a significant modifier of breast cancer risk for mutation carriers, though weak associations cannot be ruled out. | |
| 650 | 7 | a Medical and Health Sciences2 hsv |
| 650 | 7 | a Medicin och hälsovetenskap2 hsv |
| 650 | 7 | a MEDICINE2 svep |
| 650 | 7 | a MEDICIN2 svep |
| 653 | 0 | a BRCA1; BRCA2; ERCC4; breast cancer |
| 700 | 1 | a Milne, R L4 aut |
| 700 | 1 | a Pita, G.4 aut |
| 700 | 1 | a Peterlongo, P.4 aut |
| 700 | 1 | a Heikkinen, T.4 aut |
| 700 | 1 | a Simard, J.4 aut |
| 700 | 1 | a Chenevix-Trench, G.4 aut |
| 700 | 1 | a Spurdle, A B4 aut |
| 700 | 1 | a Beesley, J.4 aut |
| 700 | 1 | a Chen, X.4 aut |
| 700 | 1 | a Healey, S.4 aut |
| 700 | 1 | a Neuhausen, S L4 aut |
| 700 | 1 | a Ding, Y C4 aut |
| 700 | 1 | a Couch, F J4 aut |
| 700 | 1 | a Wang, X.4 aut |
| 700 | 1 | a Lindor, N.4 aut |
| 700 | 1 | a Manoukian, S.4 aut |
| 700 | 1 | a Barile, M.4 aut |
| 700 | 1 | a Viel, A.4 aut |
| 700 | 1 | a Tizzoni, L.4 aut |
| 700 | 1 | a Szabo, C I4 aut |
| 700 | 1 | a Foretova, L.4 aut |
| 700 | 1 | a Zikan, M.4 aut |
| 700 | 1 | a Claes, K.4 aut |
| 700 | 1 | a Greene, M H4 aut |
| 700 | 1 | a Mai, P.4 aut |
| 700 | 1 | a Rennert, G.4 aut |
| 700 | 1 | a Lejbkowicz, F.4 aut |
| 700 | 1 | a Barnett-Griness, O.4 aut |
| 700 | 1 | a Andrulis, I L4 aut |
| 700 | 1 | a Ozcelik, H.4 aut |
| 700 | 1 | a Weerasooriya, N.4 aut |
| 700 | 1 | a Gerdes, A-M4 aut |
| 700 | 1 | a Thomassen, M.4 aut |
| 700 | 1 | a Cruger, D G4 aut |
| 700 | 1 | a Caligo, M A4 aut |
| 700 | 1 | a Friedman, E.4 aut |
| 700 | 1 | a Kaufman, B.4 aut |
| 700 | 1 | a Laitman, Y.4 aut |
| 700 | 1 | a Cohen, S.4 aut0 46554 |
| 700 | 1 | a Kontorovich, T.4 aut |
| 700 | 1 | a Gershoni-Baruch, R.4 aut |
| 700 | 1 | a Dagan, E.4 aut |
| 700 | 1 | a Jernstrom, H.4 aut |
| 700 | 1 | a Stenmark Askmalm, Marie4 aut |
| 700 | 1 | a Arver, B.4 aut |
| 700 | 1 | a Malmer, B.4 aut |
| 700 | 1 | a Domchek, S M4 aut |
| 700 | 1 | a Nathanson, K L4 aut |
| 700 | 1 | a Brunet, J.4 aut |
| 700 | 1 | a Cajal, T. Ramon y4 aut |
| 700 | 1 | a Yannoukakos, D.4 aut |
| 700 | 1 | a Hamann, U.4 aut |
| 700 | 1 | a Hogervorst, F B L4 aut |
| 700 | 1 | a Verhoef, S.4 aut |
| 700 | 1 | a Gomez Garcia, E B4 aut |
| 700 | 1 | a Wijnen, J T4 aut |
| 700 | 1 | a van den Ouweland, A.4 aut |
| 700 | 1 | a Easton, D F4 aut |
| 700 | 1 | a Peock, S.4 aut |
| 700 | 1 | a Cook, M.4 aut |
| 700 | 1 | a Oliver, C T4 aut |
| 700 | 1 | a Frost, D.4 aut |
| 700 | 1 | a Luccarini, C.4 aut |
| 700 | 1 | a Evans, D G4 aut |
| 700 | 1 | a Lalloo, F.4 aut |
| 700 | 1 | a Eeles, R.4 aut |
| 700 | 1 | a Pichert, G.4 aut |
| 700 | 1 | a Cook, J.4 aut |
| 700 | 1 | a Hodgson, S.4 aut |
| 700 | 1 | a Morrison, P J4 aut |
| 700 | 1 | a Douglas, F.4 aut |
| 700 | 1 | a Godwin, A K4 aut |
| 700 | 1 | a Sinilnikova, O M4 aut |
| 700 | 1 | a Barjhoux, L.4 aut |
| 700 | 1 | a Stoppa-Lyonnet, D.4 aut |
| 700 | 1 | a Moncoutier, V.4 aut |
| 700 | 1 | a Giraud, S.4 aut |
| 700 | 1 | a Cassini, C.4 aut |
| 700 | 1 | a Olivier-Faivre, L.4 aut |
| 700 | 1 | a Revillion, F.4 aut |
| 700 | 1 | a Peyrat, J-P4 aut |
| 700 | 1 | a Muller, D.4 aut |
| 700 | 1 | a Fricker, J-P4 aut |
| 700 | 1 | a Lynch, H T4 aut |
| 700 | 1 | a John, E M4 aut |
| 700 | 1 | a Buys, S.4 aut |
| 700 | 1 | a Daly, M.4 aut |
| 700 | 1 | a Hopper, J L4 aut |
| 700 | 1 | a Terry, M B4 aut |
| 700 | 1 | a Miron, A.4 aut |
| 700 | 1 | a Yassin, Y.4 aut |
| 700 | 1 | a Goldgar, D.4 aut |
| 700 | 1 | a Singer, C F4 aut |
| 700 | 1 | a Gschwantler-Kaulich, D.4 aut |
| 700 | 1 | a Pfeiler, G.4 aut |
| 700 | 1 | a Spiess, A-C4 aut |
| 700 | 1 | a v. O. Hansen, Thomas4 aut |
| 700 | 1 | a T. Johannsson, O.4 aut |
| 700 | 1 | a Kirchhoff, T.4 aut |
| 700 | 1 | a Offit, K.4 aut |
| 700 | 1 | a Kosarin, K.4 aut |
| 700 | 1 | a Piedmonte, M.4 aut |
| 700 | 1 | a C. Rodriguez, G.4 aut |
| 700 | 1 | a Wakeley, K.4 aut |
| 700 | 1 | a F. Boggess, J.4 aut |
| 700 | 1 | a Basil, J.4 aut |
| 700 | 1 | a E. Schwartz, P.4 aut |
| 700 | 1 | a V. Blank, S.4 aut |
| 700 | 1 | a E. Toland, A.4 aut |
| 700 | 1 | a Montagna, M.4 aut |
| 700 | 1 | a Casella, C.4 aut |
| 700 | 1 | a N. Imyanitov, E.4 aut |
| 700 | 1 | a Allavena, A.4 aut |
| 700 | 1 | a K. Schmutzler, R.4 aut |
| 700 | 1 | a Versmold, B.4 aut |
| 700 | 1 | a Engel, C.4 aut |
| 700 | 1 | a Meindl, A.4 aut |
| 700 | 1 | a Ditsch, N.4 aut |
| 700 | 1 | a Arnold, N.4 aut |
| 700 | 1 | a Niederacher, D.4 aut |
| 700 | 1 | a Deissler, H.4 aut |
| 700 | 1 | a Fiebig, B.4 aut |
| 700 | 1 | a Varon-Mateeva, R.4 aut |
| 700 | 1 | a Schaefer, D.4 aut |
| 700 | 1 | a G. Froster, U.4 aut |
| 700 | 1 | a Caldes, T.4 aut |
| 700 | 1 | a de la Hoya, M.4 aut |
| 700 | 1 | a McGuffog, L.4 aut |
| 700 | 1 | a C. Antoniou, A.4 aut |
| 700 | 1 | a Nevanlinna, H.4 aut |
| 700 | 1 | a Radice, P.4 aut |
| 700 | 1 | a Benitez, J.4 aut |
| 710 | 1 2 | a Linköpings universitetb Institutionen för klinisk och experimentell medicin4 pbl0 347333 |
| 710 | 1 2 | a Linköpings universitetb Hälsouniversitetet4 pbl |
| 710 | 1 2 | a Östergötlands Läns Landstingb Diagnostikcentrum4 pbl |
| 772 | 1 8 | i channel recordw 18478042 |
| 773 | 0 8 | i Värdpublikationt British Journal of Cancerg 101:12, 2048-2054x 0007-0920 |
| 856 | 4 0 | u http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-52912 |
| 856 | 4 0 | u http://dx.doi.org/10.1038/sj.bjc.6605416 |
| 856 | 4 0 | u http://liu.diva-portal.org/smash/get/diva2:285720/FULLTEXT01 |
| 900 | 1 s | 6 700a Kohen, S.u Cohen, S. |
| 910 | 2 s | 6 710a IKEu Linköpings universitet.b Institutionen för klinisk och experimentell medicin |
| 910 | 2 s | 6 710a Linköping University.b Department of Clinical and Experimental Medicineu Linköpings universitet.b Institutionen för klinisk och experimentell medicin |
| 910 | 2 s | 6 710a Linköping University.b Faculty of Health Sciences.b Department of Clinical and Experimental Medicineu Linköpings universitet.b Institutionen för klinisk och experimentell medicin |
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