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Sökning: WFRF:(Westerlund M) > Job strain as a ris...

  • Kivimäki, M.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)

Job strain as a risk factor for coronary heart disease : A collaborative meta-analysis of individual participant data

  • Artikel/kapitelEngelska2012

Förlag, utgivningsår, omfång ...

  • Elsevier,2012
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:miun-17376
  • https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-17376URI
  • https://doi.org/10.1016/S0140-6736(12)60994-5DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-60552URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-80461URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:125476398URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-185493URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-19425URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • CODEN: LANCA
  • Background Published work assessing psychosocial stress (job strain) as a risk factor for coronary heart disease is inconsistent and subject to publication bias and reverse causation bias. We analysed the relation between job strain and coronary heart disease with a meta-analysis of published and unpublished studies. Methods We used individual records from 13 European cohort studies (1985-2006) of men and women without coronary heart disease who were employed at time of baseline assessment. We measured job strain with questions from validated job-content and demand-control questionnaires. We extracted data in two stages such that acquisition and harmonisation of job strain measure and covariables occurred before linkage to records for coronary heart disease. We defined incident coronary heart disease as the first non-fatal myocardial infarction or coronary death. Findings 30 214 (15%) of 197 473 participants reported job strain. In 1•49 million person-years at risk (mean follow-up 7•5 years [SD 1•7]), we recorded 2358 events of incident coronary heart disease. After adjustment for sex and age, the hazard ratio for job strain versus no job strain was 1•23 (95% CI 1•10-1•37). This effect estimate was higher in published (1•43, 1•15-1•77) than unpublished (1•16, 1•02-1•32) studies. Hazard ratios were likewise raised in analyses addressing reverse causality by exclusion of events of coronary heart disease that occurred in the first 3 years (1•31, 1•15-1•48) and 5 years (1•30, 1•13-1•50) of follow-up. We noted an association between job strain and coronary heart disease for sex, age groups, socioeconomic strata, and region, and after adjustments for socioeconomic status, and lifestyle and conventional risk factors. The population attributable risk for job strain was 3•4%. Interpretation Our findings suggest that prevention of workplace stress might decrease disease incidence; however, this strategy would have a much smaller effect than would tackling of standard risk factors, such as smoking. Funding Finnish Work Environment Fund, the Academy of Finland, the Swedish Research Council for Working Life and Social Research, the German Social Accident Insurance, the Danish National Research Centre for the Working Environment, the BUPA Foundation, the Ministry of Social Affairs and Employment, the Medical Research Council, the Wellcome Trust, and the US National Institutes of Health.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Theorell, TöresKarolinska Institutet,Stockholms universitet,Stressforskningsinstitutet(Swepub:su)ttheo (författare)
  • Batty, G. D.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)
  • Fransson, Eleonor,1971-Jönköping University,Stockholms universitet,Stressforskningsinstitutet,Karolinska Institutet, Sweden; Jönköping University, Sweden,HHJ, Avdelningen för naturvetenskap och biomedicin,HHJ. ADULT,HHJ. Åldrande - livsvillkor och hälsa(Swepub:hj)FrEl (författare)
  • Heikkilä, K.Finnish Institute of Occupational Health, Helsinki, Finland (författare)
  • Alfredsson, L.Karolinska Institutet (författare)
  • Bjorner, J. B.National Research Centre for the Working Environment, Copenhagen, Denmark (författare)
  • Borritz, M.Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Copenhagen, Denmark (författare)
  • Burr, H.Federal Institute for Occupational Safety and Health (BAuA), Berlin, Germany (författare)
  • Casini, A.School of Public Health, Université Libre de Bruxelles, Brussels, Belgium (författare)
  • Clays, E.Department of Public Health, Ghent University, Ghent, Belgium (författare)
  • De Bacquer, D.Department of Public Health, Ghent University, Ghent, Belgium (författare)
  • Dragano, N.Department of Medical Sociology, University of Düsseldorf, Düsseldorf, Germany (författare)
  • Ferrie, J. E.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)
  • Geuskens, G. A.TNO, Hoofddorp, Netherlands (författare)
  • Goldberg, M.Versailles-Saint Quentin University, Versailles, France,Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)
  • Hamer, M.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom,National Research Centre for the Working Environment, Copenhagen, Denmark (författare)
  • Hooftman, W. E.Karolinska Institutet (författare)
  • Houtman, I. L.TNO, Hoofddorp, Netherlands (författare)
  • Westerholm, Peter J. M.Uppsala universitet,Arbets- och miljömedicin(Swepub:uu)petwe427 (författare)
  • Jokela, M.Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland (författare)
  • Kittel, F.School of Public Health, Université Libre de Bruxelles, Brussels, Belgium (författare)
  • Knutsson, AndersMittuniversitetet,Institutionen för hälsovetenskap (-2013)(Swepub:miun)andknu (författare)
  • Koskenvuo, M.Department of Public Health, University of Helsinki, Helsinki, Finland (författare)
  • Koskinen, A.Finnish Institute of Occupational Health, Helsinki, Finland,School of Sociology, Social Policy and Social Work, Queen's University Belfast, Belfast, United Kingdom (författare)
  • Kouvonen, A.School of Sociology, Social Policy and Social Work, Queen's University Belfast, Belfast, United Kingdom (författare)
  • Kumari, M.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)
  • Madsen, I. E. H.National Research Centre for the Working Environment, Copenhagen, Denmark (författare)
  • Marmot, M. G.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)
  • Nielsen, M. L.Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Copenhagen, Denmark (författare)
  • Nordin, MariaUmeå universitet,Yrkes- och miljömedicin,Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå University, Umeå, Sweden(Swepub:umu)nonmaa98 (författare)
  • Oksanen, T.Finnish Institute of Occupational Health, Turku, Finland (författare)
  • Pentti, J.Finnish Institute of Occupational Health, Turku, Finland (författare)
  • Rugulies, R.National Research Centre for the Working Environment, Copenhagen, Denmark (författare)
  • Salo, P.Finnish Institute of Occupational Health, Turku, Finland (författare)
  • Siegrist, J.Department of Medical Sociology, University of Düsseldorf, Düsseldorf, Germany (författare)
  • Singh-Manoux, A.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)
  • Suominen, S. B.Department of Public Health, University of Turku, Turku, Finland (författare)
  • Väänänen, A.Finnish Institute of Occupational Health, Helsinki, Finland (författare)
  • Vahtera, J.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)
  • Virtanen, M.Finnish Institute of Occupational Health, Helsinki, Finland (författare)
  • Westerholm, P. J. M.Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland (författare)
  • Westerlund, HugoStockholms universitet,Stressforskningsinstitutet(Swepub:su)hwest (författare)
  • Zins, M.Versailles-Saint Quentin University, Versailles, France (författare)
  • Steptoe, A.Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom (författare)
  • Theorell, T.Stress Research Institute, Stockholm University, Stockholm, Sweden (författare)
  • Nyberg, Solja (författare)
  • Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United KingdomStressforskningsinstitutet (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:The Lancet: Elsevier380:9852, s. 1491-14970140-67361474-547X

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