Initial Disease Course and Treatment in an Inflammatory Bowel Disease Inception Cohort in Europe: The ECCO-EpiCom Cohort

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Initial Disease Course and Treatment in an Inflammatory Bowel Disease Inception Cohort in Europe : The ECCO-EpiCom Cohort

Burisch, Johan (författare): Med Sect, Ctr Digest Dis, Herlev Univ Hosp, Copenhagen, Denmark

Pedersen, Natalia (författare): Med Sect, Ctr Digest Dis, Herlev Univ Hosp, Copenhagen, Denmark

Cukovic-Cavka, Silvja (författare): Univ Hosp Ctr Zagreb, Div Gastroenterol & Hepatol, Univ Zagreb School of Medicine, Zagreb, Croatia

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Turk, Niksa (författare): Univ Hosp Ctr Zagreb, Div Gastroenterol & Hepatol, Univ Zagreb School of Medicine, Zagreb, Croatia

Kaimakliotis, Ioannis (författare): Nicosia Private Practice, Nicosia, Cyprus

Duricova, Dana (författare): IBD Ctr ISCARE, Charles Univ Prague, Prague, Czech Republic

Shonova, Olga (författare): Dept Gastroenterol, Hosp Ceske Budejovice, Ceske Budejovice, Czech Republic

Vind, Ida (författare): Dept Med, Amager Hosp, Amager, Denmark

Avnstrom, Soren (författare): Dept Med, Amager Hosp, Amager, Denmark

Thorsgaard, Niels (författare): Dept Med, Herning Cent Hosp, Herning, Denmark

Krabbe, Susanne (författare): Dept Med, Viborg Reg Hosp, Viborg, Denmark

Andersen, Vibeke (författare): Medical Department, Viborg Regional Hospital, Viborg, Denmark; Medical Department, Hospital of Southern Jutland, Aabenraa, Denmark; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark

Jens, Frederik Dahlerup (författare): Dept Med Hepatol & Gastroenterol 5, Aarhus Univ Hosp, Aarhus, Denmark

Kjeldsen, Jens (författare): Dept Med Gastroenterol, Odense Univ Hosp, Odense, Denmark

Salupere, Riina (författare): Div Gastroenterol & Endocrinol, Tartu Univ Hosp, Tartu, Estonia

Olsen, Jongero (författare): Dept Med, Natl Hosp Faroe Islands, Torshavn, Denmark

Nielsen, Kari Rubek (författare): Dept Med, Natl Hosp Faroe Islands, Torshavn, Denmark

Manninen, Pia (författare): Dept Gastroenterol & Alimentary Tract Surg, Tampere Univ Hosp, Tampere, Finland

Collin, Pekka (författare): Dept Gastroenterol & Alimentary Tract Surg, Tampere Univ Hosp, Tampere, Finland

Katsanos, Konstantinnos H. (författare): Div Internal Med 1, Univ Hosp, Ioannina, Greece ; Hepatogastroenterol Unit, Univ Hosp, Ioannina, Greece

Tsianos, Epameinondas V. (författare): Div Internal Med 1, Univ Hosp, Ioannina, Greece ; Hepatogastroenterol Unit, Univ Hosp, Ioannina, Greece

Ladefoged, Karin (författare): Dept Med, Dronning Ingrids Hosp, Nuuk, Greenland

Lakatos, Laszlo (författare): Dept Med, Csolnoky F Prov Hosp, Veszprem, Hungary

Bailey, Yvonne (författare): Adelaide & Meath Hosp, Dept Gastroenterol, Trinity Coll Dublin, Dublin, Ireland

O'Morain, Colm (författare): Dept Gastroenterol, Adelaide & Meath Hosp, Dublin, Ireland

Schwartz, Doron (författare): Dept Gastroenterol & Hepatol, Soroka Med Ctr, Beer Sheva, Israel; Ben Gurion Univ of the Negev, Beer Sheva, Israel

Odes, Selwyn (författare): Dept Gastroenterol & Hepatol, Soroka Med Ctr, Beer Sheva, Israel; Ben Gurion Univ of the Negev, Beer Sheva, Israel

Martinato, Matteo (författare): U.O. Gastroenterologia, Azienda Ospedaliera, Università di Padova, Padova, Italy

Lombardini, Silvia (författare): UO Medicina 38 e Gastroenterologia, Azienda Ospedaliera Arcispedale S Maria Nuova, Reggio Emilia, Italy

Jonaitis, Laimas (författare): Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania

Kupcinskas, Limas (författare): Department of Gastroenterology, State University of Medicine and Pharmacy of the Republic of Moldova, Chisinau, Moldova

Turcan, Svetlana (författare): Dept Gastroenterol, State Univ Med & Pharm Republ Moldova, Kishinev, Moldova

Barros, Louisa (författare): Dept Med, Hosp Vale de Sousa, Oporto, Portugal

Magro, Fernando (författare): Dept Gastroenterol, Hosp Sao Joao, Oporto, Portugal ; Inst Pharmacol & Therapeut, Oporto Med Sch, Oporto, Portugal ; Inst Mol & Cell Biol, Univ Porto, Oporto, Portugal

Lazar, Daniela (författare): Gastroenterol Clin, Univ Med 'Victor Babes', Timisoara, Romania

Goldis, Adrian (författare): Gastroenterol Clin, Univ Med 'Victor Babes', Timisoara, Romania

Nikulina, Inna (författare): Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russian Federation

Belousova, Elena (författare): Dept Gastroenterol, Moscow Reg Res Clin Inst, Moscow, Russia

Fernandez, Alberto (författare): Dept Gastroenterol, POVISA Hosp, Vigo, Spain

Hernandez, Vicent (författare): Dept Gastroenterol, Complexo Hospitalario Univ Vigo, Vigo, Spain

Almer, Sven (författare): Karolinska Institutet

Zhulina, Yaroslava, 1973- (författare): Örebro universitet,Institutionen för hälsovetenskap och medicin,Region Örebro län,Div Gastroenterol, Dept Med, Örebro University Hospital, Örebro, Sweden

Halfvarson, Jonas, 1970- (författare): Örebro universitet,Institutionen för läkarutbildning,Region Örebro län,Div Gastroenterol, Dept Med, Örebro University Hospital, Örebro, Sweden

Tsai, Her-Hsin (författare): Hull and East Yorkshire NHS Trust, Kingston-Upon-Hull, UK; Hull and York Medical School, Kingston-Upon-Hull, UK; Hull Royal Infirmary, Kingston-Upon-Hull, UK

Sebastian, Shaji (författare): Hull and East Yorkshire NHS Trust, Kingston-Upon-Hull, UK; Hull and York Medical School, Kingston-Upon-Hull, UK; Hull Royal Infirmary, Kingston-Upon-Hull, UK

Lakatos, Peter Laszlo (författare): Dept Med 1, Semmelweis Univ, Budapest, Hungary

Langholz, Ebbe (författare): Dept Med Gastroenterol, Gentofte Univ Hosp, Copenhagen, Denmark

Munkholm, Pia (författare): Med Sect, Ctr Digest Dis, Herlev Univ Hosp, Copenhagen, Denmark

EpiCom Northern Italy Centre Based in Crema and Cremona, Padova and Reggio Emilia, Italy (Lombardini & Martinato, on behalf of ), Group author (författare)

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Lippincott Williams & Wilkins, 2014
2014
Engelska.
Ingår i: Inflammatory Bowel Diseases. - : Lippincott Williams & Wilkins. - 1078-0998 .- 1536-4844. ; 20:1, s. 36-46

Relaterad länk:: https://urn.kb.se/re...; visa fler...; https://doi.org/10.1...; http://kipublication...; visa färre...

Tidskriftsartikel (refereegranskat)

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Background:The EpiCom cohort is a prospective, population-based, inception cohort of inflammatory bowel disease (IBD) patients from 31 European centers covering a background population of 10.1 million. The aim of this study was to assess the 1-year outcome in the EpiCom cohort.Methods:Patients were followed-up every third month during the first 12 (3) months, and clinical data, demographics, disease activity, medical therapy, surgery, cancers, and deaths were collected and entered in a Web-based database (www.epicom-ecco.eu).Results:In total, 1367 patients were included in the 1-year follow-up. In western Europe, 65 Crohn's disease (CD) (16%), 20 ulcerative colitis (UC) (4%), and 4 IBD unclassified (4%) patients underwent surgery, and in eastern Europe, 12 CD (12%) and 2 UC (1%) patients underwent surgery. Eighty-one CD (20%), 80 UC (14%), and 13 (9%) IBD unclassified patients were hospitalized in western Europe compared with 17 CD (16%) and 12 UC (8%) patients in eastern Europe. The cumulative probability of receiving immunomodulators was 57% for CD in western (median time to treatment 2 months) and 44% (1 month) in eastern Europe, and 21% (5 months) and 5% (6 months) for biological therapy, respectively. For UC patients, the cumulative probability was 22% (4 months) and 15% (3 months) for immunomodulators and 6% (3 months) and 1% (12 months) for biological therapy, respectively in the western and eastern Europe.Discussion:In this cohort, immunological therapy was initiated within the first months of disease. Surgery and hospitalization rates did not differ between patients from eastern and western Europe, although more western European patients received biological agents and were comparable to previous population-based inception cohorts.

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Av författaren/redakt...: Burisch, Johan; Pedersen, Natali ...; Cukovic-Cavka, S ...; Turk, Niksa; Kaimakliotis, Io ...; Duricova, Dana; visa fler...; Shonova, Olga; Vind, Ida; Avnstrom, Soren; Thorsgaard, Niel ...; Krabbe, Susanne; Andersen, Vibeke; Jens, Frederik D ...; Kjeldsen, Jens; Salupere, Riina; Olsen, Jongero; Nielsen, Kari Ru ...; Manninen, Pia; Collin, Pekka; Katsanos, Konsta ...; Tsianos, Epamein ...; Ladefoged, Karin; Lakatos, Laszlo; Bailey, Yvonne; O'Morain, Colm; Schwartz, Doron; Odes, Selwyn; Martinato, Matte ...; Lombardini, Silv ...; Jonaitis, Laimas; Kupcinskas, Lima ...; Turcan, Svetlana; Barros, Louisa; Magro, Fernando; Lazar, Daniela; Goldis, Adrian; Nikulina, Inna; Belousova, Elena; Fernandez, Alber ...; Hernandez, Vicen ...; Almer, Sven; Zhulina, Yarosla ...; Halfvarson, Jona ...; Tsai, Her-Hsin; Sebastian, Shaji; Lakatos, Peter L ...; Langholz, Ebbe; Munkholm, Pia; EpiCom Northern ...; visa färre...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Gastroenterologi

Artiklar i publikationen: Inflammatory Bow ...

Av lärosätet: Örebro universitet; Karolinska Institutet

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Initial Disease Course and Treatment in an Inflammatory Bowel Disease Inception Cohort in Europe : The ECCO-EpiCom Cohort

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