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  • Heikkila, K.Finnish Institute of Occupational Health, Uimalankatu 1, 33540 Tampere, Finland,Finnish Institute of Occupational Health, Helsinki, Finland (author)

Job strain and the risk of severe asthma exacerbations : a meta-analysis of individual-participant data from 100 000 European men and women

  • Article/chapterEnglish2014

Publisher, publication year, extent ...

  • 2014-04-12
  • Wiley,2014
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:su-105517
  • https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-105517URI
  • https://doi.org/10.1111/all.12381DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-90409URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-22049URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-23706URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:129019111URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-227699URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • AuthorCount:32;
  • Language of Original Document: English
  • BackgroundMany patients and healthcare professionals believe that work-related psychosocial stress, such as job strain, can make asthma worse, but this is not corroborated by empirical evidence. We investigated the associations between job strain and the incidence of severe asthma exacerbations in working-age European men and women. MethodsWe analysed individual-level data, collected between 1985 and 2010, from 102 175 working-age men and women in 11 prospective European studies. Job strain (a combination of high demands and low control at work) was self-reported at baseline. Incident severe asthma exacerbations were ascertained from national hospitalization and death registries. Associations between job strain and asthma exacerbations were modelled using Cox regression and the study-specific findings combined using random-effects meta-analyses. ResultsDuring a median follow-up of 10years, 1 109 individuals experienced a severe asthma exacerbation (430 with asthma as the primary diagnostic code). In the age- and sex-adjusted analyses, job strain was associated with an increased risk of severe asthma exacerbations defined using the primary diagnostic code (hazard ratio, HR: 1.27, 95% confidence interval, CI: 1.00, 1.61). This association attenuated towards the null after adjustment for potential confounders (HR: 1.22, 95% CI: 0.96, 1.55). No association was observed in the analyses with asthma defined using any diagnostic code (HR: 1.01, 95% CI: 0.86, 1.19). ConclusionsOur findings suggest that job strain is probably not an important risk factor for severe asthma exacerbations leading to hospitalization or death.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Madsen, I. E. H.National Research Centre for the Working Environment, Copenhagen, Denmark (author)
  • Theorell, TöresStockholms universitet,Karolinska Institutet,Stressforskningsinstitutet,Enheten för epidemiologi(Swepub:su)ttheo (author)
  • Fransson, EleonorKarolinska Institutet,Jönköping University,Stockholms universitet,Stressforskningsinstitutet,Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Stress Research Institute, Stockholm University, Stockholm, Sweden,HHJ, Avdelningen för naturvetenskap och biomedicin,HHJ. ADULT(Swepub:hj)FrEl (author)
  • Westerlund, HugoKarolinska Institutet,Stockholms universitet,Stressforskningsinstitutet,Epidemiologi,Stress Research Institute, Stockholm University, Stockholm, Sweden(Swepub:su)hwest (author)
  • Westerholm, Peter J. M.Uppsala universitet,Arbets- och miljömedicin(Swepub:uu)petwe427 (author)
  • Virtanen, M.Finnish Institute of Occupational Health, Uimalankatu 1, 33540 Tampere, Finland,Finnish Institute of Occupational Health, Helsinki, Finland (author)
  • Vahtera, J.Finnish Institute of Occupational Health, Turku, Finland; Department of Public Health, University of Turku, Turku, Finland (author)
  • Vaananen, A.Finnish Institute of Occupational Health, Uimalankatu 1, 33540 Tampere, Finland,Finnish Institute of Occupational Health, Helsinki, Finland (author)
  • Theorell, TöresStockholms universitet,Stressforskningsinstitutet,Enheten för epidemiologi,Finnish Institute of Occupational Health, Turku, Finland(Swepub:su)ttheo (author)
  • Suominen, S. B.Department of Public Health, University of Turku, Turku, Finland; Folkhälsan Research Center, Helsinki, Finland; Nordic School of Public Health, Göteborg, Sweden (author)
  • Shipley, M. J.Department of Epidemiology and Public Health, University College London, London, United Kingdom (author)
  • Salo, P.Department of Public Health and Department of Psychology, University of Turku, Turku, Finland (author)
  • Rugulies, R.National Research Centre for the Working Environment, Copenhagen, Denmark; Department of Public Health, Department of Psychology, University of Copenhagen, Copenhagen, Denmark (author)
  • Pentti, J. (author)
  • Pejtersen, J. H.The Danish National Centre for Social Research, Copenhagen, Denmark (author)
  • Oksanen, T. (author)
  • Nordin, MariaUmeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden(Swepub:umu)nonmaa98 (author)
  • Nielsen, M. L.Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Copenhagen, Denmark (author)
  • Kouvonen, A.School of Sociology Social Policy and Social Work, Queen's University Belfast, Belfast, United Kingdom,Finnish Institute of Occupational Health, Uimalankatu 1, 33540 Tampere, Finland,Finnish Institute of Occupational Health, Helsinki, Finland (author)
  • Koskinen, A. (author)
  • Koskenvuo, M.Department of Public Health, University of Helsinki, Helsinki, Finland (author)
  • Knutsson, AndersMittuniversitetet,Avdelningen för hälsovetenskap,Department of Health Sciences, Mid Sweden University, Sundsvall, Sweden(Swepub:miun)andknu (author)
  • Ferrie, J. E.Uppsala universitet,Arbets- och miljömedicin (author)
  • Dragano, N.Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany (author)
  • Burr, H.Federal Institute for Occupational Safety and Health (BAuA), Berlin, Germany (author)
  • Borritz, M.Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Copenhagen, Denmark (author)
  • Bjorner, J. B.National Research Centre for the Working Environment, Copenhagen, Denmark (author)
  • Alfredsson, L.Karolinska Institutet (author)
  • Batty, G. D.Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom,Department of Epidemiology and Public Health, University College London, London, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK (author)
  • Singh-Manoux, A.Department of Epidemiology and Public Health, University College London, London, UK; Inserm U1018, Centre for Research in Epidemiology and Population Health, Villejuif, France (author)
  • Kivimaki, M.Finnish Institute of Occupational Health, Uimalankatu 1, 33540 Tampere, Finland,Finnish Institute of Occupational Health, Helsinki, Finland; Department of Epidemiology and Public Health, University College London, London, UK (author)
  • Finnish Institute of Occupational Health, Uimalankatu 1, 33540 Tampere, FinlandFinnish Institute of Occupational Health, Helsinki, Finland (creator_code:org_t)

Related titles

  • In:Allergy. European Journal of Allergy and Clinical Immunology: Wiley69:6, s. 775-7830105-45381398-9995

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