Tyck till om SwePub Sök
här!
Sökning: L773:1479 683X
> (1994) >
[111In-DTPA-D-Phe1]...
-
Tiensuu Janson, EvaUppsala universitet,Medicin,onkologisk endokrinologi
(författare)
[111In-DTPA-D-Phe1]octreotide scintigraphy in patients with carcinoid tumours : the predictive value for somatostatin analogue treatment
- Artikel/kapitelEngelska1994
Förlag, utgivningsår, omfång ...
-
Oxford University Press (OUP),1994
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:uu-21440
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-21440URI
-
https://doi.org/10.1530/eje.0.1310577DOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
This study was performed to evaluate whether the presence or absence of somatostatin receptors in malignant carcinoid tumours detected by [111In-DTPA-D-Phe1]octreotide scintigraphy can be used to predict response to somatostatin analogue treatment. Thirty patients were investigated, 28 with midgut carcinoid tumours and two with foregut carcinoid tumours. Twenty-seven patients showed pathological uptake in tumour lesions at scintigraphy; of these, 22 responded to somatostatin analogue treatment using octreotide, somatuline or octastatin, while five patients failed to respond. None of the three patients displaying negative scintigraphic investigations responded to treatment with somatostatin analogues. These results show a good correlation between the somatostatin receptor status and the patients' ability to respond to somatostatin analogue treatment (p = 0.014). We conclude that somatostatin receptor scintigraphy using [111In-DTPA-D-Phe1]octreotide can be used to select patients with malignant carcinoid tumours suitable for somatostatin analogue treatment and exclude those that will not benefit from such medication.
Ämnesord och genrebeteckningar
-
Aged
-
Carcinoid Tumor/*diagnosis/drug therapy
-
Female
-
Forecasting
-
Humans
-
Indium Radioisotopes/diagnostic use
-
Intestinal Neoplasms/*diagnosis/drug therapy
-
Male
-
Middle Aged
-
Octreotide/*analogs & derivatives/diagnostic use/therapeutic use
-
Pentetic Acid/*analogs & derivatives/diagnostic use
-
Peptides; Cyclic
-
Prospective Studies
-
Radionuclide Imaging
-
Retrospective Studies
-
Somatostatin/analogs & derivatives/therapeutic use
-
Tomography; X-Ray Computed
-
Treatment Outcome
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Westlin, J E
(författare)
-
Eriksson, B
(författare)
-
Ahlström, HåkanUppsala universitet,Enheten för radiologi
(författare)
-
Nilsson, SvenUppsala universitet,Enheten för radiologi
(författare)
-
Öberg, KjellUppsala universitet,Medicin
(författare)
-
Uppsala universitetMedicin
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:European Journal of Endocrinology: Oxford University Press (OUP)131:6, s. 577-5810804-46431479-683X
Internetlänk
Hitta via bibliotek
Till lärosätets databas