Results after sacral nerve stimulation for chronic constipation

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BACKGROUND: Sacral nerve stimulation is an established treatment for fecal incontinence and initial reports describe successful results also in subjects with chronic constipation.METHODS: Consecutive patients with slow transit or outlet obstruction type constipation were offered external stimulation through a test electrode inserted in a sacral foramen during a 3-week period. The symptomatic evaluation was based on the number of bowel movements and a validated obstructed defecation score (ODS). A permanent implant was performed provided an overall 50% decrease in symptoms was observed.KEY RESULTS: In total, 44 patients with chronic constipation were treated with a 3-week test stimulation. Fifteen experienced a 50% reduction of symptoms and received a permanent implant. Four of the 15 with permanent implants were explanted during the course of the study. Five subjects (11% of original group) reported sustained symptom relief at final follow-up after a mean of 24 months (range 4-81). Mean ODS score did not change during the treatment. Patients with predominantly slow transit constipation or outlet obstruction did not differ concerning success rate.CONCLUSIONS & INFERENCES: Sacral nerve stimulation has limited efficacy in unselected patients with chronic constipation and cannot be recommended for treatment on routine basis.

Sonesson, A-C (författare)
Lindberg, B (författare)
Åkerud, PeterUppsala universitet,Kolorektalkirurgi(Swepub:uu)petak537 (författare)
Karlbom, UrbanUppsala universitet,Kolorektalkirurgi(Swepub:uu)urbakarl (författare)
Uppsala universitetKolorektalkirurgi (creator_code:org_t)

Ingår i:Neurogastroenterology and Motility: Wiley27:5, s. 734-7391350-19251365-2982

Av författaren/redakt...: Graf, Wilhelm; Sonesson, A-C; Lindberg, B; Åkerud, Peter; Karlbom, Urban

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