Combined effects of smoking and HPV16 in oropharyngeal cancer

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Sökning: WFRF:(Canova Cristina) > Grioni Sara > Combined effects of...

1 av 1
Föregående post
Nästa post
Till träfflistan

Anantharaman, DevasenaInt Agcy Res Canc, Genet Epidemiol Grp, Lyon, France.,International Agency for Research on Cancer, World Health Organization (författare)

Combined effects of smoking and HPV16 in oropharyngeal cancer

Artikel/kapitelEngelska2016

Förlag, utgivningsår, omfång ...

2016-05-19
Oxford University Press (OUP),2016
printrdacarrier

Nummerbeteckningar

LIBRIS-ID:oai:DiVA.org:uu-306775
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-306775URI
https://doi.org/10.1093/ije/dyw069DOI
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-122088URI
https://lup.lub.lu.se/record/ee36fb8b-9d06-4474-a0cc-77df864f16eeURI
http://kipublications.ki.se/Default.aspx?queryparsed=id:134321351URI

Kompletterande språkuppgifter

Språk:engelska
Sammanfattning på:engelska

Ingår i deldatabas

SwePubSwePub

Klassifikation

Ämneskategori:ref swepub-contenttype
Ämneskategori:art swepub-publicationtype

Anmärkningar

Funding: The ARCAGE study was supported by a grant from the European Commission's 5th Framework Program (contract QLK1-2001-00182). The EPIC study has been supported by the Europe Against Cancer Program of the European Commission (SANCO); Deutsche Krebshilfe, Deutsches Krebsforschungszentrum, German Federal Ministry of Education and Research; Danish Cancer Society; Health Research Fund (FIS) of the Spanish Ministry of Health, Spanish Regional Governments of Andalucia, Asturias, Basque Country, Murcia and Navarra; Catalan Institute of Oncology, Spain; the ISCIII of the Spanish Ministry of Health (RETICC DR06/0020); Cancer Research UK; Medical Research Council, UK; Greek Ministry of Health; Stavros Niarchos Foundation; Hellenic Health Foundation; Italian Association for Research on Cancer (AIRC); Italian National Research Council, Fondazione-IstitutoBanco Napoli, Italy; Associazione Italiana per la Ricerca sul Cancro-AIRC Milan; Compagnia di San Paolo; Dutch Ministry of Public Health, Welfare and Sports; World Cancer Research Fund; Swedish Cancer Society; Swedish Scientific Council; Regional Government of Vasterbotten, Sweden; NordForsk (Centre of excellence programme HELGA), Norway; French League against Cancer (LNCC), France; National Institute for Health and Medical Research (INSERM), France; Mutuelle Generale de l'Education Nationale (MGEN), France; 3M Co, France; Gustave Roussy Institute (IGR), France; and General Councils of France. The serology testing of EPIC prospective study was supported by the National Cancer Institute Intramural Research Program. The work done in this study was supported in part by a grant from the European Commission's 7th Framework Program (contract FP7-HEALTH-2011-282562) and partly by the Health General Directorate of the French Social Affairs and Health Ministry.
Background: Although smoking and HPV infection are recognized as important risk factors for oropharyngeal cancer, how their joint exposure impacts on oropharyngeal cancer risk is unclear. Specifically, whether smoking confers any additional risk to HPV-positive oropharyngeal cancer is not understood.Methods: Using HPV serology as a marker of HPV-related cancer, we examined the interaction between smoking and HPV16 in 459 oropharyngeal (and 1445 oral cavity and laryngeal) cancer patients and 3024 control participants from two large European multicentre studies. Odds ratios and credible intervals [CrI], adjusted for potential confounders, were estimated using Bayesian logistic regression.Results: Both smoking [odds ratio (OR [CrI]: 6.82 [4.52, 10.29]) and HPV seropositivity (OR [CrI]: 235.69 [99.95, 555.74]) were independently associated with oropharyngeal cancer. The joint association of smoking and HPV seropositivity was consistent with that expected on the additive scale (synergy index [CrI]: 1.32 [0.51, 3.45]), suggesting they act as independent risk factors for oropharyngeal cancer.Conclusions: Smoking was consistently associated with increase in oropharyngeal cancer risk in models stratified by HPV16 seropositivity. In addition, we report that the prevalence of oropharyngeal cancer increases with smoking for both HPV16-positive and HPV16-negative persons. The impact of smoking on HPV16-positive oropharyngeal cancer highlights the continued need for smoking cessation programmes for primary prevention of head and neck cancer.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Cancer och onkologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cancer and Oncology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Public Health, Global Health, Social Medicine and Epidemiology hsv//eng
Human papillomavirus
tobacco smoking
interaction
head and neck cancer risk
oropharynx cancer
Journal Article

Biuppslag (personer, institutioner, konferenser, titlar ...)

Muller, David C.Int Agcy Res Canc, Genet Epidemiol Grp, Lyon, France.,International Agency for Research on Cancer, World Health Organization,University of Padova (författare)
Lagiou, PagonaUniv Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece. (författare)
Ahrens, WolfgangBIPS, Leibniz Inst Prevent Res & Epidemiol, Bremen, Germany.;Univ Bremen, Fac Math & Comp Sci, Bremen, Germany.,Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH (författare)
Holcatova, IvanaCharles Univ Prague, Fac Med 1, Inst Hyg & Epidemiol, Prague, Czech Republic.,Charles University in Prague (författare)
Merletti, FrancoUniv Turin, Dept Med Sci, Canc Epidemiol Unit, Turin, Italy.,University of Turin (författare)
Kjaerheim, KristinaCanc Registry Norway, Oslo, Norway.,Cancer Registry of Norway, Institute of Population-Based Cancer Research (författare)
Polesel, JerryCRO Aviano Natl Canc Inst, Unit Epidemiol & Biostat, Aviano, Italy.,CRO (Centro di Riferimento Oncologico) Aviano National Cancer Institute (författare)
Simonato, LorenzoUniv Padua, Dept Mol Med, Lab Publ Hlth & Populat Studies, Padua, Italy.,University of Padova (författare)
Canova, CristinaUniv Padua, Dept Mol Med, Lab Publ Hlth & Populat Studies, Padua, Italy. (författare)
Castellsague, XavierCIBERESP, IDIBELL, ICO, Unit Infect & Canc, Barcelona, Spain.,L'Hospitalet de Llobregat, Barcelona (författare)
Macfarlane, Tatiana V.Univ Aberdeen, Sch Med & Dent, Aberdeen, Scotland.,University of Aberdeen (författare)
Znaor, ArianaCroatian Natl Inst Publ Hlth, Croatian Natl Canc Registry, Zagreb, Croatia.;Int Agcy Res Canc, Sect Canc Surveillance, Lyon, France.,Croatian National Institute of Public Health, Zagreb (författare)
Thomson, PeterNewcastle Univ, Ctr Oral Hlth Res, Newcastle Upon Tyne, Tyne & Wear, England.,University of Newcastle upon Tyne (författare)
Robinson, MaxNewcastle Univ, Ctr Oral Hlth Res, Newcastle Upon Tyne, Tyne & Wear, England.,University of Newcastle upon Tyne (författare)
Conway, David I.Univ Glasgow, Sch Dent, Coll Med Vet & Life Sci, Glasgow, Lanark, Scotland.,University of Glasgow (författare)
Healy, Claire M.Trinity Coll Dublin, Sch Dent Sci, Dublin, Ireland.,Trinity College Dublin (författare)
Tjönneland, AnneDanish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark.,Danish Cancer Society (författare)
Westin, UllaLund University,Lunds universitet,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups(Swepub:lu)oron-upe (författare)
Ekström, JohannaLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Klinisk mikrobiologi, Malmö,Internal Medicine - Epidemiology,Lund University Research Groups,Clinical Microbiology, Malmö(Swepub:lu)mikr-jku (författare)
Chang-Claude, JennyGerman Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany.,German Cancer Research Centre (författare)
Kaaks, RudolfGerman Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany.,German Cancer Research Centre (författare)
Overvad, KimInst Publ Hlth, Aarhus, Denmark.,Aarhus University (författare)
Drogan, DagmarGerman Inst Human Nutr Potsdam Rehbruecke DIfE, Nuthetal, Germany.,German Institute of Human Nutrition (författare)
Hallmans, GöranUmeå University,Umeå universitet,Enheten för biobanksforskning(Swepub:umu)goha0001 (författare)
Laurell, GöranUppsala University,Uppsala universitet,Öron-, näs- och halssjukdomar(Swepub:uu)gorla772 (författare)
Bueno-de-Mesquita, H. B.Natl Inst Publ Hlth & Environm RIVM, Dept Determinants Chron Dis DCD, Bilthoven, Netherlands.;Univ Med Ctr, Dept Gastroenterol & Hepatol, Utrecht, Netherlands.;Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Univ Malaya, Fac Med, Dept Social & Prevent Med, Kuala Lumpur, Malaysia. (författare)
Peeters, Petra H.Univ Med Ctr, Julius Ctr Hlth Sci & Primary Care, Dept Epidemiol, Utrecht, Netherlands.;Imperial Coll London, Sch Publ Hlth, MRC PHE, London, England. (författare)
Agudo, AntonioICO, Unit Nutr & Canc, Barcelona, Spain.,L'Hospitalet de Llobregat, Barcelona (författare)
Larranaga, NereaBIODonostia Res Inst, Basque Hlth Dept, Publ Hlth Div Gipuzkoa, San Sebastian, Spain.;CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain.,Biodonostia Health Research Institute,CIBER Epidemiology and Public Health (CIBERESP) (författare)
Travis, Ruth C.Univ Oxford, Nuffield Dept Populat Hlth, Canc Epidemiol Unit, Oxford, England. (författare)
Palli, DomenicoCanc Res & Prevent Inst ISPO, Mol & Nutr Epidemiol Unit, Florence, Italy. (författare)
Barricarte, AurelioCIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain.;Navarre Publ Hlth Inst, Pamplona, Spain.,CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA) (författare)
Trichopoulou, AntoniaHellen Hlth Fdn, Athens, Greece.;Acad Athens, Bur Epidemiol Res, Athens, Greece.,Academy of Athens (författare)
George, SaitakisUniv Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece.;Hellen Hlth Fdn, Athens, Greece.,National and Kapodistrian University of Athens (författare)
Trichopoulos, DimitriosHellen Hlth Fdn, Athens, Greece.;Acad Athens, Bur Epidemiol Res, Athens, Greece.;Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.,Harvard University,Academy of Athens (författare)
Ramon Quiros, J.Publ Hlth Directorate Asturias, Oviedo, Spain. (författare)
Grioni, SaraFdn IRCCS, Ist Nazl Tumori, Epidemiol & Prevent Unit, Milan, Italy.,Istituto Nazionale dei Tumori (författare)
Sacerdote, CarlottaUniv Turin, Citta Salute & Sci Hosp, Canc Epidemiol Unit, Turin, Italy.;Ctr Canc Prevent CPO, Turin, Italy.,Centre for Cancer Epidemiology and Prevention (CPO Piemonte) (författare)
Navarro, CarmenCIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain.;IMIB Arrixaca, Murcia Reg Hlth Council, Dept Epidemiol, Murcia, Spain.;Univ Murcia, Dept Hlth & Social Sci, Murcia, Spain.,University of Murcia,CIBER Epidemiology and Public Health (CIBERESP) (författare)
Sanchez, Maria-JoseCIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain.;Univ Granada, Inst Invest Biosanitaria, Granada, Spain.,University of Granada,CIBER Epidemiology and Public Health (CIBERESP) (författare)
Tumino, RosarioCiv MP Arezzo Hosp, Canc Registry, Asp Ragusa, Ragusa, Italy.;Civ MP Arezzo Hosp, Histopathol Unit, Asp Ragusa, Ragusa, Italy. (författare)
Severi, GianlucaHuman Genet Fdn HuGeF, Turin, Italy.;Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic 3010, Australia.,University of Melbourne,Human Genetics Foundation (HuGeF) (författare)
Boutron-Ruault, Marie-ChristineINSERM, Ctr Res Epidemiol & Populat Hlth CESP, Villejuif, France.;Univ Paris 11, Villejuif, France.;Inst Gustave Roussy, Villejuif, France.,University of Paris-Saclay (författare)
Clavel-Chapelon, FrancoiseINSERM, Ctr Res Epidemiol & Populat Hlth CESP, Villejuif, France.;Univ Paris 11, Villejuif, France.;Inst Gustave Roussy, Villejuif, France. (författare)
Panico, SalvatoreUniv Naples Federico II, Dipartimento Med Clin & Chirurgia, Naples, Italy.,University of Naples Federico II (författare)
Weiderpass, ElisabeteKarolinska Institutet,Folkhälsan Research Center,UiT The Arctic University of Norway, Tromsø,Cancer Registry of Norway, Institute of Population-Based Cancer Research (författare)
Lund, EilivArctic Univ Norway, Univ Tromso, Fac Hlth Sci, Dept Community Med, Tromso, Norway.,UiT The Arctic University of Norway, Tromsø (författare)
Gram, Inger T.Arctic Univ Norway, Univ Tromso, Fac Hlth Sci, Dept Community Med, Tromso, Norway.,UiT The Arctic University of Norway, Tromsø (författare)
Riboli, ElioImperial Coll London, Sch Publ Hlth, London, England.,Imperial College London (författare)
Pawlita, MichaelGerman Canc Res Ctr, Heidelberg, Germany.,German Cancer Research Centre (författare)
Waterboer, TimGerman Canc Res Ctr, Heidelberg, Germany.,German Cancer Research Centre (författare)
Kreimer, Aimee R.NCI, NIH, Bethesda, MD 20892 USA.,National Cancer Institute, NCI (författare)
Johansson, MattiasUmeå universitet,Enheten för biobanksforskning,International Agency for Research on Cancer, World Health Organization (författare)
Brennan, PaulInt Agcy Res Canc, Genet Epidemiol Grp, Lyon, France.,International Agency for Research on Cancer, World Health Organization (författare)
Int Agcy Res Canc, Genet Epidemiol Grp, Lyon, France.International Agency for Research on Cancer, World Health Organization (creator_code:org_t)

Sammanhörande titlar

Ingår i:International Journal of Epidemiology: Oxford University Press (OUP)45:3, s. 752-7610300-57711464-3685

Internetlänk

Hitta via bibliotek

International Journal of Epidemiology (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

1 av 1
Föregående post
Nästa post
Till träfflistan

Hitta mer i SwePub

Av författaren/redakt...: Anantharaman, De ...; Muller, David C.; Lagiou, Pagona; Ahrens, Wolfgang; Holcatova, Ivana; Merletti, Franco; visa fler...; Kjaerheim, Krist ...; Polesel, Jerry; Simonato, Lorenz ...; Canova, Cristina; Castellsague, Xa ...; Macfarlane, Tati ...; Znaor, Ariana; Thomson, Peter; Robinson, Max; Conway, David I.; Healy, Claire M.; Tjönneland, Anne; Westin, Ulla; Ekström, Johanna; Chang-Claude, Je ...; Kaaks, Rudolf; Overvad, Kim; Drogan, Dagmar; Hallmans, Göran; Laurell, Göran; Bueno-de-Mesquit ...; Peeters, Petra H ...; Agudo, Antonio; Larranaga, Nerea; Travis, Ruth C.; Palli, Domenico; Barricarte, Aure ...; Trichopoulou, An ...; George, Saitakis; Trichopoulos, Di ...; Ramon Quiros, J.; Grioni, Sara; Sacerdote, Carlo ...; Navarro, Carmen; Sanchez, Maria-J ...; Tumino, Rosario; Severi, Gianluca; Boutron-Ruault, ...; Clavel-Chapelon, ...; Panico, Salvator ...; Weiderpass, Elis ...; Lund, Eiliv; Gram, Inger T.; Riboli, Elio; Pawlita, Michael; Waterboer, Tim; Kreimer, Aimee R ...; Johansson, Matti ...; Brennan, Paul; visa färre...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Cancer och onkol ...

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Hälsovetenskap; och Folkhälsovetensk ...

Artiklar i publikationen: International Jo ...

Av lärosätet: Uppsala universitet; Umeå universitet; Lunds universitet; Karolinska Institutet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se