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Sökning: WFRF:(O'Brien Eoin) > (2020-2021) > Isolated Diastolic ...

Isolated Diastolic Hypertension in the IDACO Study : An Age-Stratified Analysis Using 24-Hour Ambulatory Blood Pressure Measurements

McEvoy, John W. (författare)
Natl Univ Ireland Galway, Sch Med, Galway, Ireland.;Natl Inst Prevent & Cardiovasc Hlth, Galway, Ireland.
Yang, Wen-Yi (författare)
Shanghai Jiao Tong Univ, Sch Med, Shanghai Gen Hosp, Dept Cardiol, Shanghai, Peoples R China.
Thijs, Lutgarde (författare)
Univ Leuven, KU Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium.
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Zhang, Zhen-Yu (författare)
Univ Leuven, KU Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium.
Melgarejo, Jesus D. (författare)
Univ Leuven, KU Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium.
Boggia, Jose (författare)
Univ Republica, Hosp Clin, Ctr Nefrol, Montevideo, Uruguay.;Univ Republica, Dept Fisiopatol, Montevideo, Uruguay.
Hansen, Tine W. (författare)
Steno Diabet Ctr Copenhagen, Gentofte, Denmark.;Ctr Hlth, Copenhagen, Denmark.
Asayama, Kei (författare)
Univ Leuven, KU Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium.;Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan.;Teikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan.
Ohkubo, Takayoshi (författare)
Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan.;Teikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan.
Dolan, Eamon (författare)
Connolly Hosp, Stroke & Hypertens Unit, Geriatr Med, Dublin, Ireland.
Stolarz-Skrzypek, Katarzyna (författare)
Jagiellonian Univ Med Coll, Dept Cardiol Intervent Electrocardiol & Hypertens, Krakow, Poland.
Malyutina, Sofia (författare)
Russian Acad Sci, Inst Cytol & Genet, Siberian Branch, Novosibirsk, Russia.;Inst Internal & Prevent Med, Novosibirsk, Russia.
Casiglia, Edoardo (författare)
Univ Padua, Dept Med, Padua, Italy.
Lind, Lars (författare)
Uppsala universitet,Geriatrik
Filipovsky, Jan (författare)
Charles Univ Prague, Fac Med, Plzen, Czech Republic.
Maestre, Gladys E. (författare)
Univ Zulia, Inst Cardiovasc, Maracaibo, Venezuela.;Univ Zulia, Lab Neurociencias, Maracaibo, Venezuela.;Univ Texas Rio Grande Valley, Sch Med, Dept Human Genet, Brownsville, TX USA.;Univ Texas Rio Grande Valley, Sch Med, Dept Biomed Sci, Div Neurosci, Brownsville, TX USA.
Li, Yan (författare)
Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Shanghai Inst Hypertens,Ctr Vasc Evaluat, Shanghai, Peoples R China.;Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies & Clin Trials, Shanghai, Peoples R China.
Wang, Ji-Guang (författare)
Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Shanghai Inst Hypertens,Ctr Vasc Evaluat, Shanghai, Peoples R China.;Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies & Clin Trials, Shanghai, Peoples R China.
Imai, Yutaka (författare)
Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan.
Kawecka-Jaszcz, Kalina (författare)
Jagiellonian Univ Med Coll, Dept Cardiol Intervent Electrocardiol & Hypertens, Krakow, Poland.
Sandoya, Edgardo (författare)
Asoc Espanola Primera Socorros Mutuos, Montevideo, Uruguay.
Narkiewicz, Krzysztof (författare)
Med Univ Gdansk, Dept Hypertens & Diabetol, Hypertens Unit, Gdansk, Poland.
O'Brien, Eoin (författare)
Univ Coll Dublin, Conway Inst Biomol & Biomed Res, Dublin, Ireland.
Vanassche, Thomas (författare)
Univ Leuven, KU Leuven, Dept Cardiovasc Sci, Ctr Mol & Vasc Biol, Leuven, Belgium.
Staessen, Jan A. (författare)
Univ Leuven, Fac Med, Biomed Sci Grp, Leuven, Belgium.;Res Inst Alliance Promot Prevent Med, Leopoldstraat 59, BE-2800 Mecehelen, Belgium.
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Natl Univ Ireland Galway, Sch Med, Galway, Ireland;Natl Inst Prevent & Cardiovasc Hlth, Galway, Ireland. Shanghai Jiao Tong Univ, Sch Med, Shanghai Gen Hosp, Dept Cardiol, Shanghai, Peoples R China. (creator_code:org_t)
Wolters Kluwer, 2021
2021
Engelska.
Ingår i: Hypertension. - : Wolters Kluwer. - 0194-911X .- 1524-4563. ; 78:5, s. 1222-1231
Relaterad länk:
https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
https://urn.kb.se/re...
https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • The prognostic implications of isolated diastolic hypertension (IDH), as defined by 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines, have not been tested using ambulatory blood pressure (BP) monitor thresholds (ie, 24-hour mean systolic BP <125 mm Hg and diastolic BP >= 75 mm Hg). We analyzed data from 11 135 participants in the IDACO (International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes). Using 24-hour mean ambulatory BP monitor values, we performed Cox regression testing independent associations of IDH with death or cardiovascular events. Analyses were conducted in the cohort overall, as well as after age stratification (<50 years versus >= 50 years). The median age at baseline was 54.7 years and 49% were female. Over a median follow-up of 13.8 years, 2836 participants died, and 2049 experienced a cardiovascular event. Overall, irrespective of age, IDH on 24-hour ambulatory BP monitor defined by 2017 American College of Cardiology/American Heart Association criteria was not significantly associated with death (hazard ratio, 0.95 [95% CI, 0.79-1.13]) or cardiovascular events (hazard ratio, 1.14 [95% CI, 0.94-1.40]), compared with normotension. However, among the subgroup <50 years old, IDH was associated with excess risk for cardiovascular events (2.87 [95% CI, 1.72-4.80]), with evidence for effect modification based on age (P interaction <0.001). In conclusion, using ambulatory BP monitor data, this study suggests that IDH defined by 2017 American College of Cardiology/American Heart Association criteria is not a risk factor for cardiovascular disease in adults aged 50 years or older but is a risk factor among younger adults. Thus, age is an important consideration in the clinical management of adults with IDH.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

blood pressure
hypertension
morbidity
mortality
risk

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

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