Scleroderma

• In their review article on scleroderma, Gabrielli et al. incorporate their earlier observations that all patients with this disease have activating antibodies to platelet-derived growth factor (PDGF) receptors (PDGFRs). These antibodies were described as being specific for scleroderma and for chronic extensive graft-versus-host disease, two conditions that share some clinical features. The review does not reflect the current debate on the existence of such antibodies. Researchers from several centers, including ours, have challenged the results of Gabrielli et al.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Nyckelord

Scleroderma

PDGF

autoantibodies

Internal medicine

Invärtesmedicin

Medicin

Medicine

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)