Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial.

• Lowering of LDL cholesterol reduces major vascular events, but whether more intensive therapy safely produces extra benefits is uncertain. We aimed to establish efficacy and safety of more intensive statin treatment in patients at high cardiovascular risk.

Nyckelord

Adult

Aged

Aged

80 and over

Anticholesteremic Agents

administration & dosage

adverse effects

Cholesterol

HDL

blood

Cholesterol

LDL

blood

Double-Blind Method

Female

Humans

Hypercholesterolemia

complications

drug therapy

Male

Middle Aged

Myocardial Infarction

blood

complications

Simvastatin

administration & dosage

Triglycerides

blood

Young Adult

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)