Tyck till om SwePub Sök
här!
Sökning: id:"swepub:oai:lup.lub.lu.se:1c6f2f18-3386-4cab-840e-69bfdf1e2c51" >
Depressive Symptoms...
-
Pyykkonen, Antti-Jussi
(författare)
Depressive Symptoms, Antidepressant Medication Use, and Insulin Resistance The PPP-Botnia Study
- Artikel/kapitelEngelska2011
Förlag, utgivningsår, omfång ...
-
2011-11-14
-
American Diabetes Association,2011
Nummerbeteckningar
-
LIBRIS-ID:oai:lup.lub.lu.se:1c6f2f18-3386-4cab-840e-69bfdf1e2c51
-
https://lup.lub.lu.se/record/2279318URI
-
https://doi.org/10.2337/dc11-0107DOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:art swepub-publicationtype
-
Ämneskategori:ref swepub-contenttype
Anmärkningar
-
OBJECTIVE-Although insulin resistance (IR) may underlie associations between depressive symptoms and diabetes, previous findings have been contradictory. We examined whether depressive symptoms associate with IR and insulin secretion, and, additionally, whether antidepressant medication use may modulate such associations. RESEARCH DESIGN AND METHODS-A total of 4,419 individuals underwent an oral glucose tolerance test (OGTT). Participants with previously or newly diagnosed diabetes are excluded from this sample. The homeostasis model assessment of IR (HOMA-IR) and corrected insulin response (CIR) were calculated. Depressive symptoms and antidepressant medication use were self-reported. RESULTS-After controlling for confounding factors, depressive symptoms were associated with higher fasting and 30-mM insulin during the OGTT and higher HOMA-IR but not CIR. Antidepressant medication use failed to modify these associations. CONCLUSIONS-Depressive symptoms are associated with IR but not with changes in insulin response when corrected for IR in individuals without previously or newly diagnosed diabetes.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Raikkonen, Katri
(författare)
-
Tuomi, Tiinamaija
(författare)
-
Eriksson, Johan G.
(författare)
-
Groop, LeifLund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups(Swepub:lu)endo-lgr
(författare)
-
Isomaa, Bo
(författare)
-
Genomik, diabetes och endokrinologiForskargrupper vid Lunds universitet
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Diabetes Care: American Diabetes Association34:12, s. 2545-25471935-55480149-5992
Internetlänk
Hitta via bibliotek
Till lärosätets databas